These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

129 related articles for article (PubMed ID: 11055349)

  • 1. The design and synthesis of novel NK1/NK2 dual antagonists.
    Reichard GA; Ball ZT; Aslanian R; Anthes JC; Shih NY; Piwinski JJ
    Bioorg Med Chem Lett; 2000 Oct; 10(20):2329-32. PubMed ID: 11055349
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Discovery of novel, orally active dual NK1/NK2 antagonists.
    Bernstein PR; Aharony D; Albert JS; Andisik D; Barthlow HG; Bialecki R; Davenport T; Dedinas RF; Dembofsky BT; Koether G; Kosmider BJ; Kirkland K; Ohnmacht CJ; Potts W; Rumsey WL; Shen L; Shenvi A; Sherwood S; Stollman D; Russell K
    Bioorg Med Chem Lett; 2001 Oct; 11(20):2769-73. PubMed ID: 11591520
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Synthesis and structure-activity relationships of oxime neurokinin antagonists: discovery of potent arylamides.
    Shih NY; Albanese M; Anthes JC; Carruthers NI; Grice CA; Lin L; Mangiaracina P; Reichard GA; Schwerdt J; Seidl V; Wong SC; Piwinski JJ
    Bioorg Med Chem Lett; 2002 Jan; 12(2):141-5. PubMed ID: 11755340
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Spiro-substituted piperidines as neurokinin receptor antagonists. I. Design and synthesis of (+/-)-N-[2-(3,4-dichlorophenyl)-4-(spiro [isobenzofuran-1(3H),4'piperidin]-1'-yl)butyl]-N-methylbenzamide, YM-35375, as a new lead compound for novel neurokinin receptor antagonists.
    Kubota H; Fujii M; Ikeda K; Takeuchi M; Shibanuma T; Isomura Y
    Chem Pharm Bull (Tokyo); 1998 Feb; 46(2):351-4. PubMed ID: 9501470
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Spiro-substituted piperidines as neurokinin receptor antagonists. III. Synthesis of (+/-)-N-[2-(3,4-dichlorophenyl)-4-(spiro-substituted piperidin-1'-yl)butyl]-N-methylbenzamides and evaluation of NK1-NK2 dual antagonistic activities.
    Kubota H; Kakefuda A; Okamoto Y; Fujii M; Yamamoto O; Yamagiwa Y; Orita M; Ikeda K; Takeuchi M; Shibanuma T; Isomura Y
    Chem Pharm Bull (Tokyo); 1998 Oct; 46(10):1538-44. PubMed ID: 9810691
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Synthesis of substituted 4(Z)-(methoxyimino)pentyl-1-piperidines as dual NK1/NK2 inhibitors.
    Ting PC; Lee JF; Anthes JC; Shih NY; Piwinski JJ
    Bioorg Med Chem Lett; 2001 Feb; 11(4):491-4. PubMed ID: 11229755
    [TBL] [Abstract][Full Text] [Related]  

  • 7. 4-Alkylpiperidines related to SR-48968: potent antagonists of the neurokinin-2 (NK2) receptor.
    Jacobs RT; Shenvi AB; Mauger RC; Ulatowski TG; Aharony D; Buckner CK
    Bioorg Med Chem Lett; 1998 Jul; 8(14):1935-40. PubMed ID: 9873462
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The non-peptide tachykinin NK1- and NK2-receptor antagonists SR 140333 and SR 48968 prevent castor-oil induced diarrhea in rats.
    Croci T; Emonds-Alt X; Le Fur G; Maffrand JP; Manara L
    Acta Physiol Hung; 1996; 84(3):273-4. PubMed ID: 9219603
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Design and synthesis of substituted N-methylbenzamide analogues derived from SR 48,968 as neurokinin-2 receptor antagonists.
    Huang SC; Undem B; Korlipara V
    Bioorg Med Chem Lett; 2004 Sep; 14(18):4779-82. PubMed ID: 15324907
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Increased blocking activity of combined tachykinin NK1- and NK2-receptor antagonists on hyperventilation-induced bronchoconstriction in the guinea pig.
    Corboz MR; Fernandez X; Hey JA
    Pulm Pharmacol Ther; 2008; 21(1):67-72. PubMed ID: 17239637
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Effects of central administration of tachykinin receptor agonists and antagonists on plus-maze behavior in mice.
    Teixeira RM; Santos AR; Ribeiro SJ; Calixto JB; Rae GA; De Lima TC
    Eur J Pharmacol; 1996 Sep; 311(1):7-14. PubMed ID: 8884230
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Structure-activity relationships of oxime neurokinin antagonists: oxime modifications.
    Reichard GA; Spitler J; Aslanian R; Mutahi Mw; Shih NY; Lin L; Ting PC; Anthes JC; Piwinski JJ
    Bioorg Med Chem Lett; 2002 Mar; 12(5):833-6. PubMed ID: 11859013
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Tachykinin NK1 and NK2 receptor-mediated control of peristaltic propulsion in the guinea-pig small intestine in vitro.
    Holzer P; Lippe IT; Heinemann A; Barthó L
    Neuropharmacology; 1998; 37(1):131-8. PubMed ID: 9680266
    [TBL] [Abstract][Full Text] [Related]  

  • 14. L-tryptophan urea amides as NK1/NK2 dual antagonists.
    Qi H; Shah SK; Cascieri MA; Sadowski SJ; MaCcoss M
    Bioorg Med Chem Lett; 1998 Aug; 8(16):2259-62. PubMed ID: 9873524
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Identification of both NK1 and NK2 receptors in guinea-pig airways.
    McKee KT; Millar L; Rodger IW; Metters KM
    Br J Pharmacol; 1993 Oct; 110(2):693-700. PubMed ID: 7694756
    [TBL] [Abstract][Full Text] [Related]  

  • 16. SR 48968 specifically depresses neurokinin A- vs. substance P-induced hyperalgesia in a nociceptive withdrawal reflex.
    Yashpal K; Hui-Chan CW; Henry JL
    Eur J Pharmacol; 1996 Jul; 308(1):41-8. PubMed ID: 8836630
    [TBL] [Abstract][Full Text] [Related]  

  • 17. NK2 receptors mediate tachykinin-induced contractions of rat uterus during the oestrous cycle.
    Moodley N; Lau WA; Pennefather JN; Story ME; Fisher L
    Eur J Pharmacol; 1999 Jul; 376(1-2):53-60. PubMed ID: 10440089
    [TBL] [Abstract][Full Text] [Related]  

  • 18. N-[(R,R)-(E)-1-(4-chloro-benzyl)-3-(2-oxo-azepan-3-ylcarbamoyl)-allyl]-N-methyl-3,5-bis-trifluoromethyl-benzamide: an orally active neurokinin NK1/NK2 antagonist.
    Gerspacher M; von Sprecher A; Mah R; Anderson GP; Bertrand C; Subramanian N; Hauser K; Ball HA
    Bioorg Med Chem Lett; 2000 Jul; 10(13):1467-70. PubMed ID: 10888334
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Prevention by the tachykinin NK2 receptor antagonist, SR 48968, of antigen-induced airway hyperresponsiveness in sensitized guinea-pigs.
    Boichot E; Germain N; Lagente V; Advenier C
    Br J Pharmacol; 1995 Jan; 114(2):259-61. PubMed ID: 7881725
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Two nonpeptide tachykinin antagonists act through epitopes on corresponding segments of the NK1 and NK2 receptors.
    Gether U; Yokota Y; Emonds-Alt X; Brelière JC; Lowe JA; Snider RM; Nakanishi S; Schwartz TW
    Proc Natl Acad Sci U S A; 1993 Jul; 90(13):6194-8. PubMed ID: 7687062
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.