289 related articles for article (PubMed ID: 11050075)
1. Filamin (280-kDa actin-binding protein) is a caspase substrate and is also cleaved directly by the cytotoxic T lymphocyte protease granzyme B during apoptosis.
Browne KA; Johnstone RW; Jans DA; Trapani JA
J Biol Chem; 2000 Dec; 275(50):39262-6. PubMed ID: 11050075
[TBL] [Abstract][Full Text] [Related]
2. Efficient nuclear targeting of granzyme B and the nuclear consequences of apoptosis induced by granzyme B and perforin are caspase-dependent, but cell death is caspase-independent.
Trapani JA; Jans DA; Jans PJ; Smyth MJ; Browne KA; Sutton VR
J Biol Chem; 1998 Oct; 273(43):27934-8. PubMed ID: 9774406
[TBL] [Abstract][Full Text] [Related]
3. Cytotoxic T lymphocyte-assisted suicide. Caspase 3 activation is primarily the result of the direct action of granzyme B.
Atkinson EA; Barry M; Darmon AJ; Shostak I; Turner PC; Moyer RW; Bleackley RC
J Biol Chem; 1998 Aug; 273(33):21261-6. PubMed ID: 9694885
[TBL] [Abstract][Full Text] [Related]
4. Limited proteolysis of filamin is catalyzed by caspase-3 in U937 and Jurkat cells.
Umeda T; Kouchi Z; Kawahara H; Tomioka S; Sasagawa N; Maeda T; Sorimachi H; Ishiura S; Suzuki K
J Biochem; 2001 Oct; 130(4):535-42. PubMed ID: 11574073
[TBL] [Abstract][Full Text] [Related]
5. Granzyme B short-circuits the need for caspase 8 activity during granule-mediated cytotoxic T-lymphocyte killing by directly cleaving Bid.
Barry M; Heibein JA; Pinkoski MJ; Lee SF; Moyer RW; Green DR; Bleackley RC
Mol Cell Biol; 2000 Jun; 20(11):3781-94. PubMed ID: 10805722
[TBL] [Abstract][Full Text] [Related]
6. Functional dissociation of DeltaPsim and cytochrome c release defines the contribution of mitochondria upstream of caspase activation during granzyme B-induced apoptosis.
Waterhouse NJ; Sedelies KA; Sutton VR; Pinkoski MJ; Thia KY; Johnstone R; Bird PI; Green DR; Trapani JA
Cell Death Differ; 2006 Apr; 13(4):607-18. PubMed ID: 16167065
[TBL] [Abstract][Full Text] [Related]
7. Inhibition of CPP32-like proteases prevents granzyme B- and Fas-, but not granzyme A-based cytotoxicity exerted by CTL clones.
Anel A; Gamen S; Alava MA; Schmitt-Verhulst AM; PiƱeiro A; Naval J
J Immunol; 1997 Mar; 158(5):1999-2006. PubMed ID: 9036942
[TBL] [Abstract][Full Text] [Related]
8. Cytosolic delivery of granzyme B by bacterial toxins: evidence that endosomal disruption, in addition to transmembrane pore formation, is an important function of perforin.
Browne KA; Blink E; Sutton VR; Froelich CJ; Jans DA; Trapani JA
Mol Cell Biol; 1999 Dec; 19(12):8604-15. PubMed ID: 10567584
[TBL] [Abstract][Full Text] [Related]
9. Initiation of apoptosis by granzyme B requires direct cleavage of bid, but not direct granzyme B-mediated caspase activation.
Sutton VR; Davis JE; Cancilla M; Johnstone RW; Ruefli AA; Sedelies K; Browne KA; Trapani JA
J Exp Med; 2000 Nov; 192(10):1403-14. PubMed ID: 11085743
[TBL] [Abstract][Full Text] [Related]
10. Granzyme B-mediated death of pancreatic beta-cells requires the proapoptotic BH3-only molecule bid.
Estella E; McKenzie MD; Catterall T; Sutton VR; Bird PI; Trapani JA; Kay TW; Thomas HE
Diabetes; 2006 Aug; 55(8):2212-9. PubMed ID: 16873683
[TBL] [Abstract][Full Text] [Related]
11. Granzyme B-induced loss of mitochondrial inner membrane potential (Delta Psi m) and cytochrome c release are caspase independent.
Heibein JA; Barry M; Motyka B; Bleackley RC
J Immunol; 1999 Nov; 163(9):4683-93. PubMed ID: 10528165
[TBL] [Abstract][Full Text] [Related]
12. Serglycin-deficient cytotoxic T lymphocytes display defective secretory granule maturation and granzyme B storage.
Grujic M; Braga T; Lukinius A; Eloranta ML; Knight SD; Pejler G; Abrink M
J Biol Chem; 2005 Sep; 280(39):33411-8. PubMed ID: 16046402
[TBL] [Abstract][Full Text] [Related]
13. Perforin and granzyme B induce apoptosis in FasL-resistant colon carcinoma cells.
Vermijlen D; Froelich CJ; Luo D; Suarez-Huerta N; Robaye B; Wisse E
Cancer Immunol Immunother; 2001 Jun; 50(4):212-7. PubMed ID: 11459173
[TBL] [Abstract][Full Text] [Related]
14. Induction of rapid histone degradation by the cytotoxic T lymphocyte protease Granzyme A.
Zhang D; Pasternack MS; Beresford PJ; Wagner L; Greenberg AH; Lieberman J
J Biol Chem; 2001 Feb; 276(5):3683-90. PubMed ID: 11060286
[TBL] [Abstract][Full Text] [Related]
15. Granzymes (lymphocyte serine proteases): characterization with natural and synthetic substrates and inhibitors.
Kam CM; Hudig D; Powers JC
Biochim Biophys Acta; 2000 Mar; 1477(1-2):307-23. PubMed ID: 10708866
[TBL] [Abstract][Full Text] [Related]
16. Entry and trafficking of granzyme B in target cells during granzyme B-perforin-mediated apoptosis.
Pinkoski MJ; Hobman M; Heibein JA; Tomaselli K; Li F; Seth P; Froelich CJ; Bleackley RC
Blood; 1998 Aug; 92(3):1044-54. PubMed ID: 9680374
[TBL] [Abstract][Full Text] [Related]
17. Perforin and granzyme B of cytotoxic T lymphocyte mediate apoptosis irrespective of Helicobacter pylori infection: possible act as a trigger of peptic ulcer formation.
Ohara T; Morishita T; Suzuki H; Masaoka T; Ishii H
Hepatogastroenterology; 2003; 50(54):1774-9. PubMed ID: 14696402
[TBL] [Abstract][Full Text] [Related]
18. Cytotoxic T-cell-derived granzyme B activates the apoptotic protease ICE-LAP3.
Chinnaiyan AM; Hanna WL; Orth K; Duan H; Poirier GG; Froelich CJ; Dixit VM
Curr Biol; 1996 Jul; 6(7):897-9. PubMed ID: 8805307
[TBL] [Abstract][Full Text] [Related]
19. The human homologue of the yeast polyubiquitination factor Ufd2p is cleaved by caspase 6 and granzyme B during apoptosis.
Mahoney JA; Odin JA; White SM; Shaffer D; Koff A; Casciola-Rosen L; Rosen A
Biochem J; 2002 Feb; 361(Pt 3):587-95. PubMed ID: 11802788
[TBL] [Abstract][Full Text] [Related]
20. Granzyme M mediates a novel form of perforin-dependent cell death.
Kelly JM; Waterhouse NJ; Cretney E; Browne KA; Ellis S; Trapani JA; Smyth MJ
J Biol Chem; 2004 May; 279(21):22236-42. PubMed ID: 15028722
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]