BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

87 related articles for article (PubMed ID: 11034781)

  • 21. Kinetic deuterium isotope effects for 7-alkoxycoumarin O-dealkylation reactions catalyzed by human cytochromes P450 and in liver microsomes. Rate-limiting C-H bond breaking in cytochrome P450 1A2 substrate oxidation.
    Kim KH; Isin EM; Yun CH; Kim DH; Guengerich FP
    FEBS J; 2006 May; 273(10):2223-31. PubMed ID: 16649998
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Isochorismate pyruvate lyase: a pericyclic reaction mechanism?
    DeClue MS; Baldridge KK; Künzler DE; Kast P; Hilvert D
    J Am Chem Soc; 2005 Nov; 127(43):15002-3. PubMed ID: 16248620
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Sialic acid biosynthesis: stereochemistry and mechanism of the reaction catalyzed by the mammalian UDP-N-acetylglucosamine 2-epimerase.
    Chou WK; Hinderlich S; Reutter W; Tanner ME
    J Am Chem Soc; 2003 Mar; 125(9):2455-61. PubMed ID: 12603133
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Mycobacterium tuberculosis beta-ketoacyl-acyl carrier protein (ACP) reductase: kinetic and chemical mechanisms.
    Silva RG; de Carvalho LP; Blanchard JS; Santos DS; Basso LA
    Biochemistry; 2006 Oct; 45(43):13064-73. PubMed ID: 17059223
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Determining the transition-state structure for different SN2 reactions using experimental nucleophile carbon and secondary alpha-deuterium kinetic isotope effects and theory.
    Westaway KC; Fang YR; MacMillar S; Matsson O; Poirier RA; Islam SM
    J Phys Chem A; 2008 Oct; 112(41):10264-73. PubMed ID: 18816038
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Studies with substrate and cofactor analogues provide evidence for a radical mechanism in the chorismate synthase reaction.
    Osborne A; Thorneley RN; Abell C; Bornemann S
    J Biol Chem; 2000 Nov; 275(46):35825-30. PubMed ID: 10956653
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Novel pathways for oxygen insertion into unactivated C-H bonds by dioxiranes. Transition structures for stepwise routes via radical pairs and comparison with the concerted pathway.
    Freccero M; Gandolfi R; Sarzi-Amadè M; Rastelli A
    J Org Chem; 2003 Feb; 68(3):811-23. PubMed ID: 12558403
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Studies with flavin analogs provide evidence that a protonated reduced FMN is the substrate-induced transient intermediate in the reaction of Escherichia coli chorismate synthase.
    Macheroux P; Bornemann S; Ghisla S; Thorneley RN
    J Biol Chem; 1996 Oct; 271(42):25850-8. PubMed ID: 8824216
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Crystal structure of the reaction complex of 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase from Thermotoga maritima refines the catalytic mechanism and indicates a new mechanism of allosteric regulation.
    Shumilin IA; Bauerle R; Wu J; Woodard RW; Kretsinger RH
    J Mol Biol; 2004 Aug; 341(2):455-66. PubMed ID: 15276836
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Is the bound substrate in nitric oxide synthase protonated or neutral and what is the active oxidant that performs substrate hydroxylation?
    de Visser SP; Tan LS
    J Am Chem Soc; 2008 Oct; 130(39):12961-74. PubMed ID: 18774806
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Steady-state and laser flash photolysis study of the carbon-carbon bond fragmentation reactions of 2-arylsulfanyl alcohol radical cations.
    Baciocchi E; Giacco TD; Elisei F; Gerini MF; Lapi A; Liberali P; Uzzoli B
    J Org Chem; 2004 Nov; 69(24):8323-30. PubMed ID: 15549803
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Mechanistic analysis of the unusual redox-elimination sequence employed by Thermotoga maritima BglT: a 6-phospho-beta-glucosidase from glycoside hydrolase family 4.
    Yip VL; Withers SG
    Biochemistry; 2006 Jan; 45(2):571-80. PubMed ID: 16401086
    [TBL] [Abstract][Full Text] [Related]  

  • 33. A kinetic study of the reaction of N,N-dimethylanilines with 2,2-diphenyl-1-picrylhydrazyl radical: a concerted proton-electron transfer?
    Baciocchi E; Calcagni A; Lanzalunga O
    J Org Chem; 2008 Jun; 73(11):4110-5. PubMed ID: 18459733
    [TBL] [Abstract][Full Text] [Related]  

  • 34. The reaction of indole with the aminoacrylate intermediate of Salmonella typhimurium tryptophan synthase: observation of a primary kinetic isotope effect with 3-[(2)H]indole.
    Cash MT; Miles EW; Phillips RS
    Arch Biochem Biophys; 2004 Dec; 432(2):233-43. PubMed ID: 15542062
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Dynamics of glyphosate-induced conformational changes of Mycobacterium tuberculosis 5-enolpyruvylshikimate-3-phosphate synthase (EC 2.5.1.19) determined by hydrogen-deuterium exchange and electrospray mass spectrometry.
    Marques MR; Vaso A; Neto JR; Fossey MA; Oliveira JS; Basso LA; dos Santos DS; de Azevedo Junior WF; Palma MS
    Biochemistry; 2008 Jul; 47(28):7509-22. PubMed ID: 18558720
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Stereoselective hydrogen abstraction by galactose oxidase.
    Minasian SG; Whittaker MM; Whittaker JW
    Biochemistry; 2004 Nov; 43(43):13683-93. PubMed ID: 15504031
    [TBL] [Abstract][Full Text] [Related]  

  • 37. A proton-shuttle mechanism mediated by the porphyrin in benzene hydroxylation by cytochrome p450 enzymes.
    de Visser SP; Shaik S
    J Am Chem Soc; 2003 Jun; 125(24):7413-24. PubMed ID: 12797816
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Kinetic and chemical mechanisms of shikimate dehydrogenase from Mycobacterium tuberculosis.
    Fonseca IO; Silva RG; Fernandes CL; de Souza ON; Basso LA; Santos DS
    Arch Biochem Biophys; 2007 Jan; 457(2):123-33. PubMed ID: 17178095
    [TBL] [Abstract][Full Text] [Related]  

  • 39. 13C and 15N isotope effects for conversion of L-dihydroorotate to N-carbamyl-L-aspartate using dihydroorotase from hamster and Bacillus caldolyticus.
    Anderson MA; Cleland WW; Huang DT; Chan C; Shojaei M; Christopherson RI
    Biochemistry; 2006 Jun; 45(23):7132-9. PubMed ID: 16752903
    [TBL] [Abstract][Full Text] [Related]  

  • 40. The mechanism for isopenicillin N synthase from density-functional modeling highlights the similarities with other enzymes in the 2-His-1-carboxylate family.
    Lundberg M; Siegbahn PE; Morokuma K
    Biochemistry; 2008 Jan; 47(3):1031-42. PubMed ID: 18163649
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 5.