BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

477 related articles for article (PubMed ID: 11007651)

  • 21. X-ray structure of TMP kinase from Mycobacterium tuberculosis complexed with TMP at 1.95 A resolution.
    Li de la Sierra I; Munier-Lehmann H; Gilles AM; Bârzu O; Delarue M
    J Mol Biol; 2001 Aug; 311(1):87-100. PubMed ID: 11469859
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Catalysis and sulfa drug resistance in dihydropteroate synthase.
    Yun MK; Wu Y; Li Z; Zhao Y; Waddell MB; Ferreira AM; Lee RE; Bashford D; White SW
    Science; 2012 Mar; 335(6072):1110-4. PubMed ID: 22383850
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Large scale molecular dynamics simulation of native and mutant dihydropteroate synthase-sulphanilamide complexes suggests the molecular basis for dihydropteroate synthase drug resistance.
    Giordanetto F; Fowler PW; Saqi M; Coveney PV
    Philos Trans A Math Phys Eng Sci; 2005 Aug; 363(1833):2055-73. PubMed ID: 16099766
    [TBL] [Abstract][Full Text] [Related]  

  • 24. The 1.9 A crystal structure of alanine racemase from Mycobacterium tuberculosis contains a conserved entryway into the active site.
    LeMagueres P; Im H; Ebalunode J; Strych U; Benedik MJ; Briggs JM; Kohn H; Krause KL
    Biochemistry; 2005 Feb; 44(5):1471-81. PubMed ID: 15683232
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Comparative protein modeling of methionine S-adenosyltransferase (MAT) enzyme from Mycobacterium tuberculosis: a potential target for antituberculosis drug discovery.
    Khedkar SA; Malde AK; Coutinho EC
    J Mol Graph Model; 2005 Jan; 23(4):355-66. PubMed ID: 15670956
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Three-dimensional structure of M. tuberculosis dihydrofolate reductase reveals opportunities for the design of novel tuberculosis drugs.
    Li R; Sirawaraporn R; Chitnumsub P; Sirawaraporn W; Wooden J; Athappilly F; Turley S; Hol WG
    J Mol Biol; 2000 Jan; 295(2):307-23. PubMed ID: 10623528
    [TBL] [Abstract][Full Text] [Related]  

  • 27. The molecular structure of ornithine acetyltransferase from Mycobacterium tuberculosis bound to ornithine, a competitive inhibitor.
    Sankaranarayanan R; Cherney MM; Garen C; Garen G; Niu C; Yuan M; James MN
    J Mol Biol; 2010 Apr; 397(4):979-90. PubMed ID: 20184895
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Crystal structure of lumazine synthase from Mycobacterium tuberculosis as a target for rational drug design: binding mode of a new class of purinetrione inhibitors.
    Morgunova E; Meining W; Illarionov B; Haase I; Jin G; Bacher A; Cushman M; Fischer M; Ladenstein R
    Biochemistry; 2005 Mar; 44(8):2746-58. PubMed ID: 15723519
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Structure-based design and development of functionalized Mercaptoguanine derivatives as inhibitors of the folate biosynthesis pathway enzyme 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase from Staphylococcus aureus.
    Dennis ML; Chhabra S; Wang ZC; Debono A; Dolezal O; Newman J; Pitcher NP; Rahmani R; Cleary B; Barlow N; Hattarki M; Graham B; Peat TS; Baell JB; Swarbrick JD
    J Med Chem; 2014 Nov; 57(22):9612-26. PubMed ID: 25357262
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Structure of the Mycobacterium tuberculosis flavin dependent thymidylate synthase (MtbThyX) at 2.0A resolution.
    Sampathkumar P; Turley S; Ulmer JE; Rhie HG; Sibley CH; Hol WG
    J Mol Biol; 2005 Oct; 352(5):1091-104. PubMed ID: 16139296
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Probing the roles of non-homologous insertions in the N-terminal domain of Plasmodium falciparum hydroxymethylpterin pyrophosphokinase-dihydropteroate synthase.
    Rattanachuen W; Jönsson M; Swedberg G; Sirawaraporn W
    Mol Biochem Parasitol; 2009 Dec; 168(2):135-42. PubMed ID: 19631695
    [TBL] [Abstract][Full Text] [Related]  

  • 32. The 1.9 A resolution structure of Mycobacterium tuberculosis 1-deoxy-D-xylulose 5-phosphate reductoisomerase, a potential drug target.
    Henriksson LM; Björkelid C; Mowbray SL; Unge T
    Acta Crystallogr D Biol Crystallogr; 2006 Jul; 62(Pt 7):807-13. PubMed ID: 16790937
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Folate synthesis in higher-plant mitochondria: coupling between the dihydropterin pyrophosphokinase and the dihydropteroate synthase activities.
    Mouillon JM; Ravanel S; Douce R; Rébeillé F
    Biochem J; 2002 Apr; 363(Pt 2):313-9. PubMed ID: 11931659
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Crystal structure of MabA from Mycobacterium tuberculosis, a reductase involved in long-chain fatty acid biosynthesis.
    Cohen-Gonsaud M; Ducasse S; Hoh F; Zerbib D; Labesse G; Quemard A
    J Mol Biol; 2002 Jul; 320(2):249-61. PubMed ID: 12079383
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Crystal structure of the Mycobacterium tuberculosis dUTPase: insights into the catalytic mechanism.
    Chan S; Segelke B; Lekin T; Krupka H; Cho US; Kim MY; So M; Kim CY; Naranjo CM; Rogers YC; Park MS; Waldo GS; Pashkov I; Cascio D; Perry JL; Sawaya MR
    J Mol Biol; 2004 Aug; 341(2):503-17. PubMed ID: 15276840
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Crystal structures of Helicobacter pylori type II dehydroquinase inhibitor complexes: new directions for inhibitor design.
    Robinson DA; Stewart KA; Price NC; Chalk PA; Coggins JR; Lapthorn AJ
    J Med Chem; 2006 Feb; 49(4):1282-90. PubMed ID: 16480265
    [TBL] [Abstract][Full Text] [Related]  

  • 37. A flexible loop at the dimer interface is a part of the active site of the adjacent monomer of Escherichia coli orotate phosphoribosyltransferase.
    Henriksen A; Aghajari N; Jensen KF; Gajhede M
    Biochemistry; 1996 Mar; 35(12):3803-9. PubMed ID: 8620002
    [TBL] [Abstract][Full Text] [Related]  

  • 38. The crystal structure of beta-ketoacyl-acyl carrier protein synthase II from Synechocystis sp. at 1.54 A resolution and its relationship to other condensing enzymes.
    Moche M; Dehesh K; Edwards P; Lindqvist Y
    J Mol Biol; 2001 Jan; 305(3):491-503. PubMed ID: 11152607
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Class-Specific Monoclonal Antibodies and Dihydropteroate Synthase in Bioassays Used for the Detection of Sulfonamides: Structural Insights into Recognition Diversity.
    Li C; Liang X; Wen K; Li Y; Zhang X; Ma M; Yu X; Yu W; Shen J; Wang Z
    Anal Chem; 2019 Feb; 91(3):2392-2400. PubMed ID: 30580515
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Mutations in the Pneumocystis jirovecii DHPS gene confer cross-resistance to sulfa drugs.
    Iliades P; Meshnick SR; Macreadie IG
    Antimicrob Agents Chemother; 2005 Feb; 49(2):741-8. PubMed ID: 15673759
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 24.