112 related articles for article (PubMed ID: 11012685)
1. Microheterogeneity of recombinant human phenylalanine hydroxylase as a result of nonenzymatic deamidations of labile amide containing amino acids. Effects on catalytic and stability properties.
Solstad T; Flatmark T
Eur J Biochem; 2000 Oct; 267(20):6302-10. PubMed ID: 11012685
[TBL] [Abstract][Full Text] [Related]
2. Deamidations in recombinant human phenylalanine hydroxylase. Identification of labile asparagine residues and functional characterization of Asn --> Asp mutant forms.
Carvalho RN; Solstad T; Bjørgo E; Barroso JF; Flatmark T
J Biol Chem; 2003 Apr; 278(17):15142-52. PubMed ID: 12554741
[TBL] [Abstract][Full Text] [Related]
3. Deamidation of labile asparagine residues in the autoregulatory sequence of human phenylalanine hydroxylase.
Solstad T; Carvalho RN; Andersen OA; Waidelich D; Flatmark T
Eur J Biochem; 2003 Mar; 270(5):929-38. PubMed ID: 12603326
[TBL] [Abstract][Full Text] [Related]
4. A comparison of kinetic and regulatory properties of the tetrameric and dimeric forms of wild-type and Thr427-->Pro mutant human phenylalanine hydroxylase: contribution of the flexible hinge region Asp425-Gln429 to the tetramerization and cooperative substrate binding.
Bjørgo E; de Carvalho RM; Flatmark T
Eur J Biochem; 2001 Feb; 268(4):997-1005. PubMed ID: 11179966
[TBL] [Abstract][Full Text] [Related]
5. Expression of recombinant human phenylalanine hydroxylase as fusion protein in Escherichia coli circumvents proteolytic degradation by host cell proteases. Isolation and characterization of the wild-type enzyme.
Martinez A; Knappskog PM; Olafsdottir S; Døskeland AP; Eiken HG; Svebak RM; Bozzini M; Apold J; Flatmark T
Biochem J; 1995 Mar; 306 ( Pt 2)(Pt 2):589-97. PubMed ID: 7887915
[TBL] [Abstract][Full Text] [Related]
6. Partial characterization and three-dimensional-structural localization of eight mutations in exon 7 of the human phenylalanine hydroxylase gene associated with phenylketonuria.
Bjørgo E; Knappskog PM; Martinez A; Stevens RC; Flatmark T
Eur J Biochem; 1998 Oct; 257(1):1-10. PubMed ID: 9799096
[TBL] [Abstract][Full Text] [Related]
7. Heterotetrameric forms of human phenylalanine hydroxylase: co-expression of wild-type and mutant forms in a bicistronic system.
Leandro J; Leandro P; Flatmark T
Biochim Biophys Acta; 2011 May; 1812(5):602-12. PubMed ID: 21315150
[TBL] [Abstract][Full Text] [Related]
8. Expression and characterization of the catalytic domain of human phenylalanine hydroxylase.
Daubner SC; Hillas PJ; Fitzpatrick PF
Arch Biochem Biophys; 1997 Dec; 348(2):295-302. PubMed ID: 9434741
[TBL] [Abstract][Full Text] [Related]
9. Structure/function relationships in human phenylalanine hydroxylase. Effect of terminal deletions on the oligomerization, activation and cooperativity of substrate binding to the enzyme.
Knappskog PM; Flatmark T; Aarden JM; Haavik J; Martínez A
Eur J Biochem; 1996 Dec; 242(3):813-21. PubMed ID: 9022714
[TBL] [Abstract][Full Text] [Related]
10. Deamidation of asparagine residues in a recombinant serine hydroxymethyltransferase.
di Salvo ML; Delle Fratte S; Maras B; Bossa F; Wright HT; Schirch V
Arch Biochem Biophys; 1999 Dec; 372(2):271-9. PubMed ID: 10600164
[TBL] [Abstract][Full Text] [Related]
11. L-phenylalanine binding and domain organization in human phenylalanine hydroxylase: a differential scanning calorimetry study.
Thórólfsson M; Ibarra-Molero B; Fojan P; Petersen SB; Sanchez-Ruiz JM; Martínez A
Biochemistry; 2002 Jun; 41(24):7573-85. PubMed ID: 12056888
[TBL] [Abstract][Full Text] [Related]
12. Substrate-induced conformational transition in human phenylalanine hydroxylase as studied by surface plasmon resonance analyses: the effect of terminal deletions, substrate analogues and phosphorylation.
Stokka AJ; Flatmark T
Biochem J; 2003 Feb; 369(Pt 3):509-18. PubMed ID: 12379147
[TBL] [Abstract][Full Text] [Related]
13. Phosphorylation and mutations of Ser(16) in human phenylalanine hydroxylase. Kinetic and structural effects.
Miranda FF; Teigen K; Thórólfsson M; Svebak RM; Knappskog PM; Flatmark T; Martínez A
J Biol Chem; 2002 Oct; 277(43):40937-43. PubMed ID: 12185072
[TBL] [Abstract][Full Text] [Related]
14. Domain structure and stability of human phenylalanine hydroxylase inferred from infrared spectroscopy.
Chehin R; Thorolfsson M; Knappskog PM; Martinez A; Flatmark T; Arrondo JL; Muga A
FEBS Lett; 1998 Jan; 422(2):225-30. PubMed ID: 9490012
[TBL] [Abstract][Full Text] [Related]
15. Spectroscopic and kinetic properties of unphosphorylated rat hepatic phenylalanine hydroxylase expressed in Escherichia coli. Comparison of resting and activated states.
Kappock TJ; Harkins PC; Friedenberg S; Caradonna JP
J Biol Chem; 1995 Dec; 270(51):30532-44. PubMed ID: 8530485
[TBL] [Abstract][Full Text] [Related]
16. Crystal structure and site-specific mutagenesis of pterin-bound human phenylalanine hydroxylase.
Erlandsen H; Bjørgo E; Flatmark T; Stevens RC
Biochemistry; 2000 Mar; 39(9):2208-17. PubMed ID: 10694386
[TBL] [Abstract][Full Text] [Related]
17. Recombinant human phenylalanine hydroxylase: novel regulatory and structural properties.
Kowlessur D; Citron BA; Kaufman S
Arch Biochem Biophys; 1996 Sep; 333(1):85-95. PubMed ID: 8806757
[TBL] [Abstract][Full Text] [Related]
18. Polyol additives modulate the in vitro stability and activity of recombinant human phenylalanine hydroxylase.
Nascimento C; Leandro J; Lino PR; Ramos L; Almeida AJ; de Almeida IT; Leandro P
Appl Biochem Biotechnol; 2010 Sep; 162(1):192-207. PubMed ID: 19937396
[TBL] [Abstract][Full Text] [Related]
19. The effect of substrate, dihydrobiopterin, and dopamine on the EPR spectroscopic properties and the midpoint potential of the catalytic iron in recombinant human phenylalanine hydroxylase.
Hagedoorn PL; Schmidt PP; Andersson KK; Hagen WR; Flatmark T; Martínez A
J Biol Chem; 2001 Jun; 276(25):22850-6. PubMed ID: 11301319
[TBL] [Abstract][Full Text] [Related]
20. Posttranslational hydroxylation of human phenylalanine hydroxylase is a novel example of enzyme self-repair within the second coordination sphere of catalytic iron.
Kinzie SD; Thevis M; Ngo K; Whitelegge J; Loo JA; Abu-Omar MM
J Am Chem Soc; 2003 Apr; 125(16):4710-1. PubMed ID: 12696880
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
