BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

143 related articles for article (PubMed ID: 11004663)

  • 1. Tumor-derived p53 mutant C174Y is a gain-of-function mutant which activates the fos promoter and enhances colony formation.
    Preuss U; Kreutzfeld R; Scheidtmann KH
    Int J Cancer; 2000 Oct; 88(2):162-71. PubMed ID: 11004663
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Differential effects of phosphorylation of rat p53 on transactivation of promoters derived from different p53 responsive genes.
    Lohrum M; Scheidtmann KH
    Oncogene; 1996 Dec; 13(12):2527-39. PubMed ID: 9000127
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Novel human p53 mutations that are toxic to yeast can enhance transactivation of specific promoters and reactivate tumor p53 mutants.
    Inga A; Resnick MA
    Oncogene; 2001 Jun; 20(26):3409-19. PubMed ID: 11423991
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Hetero-oligomerization does not compromise 'gain of function' of tumor-derived p53 mutants.
    Deb D; Scian M; Roth KE; Li W; Keiger J; Chakraborti AS; Deb SP; Deb S
    Oncogene; 2002 Jan; 21(2):176-89. PubMed ID: 11803461
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Modulation of cellular and viral promoters by mutant human p53 proteins found in tumor cells.
    Deb S; Jackson CT; Subler MA; Martin DW
    J Virol; 1992 Oct; 66(10):6164-70. PubMed ID: 1356162
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Increased oncogenicity of subclones of SV40 large T-induced neuroectodermal tumor cell lines after loss of large T expression and concomitant mutation in p53.
    Salewski H; Bayer TA; Eidhoff U; Preuss U; Weggen S; Scheidtmann KH
    Cancer Res; 1999 Apr; 59(8):1980-6. PubMed ID: 10213510
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Dominance of wild-type p53-mediated transcriptional activation in breast epithelial cells.
    Davis P; Bazar K; Huper G; Lozano G; Marks J; Iglehart JD
    Oncogene; 1996 Sep; 13(6):1315-22. PubMed ID: 8808706
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A significant decrease of the transcriptional activity of p53 mutants deriving from human functional adrenal tumors.
    Lin SR; Yang YC; Jung JH; Tsai JH
    DNA Cell Biol; 1996 Oct; 15(10):793-803. PubMed ID: 8892752
    [TBL] [Abstract][Full Text] [Related]  

  • 9. p53 mutants can often transactivate promoters containing a p21 but not Bax or PIG3 responsive elements.
    Campomenosi P; Monti P; Aprile A; Abbondandolo A; Frebourg T; Gold B; Crook T; Inga A; Resnick MA; Iggo R; Fronza G
    Oncogene; 2001 Jun; 20(27):3573-9. PubMed ID: 11429705
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Modulation of wild-type p53 activity by mutant p53 R273H depends on the p53 responsive element (p53RE). A comparative study between the p53REs of the MDM2, WAFI/Cip1 and Bax genes in the lung cancer environment. WAFI/Cip1 = WAF1/Cip1.
    Zacharatos PV; Gorgoulis VG; Kotsinas A; Manolis EN; Liloglou T; Rassidakis AN; Kanavaros P; Field JD; Halazonetis T; Kittas C
    Anticancer Res; 1999; 19(1A):579-87. PubMed ID: 10226602
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Differential activation of target cellular promoters by p53 mutants with impaired apoptotic function.
    Ludwig RL; Bates S; Vousden KH
    Mol Cell Biol; 1996 Sep; 16(9):4952-60. PubMed ID: 8756654
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The core promoter region of the P-glycoprotein gene is sufficient to confer differential responsiveness to wild-type and mutant p53.
    Zastawny RL; Salvino R; Chen J; Benchimol S; Ling V
    Oncogene; 1993 Jun; 8(6):1529-35. PubMed ID: 8502478
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Phosphorylation of p53 at the casein kinase II site selectively regulates p53-dependent transcriptional repression but not transactivation.
    Hall SR; Campbell LE; Meek DW
    Nucleic Acids Res; 1996 Mar; 24(6):1119-26. PubMed ID: 8604347
    [TBL] [Abstract][Full Text] [Related]  

  • 14. WT1-p53 interactions in insulin-like growth factor-I receptor gene regulation.
    Idelman G; Glaser T; Roberts CT; Werner H
    J Biol Chem; 2003 Jan; 278(5):3474-82. PubMed ID: 12444079
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Inhibition of HIF-1- and wild-type p53-stimulated transcription by codon Arg175 p53 mutants with selective loss of functions.
    Blagosklonny MV; Giannakakou P; Romanova LY; Ryan KM; Vousden KH; Fojo T
    Carcinogenesis; 2001 Jun; 22(6):861-7. PubMed ID: 11375890
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Evaluation of the chemosensitivity of head and neck cancer cells based on the diverse function of mutated-p53.
    Shinagawa Y; Kawamata H; Omotehara F; Nakashiro K; Hoque MO; Furihata T; Horiuchi H; Imai Y; Fujimori T; Fujibayashi T
    Int J Oncol; 2003 Feb; 22(2):383-9. PubMed ID: 12527938
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A point mutation of human p53, which was not detected as a mutation by a yeast functional assay, led to apoptosis but not p21Waf1/Cip1/Sdi1 expression in response to ionizing radiation in a human osteosarcoma cell line, Saos-2.
    Okaichi K; Wang LH; Sasaki J; Saya H; Tada M; Okumura Y
    Int J Radiat Oncol Biol Phys; 1999 Nov; 45(4):975-80. PubMed ID: 10571205
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Investigations on a clinically and functionally unusual and novel germline p53 mutation.
    Rutherford J; Chu CE; Duddy PM; Charlton RS; Chumas P; Taylor GR; Lu X; Barnes DM; Camplejohn RS
    Br J Cancer; 2002 May; 86(10):1592-6. PubMed ID: 12085209
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Tumour associated mutants of p53 can inhibit transcriptional activity of p53 without heterooligomerization.
    Jõers A; Kristjuhan A; Kadaja L; Maimets T
    Oncogene; 1998 Nov; 17(18):2351-8. PubMed ID: 9811466
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Regulation of transcription functions of the p53 tumor suppressor by the mdm-2 oncogene.
    Chen J; Lin J; Levine AJ
    Mol Med; 1995 Jan; 1(2):142-52. PubMed ID: 8529093
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.