365 related articles for article (PubMed ID: 11006271)
21. The PI3K-PDK1 connection: more than just a road to PKB.
Vanhaesebroeck B; Alessi DR
Biochem J; 2000 Mar; 346 Pt 3(Pt 3):561-76. PubMed ID: 10698680
[TBL] [Abstract][Full Text] [Related]
22. The role of 3-phosphoinositide-dependent protein kinase 1 in activating AGC kinases defined in embryonic stem cells.
Williams MR; Arthur JS; Balendran A; van der Kaay J; Poli V; Cohen P; Alessi DR
Curr Biol; 2000 Apr; 10(8):439-48. PubMed ID: 10801415
[TBL] [Abstract][Full Text] [Related]
23. Threonine phosphorylation of the beta 3 integrin cytoplasmic tail, at a site recognized by PDK1 and Akt/PKB in vitro, regulates Shc binding.
Kirk RI; Sanderson MR; Lerea KM
J Biol Chem; 2000 Oct; 275(40):30901-6. PubMed ID: 10896934
[TBL] [Abstract][Full Text] [Related]
24. A 3-phosphoinositide-dependent protein kinase-1 (PDK1) docking site is required for the phosphorylation of protein kinase Czeta (PKCzeta ) and PKC-related kinase 2 by PDK1.
Balendran A; Biondi RM; Cheung PC; Casamayor A; Deak M; Alessi DR
J Biol Chem; 2000 Jul; 275(27):20806-13. PubMed ID: 10764742
[TBL] [Abstract][Full Text] [Related]
25. Identification of a PKB/Akt hydrophobic motif Ser-473 kinase as DNA-dependent protein kinase.
Feng J; Park J; Cron P; Hess D; Hemmings BA
J Biol Chem; 2004 Sep; 279(39):41189-96. PubMed ID: 15262962
[TBL] [Abstract][Full Text] [Related]
26. Substitution of the autophosphorylation site Thr516 with a negatively charged residue confers constitutive activity to mouse 3-phosphoinositide-dependent protein kinase-1 in cells.
Wick MJ; Wick KR; Chen H; He H; Dong LQ; Quon MJ; Liu F
J Biol Chem; 2002 May; 277(19):16632-8. PubMed ID: 11877406
[TBL] [Abstract][Full Text] [Related]
27. Role of phosphatidylinositol 3,4,5-trisphosphate in regulating the activity and localization of 3-phosphoinositide-dependent protein kinase-1.
Currie RA; Walker KS; Gray A; Deak M; Casamayor A; Downes CP; Cohen P; Alessi DR; Lucocq J
Biochem J; 1999 Feb; 337 ( Pt 3)(Pt 3):575-83. PubMed ID: 9895304
[TBL] [Abstract][Full Text] [Related]
28. Phosphorylation of the transcription factor forkhead family member FKHR by protein kinase B.
Rena G; Guo S; Cichy SC; Unterman TG; Cohen P
J Biol Chem; 1999 Jun; 274(24):17179-83. PubMed ID: 10358075
[TBL] [Abstract][Full Text] [Related]
29. Protein kinase B is regulated in platelets by the collagen receptor glycoprotein VI.
Barry FA; Gibbins JM
J Biol Chem; 2002 Apr; 277(15):12874-8. PubMed ID: 11825911
[TBL] [Abstract][Full Text] [Related]
30. Regulation of protein kinase B/Akt-serine 473 phosphorylation by integrin-linked kinase: critical roles for kinase activity and amino acids arginine 211 and serine 343.
Persad S; Attwell S; Gray V; Mawji N; Deng JT; Leung D; Yan J; Sanghera J; Walsh MP; Dedhar S
J Biol Chem; 2001 Jul; 276(29):27462-9. PubMed ID: 11313365
[TBL] [Abstract][Full Text] [Related]
31. Serine 396 of PDK1 is required for maximal PKB activation.
Moon Z; Wang Y; Aryan N; Mousseau DD; Scheid MP
Cell Signal; 2008 Nov; 20(11):2038-49. PubMed ID: 18718528
[TBL] [Abstract][Full Text] [Related]
32. Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex.
Sarbassov DD; Guertin DA; Ali SM; Sabatini DM
Science; 2005 Feb; 307(5712):1098-101. PubMed ID: 15718470
[TBL] [Abstract][Full Text] [Related]
33. Conditional knock-out of integrin-linked kinase demonstrates an essential role in protein kinase B/Akt activation.
Troussard AA; Mawji NM; Ong C; Mui A; St -Arnaud R; Dedhar S
J Biol Chem; 2003 Jun; 278(25):22374-8. PubMed ID: 12686550
[TBL] [Abstract][Full Text] [Related]
34. Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Balpha.
Alessi DR; James SR; Downes CP; Holmes AB; Gaffney PR; Reese CB; Cohen P
Curr Biol; 1997 Apr; 7(4):261-9. PubMed ID: 9094314
[TBL] [Abstract][Full Text] [Related]
35. Distinct activation mechanisms of protein kinase B by growth-factor stimulation and heat-shock treatment.
Matsuzaki H; Yamamoto T; Kikkawa U
Biochemistry; 2004 Apr; 43(14):4284-93. PubMed ID: 15065872
[TBL] [Abstract][Full Text] [Related]
36. Phosphorylation of insulin receptor substrate-1 (IRS-1) by protein kinase B positively regulates IRS-1 function.
Paz K; Liu YF; Shorer H; Hemi R; LeRoith D; Quan M; Kanety H; Seger R; Zick Y
J Biol Chem; 1999 Oct; 274(40):28816-22. PubMed ID: 10497255
[TBL] [Abstract][Full Text] [Related]
37. RET/PTC (rearranged in transformation/papillary thyroid carcinomas) tyrosine kinase phosphorylates and activates phosphoinositide-dependent kinase 1 (PDK1): an alternative phosphatidylinositol 3-kinase-independent pathway to activate PDK1.
Kim DW; Hwang JH; Suh JM; Kim H; Song JH; Hwang ES; Hwang IY; Park KC; Chung HK; Kim JM; Park J; Hemmings BA; Shong M
Mol Endocrinol; 2003 Jul; 17(7):1382-94. PubMed ID: 12738763
[TBL] [Abstract][Full Text] [Related]
38. WNK1, the kinase mutated in an inherited high-blood-pressure syndrome, is a novel PKB (protein kinase B)/Akt substrate.
Vitari AC; Deak M; Collins BJ; Morrice N; Prescott AR; Phelan A; Humphreys S; Alessi DR
Biochem J; 2004 Feb; 378(Pt 1):257-68. PubMed ID: 14611643
[TBL] [Abstract][Full Text] [Related]
39. Role of the Phox homology domain and phosphorylation in activation of serum and glucocorticoid-regulated kinase-3.
Tessier M; Woodgett JR
J Biol Chem; 2006 Aug; 281(33):23978-89. PubMed ID: 16790420
[TBL] [Abstract][Full Text] [Related]
40. Intramolecular and intermolecular interactions of protein kinase B define its activation in vivo.
Calleja V; Alcor D; Laguerre M; Park J; Vojnovic B; Hemmings BA; Downward J; Parker PJ; Larijani B
PLoS Biol; 2007 Apr; 5(4):e95. PubMed ID: 17407381
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
