176 related articles for article (PubMed ID: 11023527)
1. Nonsense mutations in the human beta-globin gene lead to unexpected levels of cytoplasmic mRNA accumulation.
Romão L; Inácio A; Santos S; Avila M; Faustino P; Pacheco P; Lavinha J
Blood; 2000 Oct; 96(8):2895-901. PubMed ID: 11023527
[TBL] [Abstract][Full Text] [Related]
2. Nonsense mutations in close proximity to the initiation codon fail to trigger full nonsense-mediated mRNA decay.
Inácio A; Silva AL; Pinto J; Ji X; Morgado A; Almeida F; Faustino P; Lavinha J; Liebhaber SA; Romão L
J Biol Chem; 2004 Jul; 279(31):32170-80. PubMed ID: 15161914
[TBL] [Abstract][Full Text] [Related]
3. Intron function in the nonsense-mediated decay of beta-globin mRNA: indications that pre-mRNA splicing in the nucleus can influence mRNA translation in the cytoplasm.
Zhang J; Sun X; Qian Y; Maquat LE
RNA; 1998 Jul; 4(7):801-15. PubMed ID: 9671053
[TBL] [Abstract][Full Text] [Related]
4. Nonsense codon mutations in the terminal exon of the beta-globin gene are not associated with a reduction in beta-mRNA accumulation: a mechanism for the phenotype of dominant beta-thalassemia.
Hall GW; Thein S
Blood; 1994 Apr; 83(8):2031-7. PubMed ID: 8161774
[TBL] [Abstract][Full Text] [Related]
5. Unspliced precursors of NMD-sensitive β-globin transcripts exhibit decreased steady-state levels in erythroid cells.
Morgado A; Almeida F; Teixeira A; Silva AL; Romão L
PLoS One; 2012; 7(6):e38505. PubMed ID: 22675570
[TBL] [Abstract][Full Text] [Related]
6. Nonsense codons in human beta-globin mRNA result in the production of mRNA degradation products.
Lim SK; Sigmund CD; Gross KW; Maquat LE
Mol Cell Biol; 1992 Mar; 12(3):1149-61. PubMed ID: 1545796
[TBL] [Abstract][Full Text] [Related]
7. Development of K562 cell clones expressing beta-globin mRNA carrying the beta039 thalassaemia mutation for the screening of correctors of stop-codon mutations.
Salvatori F; Cantale V; Breveglieri G; Zuccato C; Finotti A; Bianchi N; Borgatti M; Feriotto G; Destro F; Canella A; Breda L; Rivella S; Gambari R
Biotechnol Appl Biochem; 2009 Jul; 54(1):41-52. PubMed ID: 19216718
[TBL] [Abstract][Full Text] [Related]
8. Nonsense codons can reduce the abundance of nuclear mRNA without affecting the abundance of pre-mRNA or the half-life of cytoplasmic mRNA.
Cheng J; Maquat LE
Mol Cell Biol; 1993 Mar; 13(3):1892-902. PubMed ID: 8441420
[TBL] [Abstract][Full Text] [Related]
9. Nonsense mutations in the human beta-globin gene affect mRNA metabolism.
Baserga SJ; Benz EJ
Proc Natl Acad Sci U S A; 1988 Apr; 85(7):2056-60. PubMed ID: 3353367
[TBL] [Abstract][Full Text] [Related]
10. The delta-globin RNA transcript level in beta-thalassemia carriers.
Huang SZ; Zeng FY; Chen MJ; Ren ZR; Shen M; Rodgers GP; Schechter AN; Zeng YT
Acta Haematol; 1999; 102(1):1-6. PubMed ID: 10473880
[TBL] [Abstract][Full Text] [Related]
11. Nonsense but not missense mutations can decrease the abundance of nuclear mRNA for the mouse major urinary protein, while both types of mutations can facilitate exon skipping.
Belgrader P; Maquat LE
Mol Cell Biol; 1994 Sep; 14(9):6326-36. PubMed ID: 8065364
[TBL] [Abstract][Full Text] [Related]
12. A novel frameshift mutation (+G) at codons 15/16 in a beta0 thalassaemia gene results in a significant reduction of beta globin mRNA values.
Mo QH; Li XR; Li CF; He YL; Xu XM
J Clin Pathol; 2005 Sep; 58(9):923-6. PubMed ID: 16126871
[TBL] [Abstract][Full Text] [Related]
13. Human alpha2-globin nonsense-mediated mRNA decay induced by a novel alpha-thalassaemia frameshift mutation at codon 22.
Pereira FJ; do Céu Silva M; Picanço I; Seixas MT; Ferrão A; Faustino P; Romão L
Br J Haematol; 2006 Apr; 133(1):98-102. PubMed ID: 16512835
[TBL] [Abstract][Full Text] [Related]
14. Beta-globin nonsense mutation: deficient accumulation of mRNA occurs despite normal cytoplasmic stability.
Baserga SJ; Benz EJ
Proc Natl Acad Sci U S A; 1992 Apr; 89(7):2935-9. PubMed ID: 1557399
[TBL] [Abstract][Full Text] [Related]
15. At least one intron is required for the nonsense-mediated decay of triosephosphate isomerase mRNA: a possible link between nuclear splicing and cytoplasmic translation.
Zhang J; Sun X; Qian Y; LaDuca JP; Maquat LE
Mol Cell Biol; 1998 Sep; 18(9):5272-83. PubMed ID: 9710612
[TBL] [Abstract][Full Text] [Related]
16. Dominantly Inherited beta-Thalassemia.
Efremov GD
Hemoglobin; 2007; 31(2):193-207. PubMed ID: 17486503
[TBL] [Abstract][Full Text] [Related]
17. The beta-globin C-->G mutation at 6 bp 3' to the termination codon causes beta-thalassaemia by decreasing the mRNA level.
Sgourou A; Papachatzopoulou A; Psiouri L; Antoniou M; Zoumbos N; Gibbs R; Athanassiadou A
Br J Haematol; 2002 Aug; 118(2):671-6. PubMed ID: 12139763
[TBL] [Abstract][Full Text] [Related]
18. Development of viral vectors for gene therapy of beta-chain hemoglobinopathies: optimization of a gamma-globin gene expression cassette.
Li Q; Emery DW; Fernandez M; Han H; Stamatoyannopoulos G
Blood; 1999 Apr; 93(7):2208-16. PubMed ID: 10090929
[TBL] [Abstract][Full Text] [Related]
19. New amber mutation in a beta-thalassemic gene with nonmeasurable levels of mutant messenger RNA in vivo.
Atweh GF; Brickner HE; Zhu XX; Kazazian HH; Forget BG
J Clin Invest; 1988 Aug; 82(2):557-61. PubMed ID: 3403716
[TBL] [Abstract][Full Text] [Related]
20. Molecular mechanism of beta-thalassaemia caused by 22-bp duplication.
Svasti S; Boonchoy C; Vanichsetakul P; Winichagoon P; Fucharoen S
Ann Hematol; 2008 Aug; 87(8):633-7. PubMed ID: 18392622
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
