BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

183 related articles for article (PubMed ID: 11021818)

  • 1. Lack of phosphotyrosine phosphatase SHP-1 expression in malignant T-cell lymphoma cells results from methylation of the SHP-1 promoter.
    Zhang Q; Raghunath PN; Vonderheid E; Odum N; Wasik MA
    Am J Pathol; 2000 Oct; 157(4):1137-46. PubMed ID: 11021818
    [TBL] [Abstract][Full Text] [Related]  

  • 2. SHP-1 expression in peripheral T cells from patients with Sezary syndrome and in the T cell line HUT-78: implications in JAK3-mediated signaling.
    León F; Cespón C; Franco A; Lombardía M; Roldán E; Escribano L; Harto A; González-Porqué P; Roy G
    Leukemia; 2002 Aug; 16(8):1470-7. PubMed ID: 12145687
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Multi-gene epigenetic silencing of tumor suppressor genes in T-cell lymphoma cells; delayed expression of the p16 protein upon reversal of the silencing.
    Nagasawa T; Zhang Q; Raghunath PN; Wong HY; El-Salem M; Szallasi A; Marzec M; Gimotty P; Rook AH; Vonderheid EC; Odum N; Wasik MA
    Leuk Res; 2006 Mar; 30(3):303-12. PubMed ID: 16185764
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Differences in phosphorylation of the IL-2R associated JAK/STAT proteins between HTLV-I(+), IL-2-independent and IL-2-dependent cell lines and uncultured leukemic cells from patients with adult T-cell lymphoma/leukemia.
    Zhang Q; Lee B; Korecka M; Li G; Weyland C; Eck S; Gessain A; Arima N; Lessin SR; Shaw LM; Luger S; Kamoun M; Wasik MA
    Leuk Res; 1999 Apr; 23(4):373-84. PubMed ID: 10229324
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Interleukin-2 induces tyrosine phosphorylation of SHP-2 through IL-2 receptor beta chain.
    Adachi M; Ishino M; Torigoe T; Minami Y; Matozaki T; Miyazaki T; Taniguchi T; Hinoda Y; Imai K
    Oncogene; 1997 Apr; 14(13):1629-33. PubMed ID: 9129156
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Dominant negative variants of the SHP-2 tyrosine phosphatase inhibit prolactin activation of Jak2 (janus kinase 2) and induction of Stat5 (signal transducer and activator of transcription 5)-dependent transcription.
    Berchtold S; Volarevic S; Moriggl R; Mercep M; Groner B
    Mol Endocrinol; 1998 Apr; 12(4):556-67. PubMed ID: 9544991
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Restoration of shp1 expression by 5-AZA-2'-deoxycytidine is associated with downregulation of JAK3/STAT3 signaling in ALK-positive anaplastic large cell lymphoma.
    Han Y; Amin HM; Frantz C; Franko B; Lee J; Lin Q; Lai R
    Leukemia; 2006 Sep; 20(9):1602-9. PubMed ID: 16871283
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Abnormal splicing of SHP-1 protein tyrosine phosphatase in human T cells. Implications for lymphomagenesis.
    Ma XZ; Jin T; Sakac D; Fahim S; Zhang X; Katsman Y; Bali M; Branch DR
    Exp Hematol; 2003 Feb; 31(2):131-42. PubMed ID: 12591278
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The gene encoding hematopoietic cell phosphatase (SHP-1) is structurally and transcriptionally intact in polycythemia vera.
    Asimakopoulos FA; Hinshelwood S; Gilbert JG; Delibrias CC; Göttgens B; Fearon DT; Green AR
    Oncogene; 1997 Mar; 14(10):1215-22. PubMed ID: 9121771
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Catalytic-dependent and -independent roles of SHP-2 tyrosine phosphatase in interleukin-3 signaling.
    Yu WM; Hawley TS; Hawley RG; Qu CK
    Oncogene; 2003 Sep; 22(38):5995-6004. PubMed ID: 12955078
    [TBL] [Abstract][Full Text] [Related]  

  • 11. IL-2, but not IL-4 and other cytokines, induces phosphorylation of a 98-kDa protein associated with SHP-2, phosphatidylinositol 3'-kinase, and Grb2.
    Gadina M; Sudarshan C; O'Shea JJ
    J Immunol; 1999 Feb; 162(4):2081-6. PubMed ID: 9973481
    [TBL] [Abstract][Full Text] [Related]  

  • 12. STAT3- and DNA methyltransferase 1-mediated epigenetic silencing of SHP-1 tyrosine phosphatase tumor suppressor gene in malignant T lymphocytes.
    Zhang Q; Wang HY; Marzec M; Raghunath PN; Nagasawa T; Wasik MA
    Proc Natl Acad Sci U S A; 2005 May; 102(19):6948-53. PubMed ID: 15870198
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Mechanisms of SHP-1 P2 promoter regulation in hematopoietic cells and its silencing in HTLV-1-transformed T cells.
    Nakase K; Cheng J; Zhu Q; Marasco WA
    J Leukoc Biol; 2009 Jan; 85(1):165-74. PubMed ID: 18948549
    [TBL] [Abstract][Full Text] [Related]  

  • 14. B cell antigen receptor (BCR)-mediated formation of a SHP-2-pp120 complex and its inhibition by Fc gamma RIIB1-BCR coligation.
    Nakamura K; Cambier JC
    J Immunol; 1998 Jul; 161(2):684-91. PubMed ID: 9670943
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Regulation of interleukin-3-induced substrate phosphorylation and cell survival by SHP-2 (Src-homology protein tyrosine phosphatase 2).
    Wheadon H; Edmead C; Welham MJ
    Biochem J; 2003 Nov; 376(Pt 1):147-57. PubMed ID: 12935294
    [TBL] [Abstract][Full Text] [Related]  

  • 16. SHP-1 suppresses cancer cell growth by promoting degradation of JAK kinases.
    Wu C; Guan Q; Wang Y; Zhao ZJ; Zhou GW
    J Cell Biochem; 2003 Dec; 90(5):1026-37. PubMed ID: 14624462
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The function of the protein tyrosine phosphatase SHP-1 in cancer.
    Wu C; Sun M; Liu L; Zhou GW
    Gene; 2003 Mar; 306():1-12. PubMed ID: 12657462
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Expression of dominant-negative src-homology domain 2-containing protein tyrosine phosphatase-1 results in increased Syk tyrosine kinase activity and B cell activation.
    Dustin LB; Plas DR; Wong J; Hu YT; Soto C; Chan AC; Thomas ML
    J Immunol; 1999 Mar; 162(5):2717-24. PubMed ID: 10072516
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Interleukin 6 inhibits proliferation and, in cooperation with an epidermal growth factor receptor autocrine loop, increases migration of T47D breast cancer cells.
    Badache A; Hynes NE
    Cancer Res; 2001 Jan; 61(1):383-91. PubMed ID: 11196191
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Involvement of SHP-2 in multiple aspects of IL-2 signaling: evidence for a positive regulatory role.
    Gadina M; Stancato LM; Bacon CM; Larner AC; O'Shea JJ
    J Immunol; 1998 May; 160(10):4657-61. PubMed ID: 9590209
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.