BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

87 related articles for article (PubMed ID: 11023980)

  • 1. Increased susceptibility to ischemia-induced brain damage in transgenic mice overexpressing a dominant negative form of SHP2.
    Aoki Y; Huang Z; Thomas SS; Bhide PG; Huang I; Moskowitz MA; Reeves SA
    FASEB J; 2000 Oct; 14(13):1965-73. PubMed ID: 11023980
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The protein tyrosine phosphatase, Shp2, is required for the complete activation of the RAS/MAPK pathway by brain-derived neurotrophic factor.
    Easton JB; Royer AR; Middlemas DS
    J Neurochem; 2006 May; 97(3):834-45. PubMed ID: 16573649
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The SH2 tyrosine phosphatase shp2 is required for mammalian limb development.
    Saxton TM; Ciruna BG; Holmyard D; Kulkarni S; Harpal K; Rossant J; Pawson T
    Nat Genet; 2000 Apr; 24(4):420-3. PubMed ID: 10742110
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Negative regulation of myeloid cell proliferation and function by the SH2 domain-containing tyrosine phosphatase-1.
    Dong Q; Siminovitch KA; Fialkow L; Fukushima T; Downey GP
    J Immunol; 1999 Mar; 162(6):3220-30. PubMed ID: 10092773
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A novel function for the protein tyrosine phosphatase Shp2 during lung branching morphogenesis.
    Tefft D; De Langhe SP; Del Moral PM; Sala F; Shi W; Bellusci S; Warburton D
    Dev Biol; 2005 Jun; 282(2):422-31. PubMed ID: 15950607
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Activating mutations of the noonan syndrome-associated SHP2/PTPN11 gene in human solid tumors and adult acute myelogenous leukemia.
    Bentires-Alj M; Paez JG; David FS; Keilhack H; Halmos B; Naoki K; Maris JM; Richardson A; Bardelli A; Sugarbaker DJ; Richards WG; Du J; Girard L; Minna JD; Loh ML; Fisher DE; Velculescu VE; Vogelstein B; Meyerson M; Sellers WR; Neel BG
    Cancer Res; 2004 Dec; 64(24):8816-20. PubMed ID: 15604238
    [TBL] [Abstract][Full Text] [Related]  

  • 7. SHP2 associates directly with tyrosine phosphorylated p90 (SNT) protein in FGF-stimulated cells.
    Ong SH; Lim YP; Low BC; Guy GR
    Biochem Biophys Res Commun; 1997 Sep; 238(1):261-6. PubMed ID: 9299490
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Modulation of insulin-stimulated glycogen synthesis by Src Homology Phosphatase 2.
    Ouwens DM; van der Zon GC; Maassen JA
    Mol Cell Endocrinol; 2001 Apr; 175(1-2):131-40. PubMed ID: 11325523
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The Src-homology domain 2-bearing protein tyrosine phosphatase-1 inhibits antigen receptor-induced apoptosis of activated peripheral T cells.
    Zhang J; Somani AK; Watt S; Mills GB; Siminovitch KA
    J Immunol; 1999 Jun; 162(11):6359-67. PubMed ID: 10352248
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Shp2 is dispensable in the formation and maintenance of the neuromuscular junction.
    Dong XP; Li XM; Gao TM; Zhang EE; Feng GS; Xiong WC; Mei L
    Neurosignals; 2006-2007; 15(2):53-63. PubMed ID: 16837792
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Abnormal mesoderm patterning in mouse embryos mutant for the SH2 tyrosine phosphatase Shp-2.
    Saxton TM; Henkemeyer M; Gasca S; Shen R; Rossi DJ; Shalaby F; Feng GS; Pawson T
    EMBO J; 1997 May; 16(9):2352-64. PubMed ID: 9171349
    [TBL] [Abstract][Full Text] [Related]  

  • 12. SHP-2 regulates the phosphatidylinositide 3'-kinase/Akt pathway and suppresses caspase 3-mediated apoptosis.
    Ivins Zito C; Kontaridis MI; Fornaro M; Feng GS; Bennett AM
    J Cell Physiol; 2004 May; 199(2):227-36. PubMed ID: 15040005
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Inhibition of EGFR-mediated phosphoinositide-3-OH kinase (PI3-K) signaling and glioblastoma phenotype by signal-regulatory proteins (SIRPs).
    Wu CJ; Chen Z; Ullrich A; Greene MI; O'Rourke DM
    Oncogene; 2000 Aug; 19(35):3999-4010. PubMed ID: 10962556
    [TBL] [Abstract][Full Text] [Related]  

  • 14. ROS fusion tyrosine kinase activates a SH2 domain-containing phosphatase-2/phosphatidylinositol 3-kinase/mammalian target of rapamycin signaling axis to form glioblastoma in mice.
    Charest A; Wilker EW; McLaughlin ME; Lane K; Gowda R; Coven S; McMahon K; Kovach S; Feng Y; Yaffe MB; Jacks T; Housman D
    Cancer Res; 2006 Aug; 66(15):7473-81. PubMed ID: 16885344
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The Shp-2 tyrosine phosphatase activates the Src tyrosine kinase by a non-enzymatic mechanism.
    Walter AO; Peng ZY; Cartwright CA
    Oncogene; 1999 Mar; 18(11):1911-20. PubMed ID: 10208413
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Regulation of neuregulin-mediated acetylcholine receptor synthesis by protein tyrosine phosphatase SHP2.
    Tanowitz M; Si J; Yu DH; Feng GS; Mei L
    J Neurosci; 1999 Nov; 19(21):9426-35. PubMed ID: 10531446
    [TBL] [Abstract][Full Text] [Related]  

  • 17. SH2 domain containing protein tyrosine phosphatase 2 regulates concanavalin A-dependent secretion and activation of matrix metalloproteinase 2 via the extracellular signal-regulated kinase and p38 pathways.
    Ruhul Amin AR; Oo ML; Senga T; Suzuki N; Feng GS; Hamaguchi M
    Cancer Res; 2003 Oct; 63(19):6334-9. PubMed ID: 14559821
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Shp-2 has a positive regulatory role in ES cell differentiation and proliferation.
    Qu CK; Feng GS
    Oncogene; 1998 Jul; 17(4):433-9. PubMed ID: 9696036
    [TBL] [Abstract][Full Text] [Related]  

  • 19. An Shp2/SFK/Ras/Erk signaling pathway controls trophoblast stem cell survival.
    Yang W; Klaman LD; Chen B; Araki T; Harada H; Thomas SM; George EL; Neel BG
    Dev Cell; 2006 Mar; 10(3):317-27. PubMed ID: 16516835
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The src homology 2 domain-containing tyrosine phosphatase 2 regulates primary T-dependent immune responses and Th cell differentiation.
    Salmond RJ; Huyer G; Kotsoni A; Clements L; Alexander DR
    J Immunol; 2005 Nov; 175(10):6498-508. PubMed ID: 16272304
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 5.