BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

253 related articles for article (PubMed ID: 11054408)

  • 1. Thrombopoietin induces phosphoinositol 3-kinase activation through SHP2, Gab, and insulin receptor substrate proteins in BAF3 cells and primary murine megakaryocytes.
    Miyakawa Y; Rojnuckarin P; Habib T; Kaushansky K
    J Biol Chem; 2001 Jan; 276(4):2494-502. PubMed ID: 11054408
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Role of Gab proteins in phosphatidylinositol 3-kinase activation by thrombopoietin (Tpo).
    Bouscary D; Lecoq-Lafon C; Chrétien S; Zompi S; Fichelson S; Muller O; Porteu F; Dusanter-Fourt I; Gisselbrecht S; Mayeux P; Lacombe C
    Oncogene; 2001 Apr; 20(18):2197-204. PubMed ID: 11402314
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The roles of phosphatidylinositol 3-kinase and protein kinase Czeta for thrombopoietin-induced mitogen-activated protein kinase activation in primary murine megakaryocytes.
    Rojnuckarin P; Miyakawa Y; Fox NE; Deou J; Daum G; Kaushansky K
    J Biol Chem; 2001 Nov; 276(44):41014-22. PubMed ID: 11535599
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Receptor-specific regulation of phosphatidylinositol 3'-kinase activation by the protein tyrosine phosphatase Shp2.
    Zhang SQ; Tsiaras WG; Araki T; Wen G; Minichiello L; Klein R; Neel BG
    Mol Cell Biol; 2002 Jun; 22(12):4062-72. PubMed ID: 12024020
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Thrombopoietin (TPO) induces c-myc expression through a PI3K- and MAPK-dependent pathway that is not mediated by Akt, PKCzeta or mTOR in TPO-dependent cell lines and primary megakaryocytes.
    Chanprasert S; Geddis AE; Barroga C; Fox NE; Kaushansky K
    Cell Signal; 2006 Aug; 18(8):1212-8. PubMed ID: 16380230
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Erythropoietin induces the tyrosine phosphorylation of GAB1 and its association with SHC, SHP2, SHIP, and phosphatidylinositol 3-kinase.
    Lecoq-Lafon C; Verdier F; Fichelson S; Chrétien S; Gisselbrecht S; Lacombe C; Mayeux P
    Blood; 1999 Apr; 93(8):2578-85. PubMed ID: 10194437
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Engagement of Gab1 and Gab2 in erythropoietin signaling.
    Wickrema A; Uddin S; Sharma A; Chen F; Alsayed Y; Ahmad S; Sawyer ST; Krystal G; Yi T; Nishada K; Hibi M; Hirano T; Platanias LC
    J Biol Chem; 1999 Aug; 274(35):24469-74. PubMed ID: 10455108
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Lnk inhibits Tpo-mpl signaling and Tpo-mediated megakaryocytopoiesis.
    Tong W; Lodish HF
    J Exp Med; 2004 Sep; 200(5):569-80. PubMed ID: 15337790
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Thrombopoietin-induced activation of the mitogen-activated protein kinase (MAPK) pathway in normal megakaryocytes: role in endomitosis.
    Rojnuckarin P; Drachman JG; Kaushansky K
    Blood; 1999 Aug; 94(4):1273-82. PubMed ID: 10438715
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Signaling complexes and protein-protein interactions involved in the activation of the Ras and phosphatidylinositol 3-kinase pathways by the c-Ret receptor tyrosine kinase.
    Besset V; Scott RP; Ibáñez CF
    J Biol Chem; 2000 Dec; 275(50):39159-66. PubMed ID: 10995764
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A critical role for phosphoinositide 3-kinase upstream of Gab1 and SHP2 in the activation of ras and mitogen-activated protein kinases by epidermal growth factor.
    Yart A; Laffargue M; Mayeux P; Chretien S; Peres C; Tonks N; Roche S; Payrastre B; Chap H; Raynal P
    J Biol Chem; 2001 Mar; 276(12):8856-64. PubMed ID: 11134009
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Phosphatidylinositol 3-kinase is necessary but not sufficient for thrombopoietin-induced proliferation in engineered Mpl-bearing cell lines as well as in primary megakaryocytic progenitors.
    Geddis AE; Fox NE; Kaushansky K
    J Biol Chem; 2001 Sep; 276(37):34473-9. PubMed ID: 11418622
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Scaffolding protein Gab2 mediates differentiation signaling downstream of Fms receptor tyrosine kinase.
    Liu Y; Jenkins B; Shin JL; Rohrschneider LR
    Mol Cell Biol; 2001 May; 21(9):3047-56. PubMed ID: 11287610
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Interleukin-3 induces association of the protein-tyrosine phosphatase SHP2 and phosphatidylinositol 3-kinase with a 100-kDa tyrosine-phosphorylated protein in hemopoietic cells.
    Craddock BL; Welham MJ
    J Biol Chem; 1997 Nov; 272(46):29281-9. PubMed ID: 9361008
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The c-Mpl ligand (thrombopoietin) stimulates tyrosine phosphorylation of Jak2, Shc, and c-Mpl.
    Drachman JG; Griffin JD; Kaushansky K
    J Biol Chem; 1995 Mar; 270(10):4979-82. PubMed ID: 7534285
    [TBL] [Abstract][Full Text] [Related]  

  • 16. PI3K/Akt/FOXO3a pathway contributes to thrombopoietin-induced proliferation of primary megakaryocytes in vitro and in vivo via modulation of p27(Kip1).
    Nakao T; Geddis AE; Fox NE; Kaushansky K
    Cell Cycle; 2008 Jan; 7(2):257-66. PubMed ID: 18256550
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Gab-family adapter proteins act downstream of cytokine and growth factor receptors and T- and B-cell antigen receptors.
    Nishida K; Yoshida Y; Itoh M; Fukada T; Ohtani T; Shirogane T; Atsumi T; Takahashi-Tezuka M; Ishihara K; Hibi M; Hirano T
    Blood; 1999 Mar; 93(6):1809-16. PubMed ID: 10068651
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Lyn tyrosine kinase regulates thrombopoietin-induced proliferation of hematopoietic cell lines and primary megakaryocytic progenitors.
    Lannutti BJ; Drachman JG
    Blood; 2004 May; 103(10):3736-43. PubMed ID: 14726379
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Regulation of platelet activation in vitro by the c-Mpl ligand, thrombopoietin.
    Chen J; Herceg-Harjacek L; Groopman JE; Grabarek J
    Blood; 1995 Dec; 86(11):4054-62. PubMed ID: 7492761
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The Gab1 docking protein links the b cell antigen receptor to the phosphatidylinositol 3-kinase/Akt signaling pathway and to the SHP2 tyrosine phosphatase.
    Ingham RJ; Santos L; Dang-Lawson M; Holgado-Madruga M; Dudek P; Maroun CR; Wong AJ; Matsuuchi L; Gold MR
    J Biol Chem; 2001 Apr; 276(15):12257-65. PubMed ID: 11278704
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.