108 related articles for article (PubMed ID: 11055341)
1. Synthesis and enzymatic evaluation of a P1 arginine aminocoumarin substrate library for trypsin-like serine proteases.
Edwards PD; Mauger RC; Cottrell KM; Morris FX; Pine KK; Sylvester MA; Scott CW; Furlong ST
Bioorg Med Chem Lett; 2000 Oct; 10(20):2291-4. PubMed ID: 11055341
[TBL] [Abstract][Full Text] [Related]
2. Synthesis and physical characterization of a P1 arginine combinatorial library, and its application to the determination of the substrate specificity of serine peptidases.
Furlong ST; Mauger RC; Strimpler AM; Liu YP; Morris FX; Edwards PD
Bioorg Med Chem; 2002 Nov; 10(11):3637-47. PubMed ID: 12213480
[TBL] [Abstract][Full Text] [Related]
3. Synthesis of positional-scanning libraries of fluorogenic peptide substrates to define the extended substrate specificity of plasmin and thrombin.
Backes BJ; Harris JL; Leonetti F; Craik CS; Ellman JA
Nat Biotechnol; 2000 Feb; 18(2):187-93. PubMed ID: 10657126
[TBL] [Abstract][Full Text] [Related]
4. Analysis of the substrate specificity of Factor VII activating protease (FSAP) and design of specific and sensitive peptide substrates.
Kara E; Manna D; Løset GÅ; Schneider EL; Craik CS; Kanse S
Thromb Haemost; 2017 Aug; 117(9):1750-1760. PubMed ID: 28726978
[TBL] [Abstract][Full Text] [Related]
5. A strategy to profile prime and non-prime proteolytic substrate specificity.
Petrassi HM; Williams JA; Li J; Tumanut C; Ek J; Nakai T; Masick B; Backes BJ; Harris JL
Bioorg Med Chem Lett; 2005 Jun; 15(12):3162-6. PubMed ID: 15878267
[TBL] [Abstract][Full Text] [Related]
6. Peptide microarrays for the determination of protease substrate specificity.
Salisbury CM; Maly DJ; Ellman JA
J Am Chem Soc; 2002 Dec; 124(50):14868-70. PubMed ID: 12475327
[TBL] [Abstract][Full Text] [Related]
7. Mapping the active sites of bovine thrombin, factor IXa, factor Xa, factor XIa, factor XIIa, plasma kallikrein, and trypsin with amino acid and peptide thioesters: development of new sensitive substrates.
McRae BJ; Kurachi K; Heimark RL; Fujikawa K; Davie EW; Powers JC
Biochemistry; 1981 Dec; 20(25):7196-206. PubMed ID: 6976185
[TBL] [Abstract][Full Text] [Related]
8. Mapping the S' subsites of serine proteases using acyl transfer to mixtures of peptide nucleophiles.
Schellenberger V; Turck CW; Hedstrom L; Rutter WJ
Biochemistry; 1993 Apr; 32(16):4349-53. PubMed ID: 8476865
[TBL] [Abstract][Full Text] [Related]
9. Hepatocyte growth factor is a preferred in vitro substrate for human hepsin, a membrane-anchored serine protease implicated in prostate and ovarian cancers.
Herter S; Piper DE; Aaron W; Gabriele T; Cutler G; Cao P; Bhatt AS; Choe Y; Craik CS; Walker N; Meininger D; Hoey T; Austin RJ
Biochem J; 2005 Aug; 390(Pt 1):125-36. PubMed ID: 15839837
[TBL] [Abstract][Full Text] [Related]
10. Substrate specificity determination of mouse implantation serine proteinase and human kallikrein-related peptidase 6 by phage display.
Sharma N; Oikonomopoulou K; Ito K; Renaux B; Diamandis EP; Hollenberg MD; Rancourt DE
Biol Chem; 2008 Aug; 389(8):1097-105. PubMed ID: 18979633
[TBL] [Abstract][Full Text] [Related]
11. Rapid and general profiling of protease specificity by using combinatorial fluorogenic substrate libraries.
Harris JL; Backes BJ; Leonetti F; Mahrus S; Ellman JA; Craik CS
Proc Natl Acad Sci U S A; 2000 Jul; 97(14):7754-9. PubMed ID: 10869434
[TBL] [Abstract][Full Text] [Related]
12. α-Ketobenzothiazole Serine Protease Inhibitors of Aberrant HGF/c-MET and MSP/RON Kinase Pathway Signaling in Cancer.
Han Z; Harris PK; Karmakar P; Kim T; Owusu BY; Wildman SA; Klampfer L; Janetka JW
ChemMedChem; 2016 Mar; 11(6):585-99. PubMed ID: 26889658
[TBL] [Abstract][Full Text] [Related]
13. New inhibitors of thrombin and other trypsin-like proteases: hydrogen bonding of an aromatic cyano group with a backbone amide of the P1 binding site replaces binding of a basic side chain.
Lee SL; Alexander RS; Smallwood A; Trievel R; Mersinger L; Weber PC; Kettner C
Biochemistry; 1997 Oct; 36(43):13180-6. PubMed ID: 9341205
[TBL] [Abstract][Full Text] [Related]
14. Rapid identification of substrates for novel proteases using a combinatorial peptide library.
Rossé G; Kueng E; Page MG; Schauer-Vukasinovic V; Giller T; Lahm HW; Hunziker P; Schlatter D
J Comb Chem; 2000; 2(5):461-6. PubMed ID: 11029171
[TBL] [Abstract][Full Text] [Related]
15. Characterization of structural determinants of granzyme B reveals potent mediators of extended substrate specificity.
Ruggles SW; Fletterick RJ; Craik CS
J Biol Chem; 2004 Jul; 279(29):30751-9. PubMed ID: 15123647
[TBL] [Abstract][Full Text] [Related]
16. Active site mapping of trypsin, thrombin and matriptase-2 by sulfamoyl benzamidines.
Dosa S; Stirnberg M; Lülsdorff V; Häußler D; Maurer E; Gütschow M
Bioorg Med Chem; 2012 Nov; 20(21):6489-505. PubMed ID: 23026080
[TBL] [Abstract][Full Text] [Related]
17. The role of the insertion loop around tryptophan 148 in tthe activity of thrombin.
DiBella EE; Scheraga HA
Biochemistry; 1996 Apr; 35(14):4427-33. PubMed ID: 8605192
[TBL] [Abstract][Full Text] [Related]
18. Molecular design and characterization of an alpha-thrombin inhibitor containing a novel P1 moiety.
Malikayil JA; Burkhart JP; Schreuder HA; Broersma RJ; Tardif C; Kutcher LW; Mehdi S; Schatzman GL; Neises B; Peet NP
Biochemistry; 1997 Feb; 36(5):1034-40. PubMed ID: 9033393
[TBL] [Abstract][Full Text] [Related]
19. Catalytic properties of serine proteases. 2. Comparison between human urinary kallikrein and human urokinase, bovine beta-trypsin, bovine thrombin, and bovine alpha-chymotrypsin.
Ascenzi P; Menegatti E; Guarneri M; Bortolotti F; Antonini E
Biochemistry; 1982 May; 21(10):2483-90. PubMed ID: 7046788
[TBL] [Abstract][Full Text] [Related]
20. Solid-phase synthesis of a library based on biphenyl-containing trypsin-like serine protease inhibitors.
Shi S; Zhu S; Gerritz SW; Rachwal B; Ruan Z; Hutchins R; Kakarla R; Sofia MJ; Sutton J; Cheney D
Bioorg Med Chem Lett; 2009 Nov; 19(22):6477-80. PubMed ID: 19804972
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
