BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

168 related articles for article (PubMed ID: 11035034)

  • 1. Isolation of a 40-kDa Huntingtin-associated protein.
    Peters MF; Ross CA
    J Biol Chem; 2001 Feb; 276(5):3188-94. PubMed ID: 11035034
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Expansion of polyglutamine repeat in huntingtin leads to abnormal protein interactions involving calmodulin.
    Bao J; Sharp AH; Wagster MV; Becher M; Schilling G; Ross CA; Dawson VL; Dawson TM
    Proc Natl Acad Sci U S A; 1996 May; 93(10):5037-42. PubMed ID: 8643525
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Amyloid formation by mutant huntingtin: threshold, progressivity and recruitment of normal polyglutamine proteins.
    Huang CC; Faber PW; Persichetti F; Mittal V; Vonsattel JP; MacDonald ME; Gusella JF
    Somat Cell Mol Genet; 1998 Jul; 24(4):217-33. PubMed ID: 10410676
    [TBL] [Abstract][Full Text] [Related]  

  • 4. HAP40 is a conserved central regulator of Huntingtin and a potential modulator of Huntington's disease pathogenesis.
    Xu S; Li G; Ye X; Chen D; Chen Z; Xu Z; Daniele M; Tambone S; Ceccacci A; Tomei L; Ye L; Yu Y; Solbach A; Farmer SM; Stimming EF; McAllister G; Marchionini DM; Zhang S
    PLoS Genet; 2022 Jul; 18(7):e1010302. PubMed ID: 35853002
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Pathological polyQ expansion does not alter the conformation of the Huntingtin-HAP40 complex.
    Huang B; Guo Q; Niedermeier ML; Cheng J; Engler T; Maurer M; Pautsch A; Baumeister W; Stengel F; Kochanek S; Fernández-Busnadiego R
    Structure; 2021 Aug; 29(8):804-809.e5. PubMed ID: 33909994
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Truncated N-terminal fragments of huntingtin with expanded glutamine repeats form nuclear and cytoplasmic aggregates in cell culture.
    Cooper JK; Schilling G; Peters MF; Herring WJ; Sharp AH; Kaminsky Z; Masone J; Khan FA; Delanoy M; Borchelt DR; Dawson VL; Dawson TM; Ross CA
    Hum Mol Genet; 1998 May; 7(5):783-90. PubMed ID: 9536081
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Inhibition of p38 Mitogen-Activated Protein Kinase Ameliorates HAP40 Depletion-Induced Toxicity and Proteasomal Defect in Huntington's Disease Model.
    Huang ZN; Chen JM; Huang LC; Fang YH; Her LS
    Mol Neurobiol; 2021 Jun; 58(6):2704-2723. PubMed ID: 33492644
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Huntingtin-HAP40 complex is a novel Rab5 effector that regulates early endosome motility and is up-regulated in Huntington's disease.
    Pal A; Severin F; Lommer B; Shevchenko A; Zerial M
    J Cell Biol; 2006 Feb; 172(4):605-18. PubMed ID: 16476778
    [TBL] [Abstract][Full Text] [Related]  

  • 9. PACSIN 1 interacts with huntingtin and is absent from synaptic varicosities in presymptomatic Huntington's disease brains.
    Modregger J; DiProspero NA; Charles V; Tagle DA; Plomann M
    Hum Mol Genet; 2002 Oct; 11(21):2547-58. PubMed ID: 12354780
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Huntingtin and Its Partner Huntingtin-Associated Protein 40: Structural and Functional Considerations in Health and Disease.
    Seefelder M; Klein FAC; Landwehrmeyer B; Fernández-Busnadiego R; Kochanek S
    J Huntingtons Dis; 2022; 11(3):227-242. PubMed ID: 35871360
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Nucleocytoplasmic trafficking and transcription effects of huntingtin in Huntington's disease.
    Truant R; Atwal RS; Burtnik A
    Prog Neurobiol; 2007 Nov; 83(4):211-27. PubMed ID: 17240517
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Differential distribution of the normal and mutated forms of huntingtin in the human brain.
    Gourfinkel-An I; Cancel G; Trottier Y; Devys D; Tora L; Lutz Y; Imbert G; Saudou F; Stevanin G; Agid Y; Brice A; Mandel JL; Hirsch EC
    Ann Neurol; 1997 Nov; 42(5):712-9. PubMed ID: 9392570
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Expression of full-length polyglutamine-expanded Huntingtin disrupts growth factor receptor signaling in rat pheochromocytoma (PC12) cells.
    Song C; Perides G; Liu YF
    J Biol Chem; 2002 Feb; 277(8):6703-7. PubMed ID: 11733534
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Lentiviral-mediated delivery of mutant huntingtin in the striatum of rats induces a selective neuropathology modulated by polyglutamine repeat size, huntingtin expression levels, and protein length.
    de Almeida LP; Ross CA; Zala D; Aebischer P; Déglon N
    J Neurosci; 2002 May; 22(9):3473-83. PubMed ID: 11978824
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Huntingtin structure is orchestrated by HAP40 and shows a polyglutamine expansion-specific interaction with exon 1.
    Harding RJ; Deme JC; Hevler JF; Tamara S; Lemak A; Cantle JP; Szewczyk MM; Begeja N; Goss S; Zuo X; Loppnau P; Seitova A; Hutchinson A; Fan L; Truant R; Schapira M; Carroll JB; Heck AJR; Lea SM; Arrowsmith CH
    Commun Biol; 2021 Dec; 4(1):1374. PubMed ID: 34880419
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Huntingtin contains a highly conserved nuclear export signal.
    Xia J; Lee DH; Taylor J; Vandelft M; Truant R
    Hum Mol Genet; 2003 Jun; 12(12):1393-403. PubMed ID: 12783847
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The evolution of the huntingtin-associated protein 40 (HAP40) in conjunction with huntingtin.
    Seefelder M; Alva V; Huang B; Engler T; Baumeister W; Guo Q; Fernández-Busnadiego R; Lupas AN; Kochanek S
    BMC Evol Biol; 2020 Dec; 20(1):162. PubMed ID: 33297953
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Essential sequence of the N-terminal cytoplasmic localization-related domain of huntingtin and its effect on huntingtin aggregates.
    Yan Y; Peng D; Tian J; Chi J; Tan J; Yin X; Pu J; Xia K; Zhang B
    Sci China Life Sci; 2011 Apr; 54(4):342-50. PubMed ID: 21509658
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Evidence for both the nucleus and cytoplasm as subcellular sites of pathogenesis in Huntington's disease in cell culture and in transgenic mice expressing mutant huntingtin.
    Hackam AS; Hodgson JG; Singaraja R; Zhang T; Gan L; Gutekunst CA; Hersch SM; Hayden MR
    Philos Trans R Soc Lond B Biol Sci; 1999 Jun; 354(1386):1047-55. PubMed ID: 10434304
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Sensitive biochemical aggregate detection reveals aggregation onset before symptom development in cellular and murine models of Huntington's disease.
    Weiss A; Klein C; Woodman B; Sathasivam K; Bibel M; Régulier E; Bates GP; Paganetti P
    J Neurochem; 2008 Feb; 104(3):846-58. PubMed ID: 17986219
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.