269 related articles for article (PubMed ID: 11001949)
1. Disruption of the sterol 27-hydroxylase gene in mice results in hepatomegaly and hypertriglyceridemia. Reversal by cholic acid feeding.
Repa JJ; Lund EG; Horton JD; Leitersdorf E; Russell DW; Dietschy JM; Turley SD
J Biol Chem; 2000 Dec; 275(50):39685-92. PubMed ID: 11001949
[TBL] [Abstract][Full Text] [Related]
2. Alternate pathways of bile acid synthesis in the cholesterol 7alpha-hydroxylase knockout mouse are not upregulated by either cholesterol or cholestyramine feeding.
Schwarz M; Russell DW; Dietschy JM; Turley SD
J Lipid Res; 2001 Oct; 42(10):1594-603. PubMed ID: 11590215
[TBL] [Abstract][Full Text] [Related]
3. Differential effects of sterol regulatory binding proteins 1 and 2 on sterol 12 alpha-hydroxylase. SREBP-2 suppresses the sterol 12 alpha-hydroxylase promoter.
del Castillo-Olivares A; Gil G
J Biol Chem; 2002 Feb; 277(8):6750-7. PubMed ID: 11741989
[TBL] [Abstract][Full Text] [Related]
4. Down-regulation of the rat hepatic sterol 27-hydroxylase gene by bile acids in transfected primary hepatocytes: possible role of hepatic nuclear factor 1alpha.
Rao YP; Vlahcevic ZR; Stravitz RT; Mallonee DH; Mullick J; Avadhani NG; Hylemon PB
J Steroid Biochem Mol Biol; 1999; 70(1-3):1-14. PubMed ID: 10528998
[TBL] [Abstract][Full Text] [Related]
5. Indinavir alters sterol and fatty acid homeostatic mechanisms in primary rat hepatocytes by increasing levels of activated sterol regulatory element-binding proteins and decreasing cholesterol 7alpha-hydroxylase mRNA levels.
Williams K; Rao YP; Natarajan R; Pandak WM; Hylemon PB
Biochem Pharmacol; 2004 Jan; 67(2):255-67. PubMed ID: 14698038
[TBL] [Abstract][Full Text] [Related]
6. Markedly reduced bile acid synthesis but maintained levels of cholesterol and vitamin D metabolites in mice with disrupted sterol 27-hydroxylase gene.
Rosen H; Reshef A; Maeda N; Lippoldt A; Shpizen S; Triger L; Eggertsen G; Björkhem I; Leitersdorf E
J Biol Chem; 1998 Jun; 273(24):14805-12. PubMed ID: 9614081
[TBL] [Abstract][Full Text] [Related]
7. Increased production of apolipoprotein B-containing lipoproteins in the absence of hyperlipidemia in transgenic mice expressing cholesterol 7alpha-hydroxylase.
Miyake JH; Doung XD; Strauss W; Moore GL; Castellani LW; Curtiss LK; Taylor JM; Davis RA
J Biol Chem; 2001 Jun; 276(26):23304-11. PubMed ID: 11323427
[TBL] [Abstract][Full Text] [Related]
8. Fibrates suppress bile acid synthesis via peroxisome proliferator-activated receptor-alpha-mediated downregulation of cholesterol 7alpha-hydroxylase and sterol 27-hydroxylase expression.
Post SM; Duez H; Gervois PP; Staels B; Kuipers F; Princen HM
Arterioscler Thromb Vasc Biol; 2001 Nov; 21(11):1840-5. PubMed ID: 11701475
[TBL] [Abstract][Full Text] [Related]
9. Hepatic Akt activation induces marked hypoglycemia, hepatomegaly, and hypertriglyceridemia with sterol regulatory element binding protein involvement.
Ono H; Shimano H; Katagiri H; Yahagi N; Sakoda H; Onishi Y; Anai M; Ogihara T; Fujishiro M; Viana AY; Fukushima Y; Abe M; Shojima N; Kikuchi M; Yamada N; Oka Y; Asano T
Diabetes; 2003 Dec; 52(12):2905-13. PubMed ID: 14633850
[TBL] [Abstract][Full Text] [Related]
10. Differences in hepatic levels of intermediates in bile acid biosynthesis between Cyp27(-/-) mice and CTX.
Honda A; Salen G; Matsuzaki Y; Batta AK; Xu G; Leitersdorf E; Tint GS; Erickson SK; Tanaka N; Shefer S
J Lipid Res; 2001 Feb; 42(2):291-300. PubMed ID: 11181760
[TBL] [Abstract][Full Text] [Related]
11. Altered lipid metabolism in apolipoprotein E-deficient mice does not affect cholesterol balance across the liver.
Kuipers F; van Ree JM; Hofker MH; Wolters H; In't Veld G; Havinga R; Vonk RJ; Princen HM; Havekes LM
Hepatology; 1996 Jul; 24(1):241-7. PubMed ID: 8707269
[TBL] [Abstract][Full Text] [Related]
12. Transcriptional regulation of the human sterol 27-hydroxylase gene (CYP27) and promoter mapping.
Segev H; Honigman A; Rosen H; Leitersdorf E
Atherosclerosis; 2001 Jun; 156(2):339-47. PubMed ID: 11395030
[TBL] [Abstract][Full Text] [Related]
13. Side chain hydroxylations in bile acid biosynthesis catalyzed by CYP3A are markedly up-regulated in Cyp27-/- mice but not in cerebrotendinous xanthomatosis.
Honda A; Salen G; Matsuzaki Y; Batta AK; Xu G; Leitersdorf E; Tint GS; Erickson SK; Tanaka N; Shefer S
J Biol Chem; 2001 Sep; 276(37):34579-85. PubMed ID: 11454857
[TBL] [Abstract][Full Text] [Related]
14. Different effects on the expression of CYP7 and CYP27 in rabbit liver by cholic acid and cholestyramine.
Araya Z; Sjöberg H; Wikvall K
Biochem Biophys Res Commun; 1995 Nov; 216(3):868-73. PubMed ID: 7488206
[TBL] [Abstract][Full Text] [Related]
15. Regulation of bile acid synthesis.
Chiang JY
Front Biosci; 1998 Feb; 3():d176-93. PubMed ID: 9450986
[TBL] [Abstract][Full Text] [Related]
16. Overexpression of CYP27 in hepatic and extrahepatic cells: role in the regulation of cholesterol homeostasis.
Hall E; Hylemon P; Vlahcevic Z; Mallonee D; Valerie K; Avadhani N; Pandak W
Am J Physiol Gastrointest Liver Physiol; 2001 Jul; 281(1):G293-301. PubMed ID: 11408283
[TBL] [Abstract][Full Text] [Related]
17. Elevated levels of SREBP-2 and cholesterol synthesis in livers of mice homozygous for a targeted disruption of the SREBP-1 gene.
Shimano H; Shimomura I; Hammer RE; Herz J; Goldstein JL; Brown MS; Horton JD
J Clin Invest; 1997 Oct; 100(8):2115-24. PubMed ID: 9329978
[TBL] [Abstract][Full Text] [Related]
18. Studies on the cholesterol-free mouse: strong activation of LXR-regulated hepatic genes when replacing cholesterol with desmosterol.
Heverin M; Meaney S; Brafman A; Shafir M; Olin M; Shafaati M; von Bahr S; Larsson L; Lövgren-Sandblom A; Diczfalusy U; Parini P; Feinstein E; Björkhem I
Arterioscler Thromb Vasc Biol; 2007 Oct; 27(10):2191-7. PubMed ID: 17761942
[TBL] [Abstract][Full Text] [Related]
19. Lipoprotein cholesterol uptake mediates up-regulation of bile-acid synthesis by increasing cholesterol 7alpha-hydroxylase but not sterol 27-hydroxylase gene expression in cultured rat hepatocytes.
Post SM; Twisk J; van der Fits L; de Wit EC; Hoekman MF; Mager WH; Princen HM
Biochem J; 1999 Jul; 341 ( Pt 2)(Pt 2):339-46. PubMed ID: 10393091
[TBL] [Abstract][Full Text] [Related]
20. Mechanisms of cholesterol and sterol regulatory element binding protein regulation of the sterol 12alpha-hydroxylase gene (CYP8B1).
Yang Y; Eggertsen G; Gåfvels M; Andersson U; Einarsson C; Björkhem I; Chiang JY
Biochem Biophys Res Commun; 2004 Aug; 320(4):1204-10. PubMed ID: 15249218
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
