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2. Catalytic properties of NAD(P)H:quinone oxidoreductase-2 (NQO2), a dihydronicotinamide riboside dependent oxidoreductase. Wu K; Knox R; Sun XZ; Joseph P; Jaiswal AK; Zhang D; Deng PS; Chen S Arch Biochem Biophys; 1997 Nov; 347(2):221-8. PubMed ID: 9367528 [TBL] [Abstract][Full Text] [Related]
3. NAD(P)H:quinone oxidoreductase 1 and nrh:quinone oxidoreductase 2 activity and expression in bladder and ovarian cancer and lower NRH:quinone oxidoreductase 2 activity associated with an NQO2 exon 3 single-nucleotide polymorphism. Jamieson D; Wilson K; Pridgeon S; Margetts JP; Edmondson RJ; Leung HY; Knox R; Boddy AV Clin Cancer Res; 2007 Mar; 13(5):1584-90. PubMed ID: 17332305 [TBL] [Abstract][Full Text] [Related]
4. Reduction and Scavenging of Chemically Reactive Drug Metabolites by NAD(P)H:Quinone Oxidoreductase 1 and NRH:Quinone Oxidoreductase 2 and Variability in Hepatic Concentrations. den Braver-Sewradj SP; den Braver MW; Toorneman RM; van Leeuwen S; Zhang Y; Dekker SJ; Vermeulen NPE; Commandeur JNM; Vos JC Chem Res Toxicol; 2018 Feb; 31(2):116-126. PubMed ID: 29281794 [TBL] [Abstract][Full Text] [Related]
5. Molecular characterization of binding of substrates and inhibitors to DT-diaphorase: combined approach involving site-directed mutagenesis, inhibitor-binding analysis, and computer modeling. Chen S; Wu K; Zhang D; Sherman M; Knox R; Yang CS Mol Pharmacol; 1999 Aug; 56(2):272-8. PubMed ID: 10419545 [TBL] [Abstract][Full Text] [Related]
6. A site-directed mutagenesis study at Lys-113 of NAD(P)H:quinone-acceptor oxidoreductase: an involvement of Lys-113 in the binding of the flavin adenine dinucleotide prosthetic group. Tedeschi G; Deng PS; Chen HH; Forrest GL; Massey V; Chen S Arch Biochem Biophys; 1995 Aug; 321(1):76-82. PubMed ID: 7639539 [TBL] [Abstract][Full Text] [Related]
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9. Evidence for NQO2-mediated reduction of the carcinogenic estrogen ortho-quinones. Gaikwad NW; Yang L; Rogan EG; Cavalieri EL Free Radic Biol Med; 2009 Jan; 46(2):253-62. PubMed ID: 18996184 [TBL] [Abstract][Full Text] [Related]
10. Thiol oxidation coupled to DT-diaphorase-catalysed reduction of diaziquone. Reductive and oxidative pathways of diaziquone semiquinone modulated by glutathione and superoxide dismutase. OrdoƱez ID; Cadenas E Biochem J; 1992 Sep; 286 ( Pt 2)(Pt 2):481-90. PubMed ID: 1530580 [TBL] [Abstract][Full Text] [Related]
11. Bioactivation of 5-(aziridin-1-yl)-2,4-dinitrobenzamide (CB 1954) by human NAD(P)H quinone oxidoreductase 2: a novel co-substrate-mediated antitumor prodrug therapy. Knox RJ; Jenkins TC; Hobbs SM; Chen S; Melton RG; Burke PJ Cancer Res; 2000 Aug; 60(15):4179-86. PubMed ID: 10945627 [TBL] [Abstract][Full Text] [Related]
12. Cancer-associated variants of human NQO1: impacts on inhibitor binding and cooperativity. Megarity CF; Timson DJ Biosci Rep; 2019 Sep; 39(9):. PubMed ID: 31431515 [TBL] [Abstract][Full Text] [Related]
13. Identification of novel reduced pyridinium derivatives as synthetic co-factors for the enzyme DT diaphorase (NAD(P)H dehydrogenase (quinone), EC 1.6.99.2). Friedlos F; Jarman M; Davies LC; Boland MP; Knox RJ Biochem Pharmacol; 1992 Jul; 44(1):25-31. PubMed ID: 1385952 [TBL] [Abstract][Full Text] [Related]
14. Characterization and partial purification of microsomal NAD(P)H:quinone oxidoreductases. Jaiswal AK Arch Biochem Biophys; 2000 Mar; 375(1):62-8. PubMed ID: 10683249 [TBL] [Abstract][Full Text] [Related]
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18. Catalytic properties of NAD(P)H:quinone acceptor oxidoreductase: study involving mouse, rat, human, and mouse-rat chimeric enzymes. Chen S; Knox R; Lewis AD; Friedlos F; Workman P; Deng PS; Fung M; Ebenstein D; Wu K; Tsai TM Mol Pharmacol; 1995 May; 47(5):934-9. PubMed ID: 7746280 [TBL] [Abstract][Full Text] [Related]
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20. NAD(P)H:quinone oxidoreductase 1 reduces the mutagenicity of DNA caused by NADPH:P450 reductase-activated metabolites of benzo(a)pyrene quinones. Joseph P; Jaiswal AK Br J Cancer; 1998 Mar; 77(5):709-19. PubMed ID: 9514048 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]