These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

326 related articles for article (PubMed ID: 11027274)

  • 1. Positive and negative regulation of phosphoinositide 3-kinase-dependent signaling pathways by three different gene products of the p85alpha regulatory subunit.
    Ueki K; Algenstaedt P; Mauvais-Jarvis F; Kahn CR
    Mol Cell Biol; 2000 Nov; 20(21):8035-46. PubMed ID: 11027274
    [TBL] [Abstract][Full Text] [Related]  

  • 2. p85alpha gene generates three isoforms of regulatory subunit for phosphatidylinositol 3-kinase (PI 3-Kinase), p50alpha, p55alpha, and p85alpha, with different PI 3-kinase activity elevating responses to insulin.
    Inukai K; Funaki M; Ogihara T; Katagiri H; Kanda A; Anai M; Fukushima Y; Hosaka T; Suzuki M; Shin BC; Takata K; Yazaki Y; Kikuchi M; Oka Y; Asano T
    J Biol Chem; 1997 Mar; 272(12):7873-82. PubMed ID: 9065454
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Positive and negative roles of p85 alpha and p85 beta regulatory subunits of phosphoinositide 3-kinase in insulin signaling.
    Ueki K; Fruman DA; Yballe CM; Fasshauer M; Klein J; Asano T; Cantley LC; Kahn CR
    J Biol Chem; 2003 Nov; 278(48):48453-66. PubMed ID: 14504291
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Insulin receptor substrate 1 binds two novel splice variants of the regulatory subunit of phosphatidylinositol 3-kinase in muscle and brain.
    Antonetti DA; Algenstaedt P; Kahn CR
    Mol Cell Biol; 1996 May; 16(5):2195-203. PubMed ID: 8628286
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Expression of the splice variants of the p85alpha regulatory subunit of phosphoinositide 3-kinase in muscle and adipose tissue of healthy subjects and type 2 diabetic patients.
    Lefai E; Roques M; Vega N; Laville M; Vidal H
    Biochem J; 2001 Nov; 360(Pt 1):117-26. PubMed ID: 11695998
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Overexpression of SH2-containing inositol phosphatase 2 results in negative regulation of insulin-induced metabolic actions in 3T3-L1 adipocytes via its 5'-phosphatase catalytic activity.
    Wada T; Sasaoka T; Funaki M; Hori H; Murakami S; Ishiki M; Haruta T; Asano T; Ogawa W; Ishihara H; Kobayashi M
    Mol Cell Biol; 2001 Mar; 21(5):1633-46. PubMed ID: 11238900
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Inhibition of phosphatidylinositol 3-kinase activity by adenovirus-mediated gene transfer and its effect on insulin action.
    Sharma PM; Egawa K; Huang Y; Martin JL; Huvar I; Boss GR; Olefsky JM
    J Biol Chem; 1998 Jul; 273(29):18528-37. PubMed ID: 9660823
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Membrane-targeted phosphatidylinositol 3-kinase mimics insulin actions and induces a state of cellular insulin resistance.
    Egawa K; Sharma PM; Nakashima N; Huang Y; Huver E; Boss GR; Olefsky JM
    J Biol Chem; 1999 May; 274(20):14306-14. PubMed ID: 10318852
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Specific increase in p85alpha expression in response to dexamethasone is associated with inhibition of insulin-like growth factor-I stimulated phosphatidylinositol 3-kinase activity in cultured muscle cells.
    Giorgino F; Pedrini MT; Matera L; Smith RJ
    J Biol Chem; 1997 Mar; 272(11):7455-63. PubMed ID: 9054447
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Growth factor receptor-binding protein 10 (Grb10) as a partner of phosphatidylinositol 3-kinase in metabolic insulin action.
    Deng Y; Bhattacharya S; Swamy OR; Tandon R; Wang Y; Janda R; Riedel H
    J Biol Chem; 2003 Oct; 278(41):39311-22. PubMed ID: 12783867
    [TBL] [Abstract][Full Text] [Related]  

  • 11. SH2-containing inositol phosphatase 2 negatively regulates insulin-induced glycogen synthesis in L6 myotubes.
    Sasaoka T; Hori H; Wada T; Ishiki M; Haruta T; Ishihara H; Kobayashi M
    Diabetologia; 2001 Oct; 44(10):1258-67. PubMed ID: 11692174
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The SH3 and BH domains of the p85alpha adapter subunit play a critical role in regulating class Ia phosphoinositide 3-kinase function.
    Beeton CA; Das P; Waterfield MD; Shepherd PR
    Mol Cell Biol Res Commun; 1999 May; 1(2):153-7. PubMed ID: 10356365
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Differential signaling by regulatory subunits of phosphoinositide-3-kinase influences cell survival in INS-1E insulinoma cells.
    Schrader J; Niebel P; Rossi A; Archontidou-Aprin E; Hörsch D
    Exp Clin Endocrinol Diabetes; 2015 Feb; 123(2):118-25. PubMed ID: 25393342
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Mammalian target of rapamycin pathway regulates insulin signaling via subcellular redistribution of insulin receptor substrate 1 and integrates nutritional signals and metabolic signals of insulin.
    Takano A; Usui I; Haruta T; Kawahara J; Uno T; Iwata M; Kobayashi M
    Mol Cell Biol; 2001 Aug; 21(15):5050-62. PubMed ID: 11438661
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Synergistic activation of a family of phosphoinositide 3-kinase via G-protein coupled and tyrosine kinase-related receptors.
    Katada T; Kurosu H; Okada T; Suzuki T; Tsujimoto N; Takasuga S; Kontani K; Hazeki O; Ui M
    Chem Phys Lipids; 1999 Apr; 98(1-2):79-86. PubMed ID: 10358930
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Calorie restriction increases the ratio of phosphatidylinositol 3-kinase catalytic to regulatory subunits in rat skeletal muscle.
    McCurdy CE; Davidson RT; Cartee GD
    Am J Physiol Endocrinol Metab; 2005 May; 288(5):E996-E1001. PubMed ID: 15613677
    [TBL] [Abstract][Full Text] [Related]  

  • 17. p110beta is up-regulated during differentiation of 3T3-L1 cells and contributes to the highly insulin-responsive glucose transport activity.
    Asano T; Kanda A; Katagiri H; Nawano M; Ogihara T; Inukai K; Anai M; Fukushima Y; Yazaki Y; Kikuchi M; Hooshmand-Rad R; Heldin CH; Oka Y; Funaki M
    J Biol Chem; 2000 Jun; 275(23):17671-6. PubMed ID: 10748220
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Interaction of wild type and dominant-negative p55PIK regulatory subunit of phosphatidylinositol 3-kinase with insulin-like growth factor-1 signaling proteins.
    Mothe I; Delahaye L; Filloux C; Pons S; White MF; Van Obberghen E
    Mol Endocrinol; 1997 Dec; 11(13):1911-23. PubMed ID: 9415396
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Amino acid and insulin signaling via the mTOR/p70 S6 kinase pathway. A negative feedback mechanism leading to insulin resistance in skeletal muscle cells.
    Tremblay F; Marette A
    J Biol Chem; 2001 Oct; 276(41):38052-60. PubMed ID: 11498541
    [TBL] [Abstract][Full Text] [Related]  

  • 20. p50alpha/p55alpha phosphoinositide 3-kinase knockout mice exhibit enhanced insulin sensitivity.
    Chen D; Mauvais-Jarvis F; Bluher M; Fisher SJ; Jozsi A; Goodyear LJ; Ueki K; Kahn CR
    Mol Cell Biol; 2004 Jan; 24(1):320-9. PubMed ID: 14673165
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 17.