133 related articles for article (PubMed ID: 11055357)
1. Optimising inhibitors of trypanothione reductase using solid-phase chemistry.
Chitkul B; Bradley M
Bioorg Med Chem Lett; 2000 Oct; 10(20):2367-9. PubMed ID: 11055357
[TBL] [Abstract][Full Text] [Related]
2. Polyamines with N-(3-phenylpropyl) substituents are effective competitive inhibitors of trypanothione reductase and trypanocidal agents.
Li Z; Fennie MW; Ganem B; Hancock MT; Kobaslija M; Rattendi D; Bacchi CJ; O'Sullivan MC
Bioorg Med Chem Lett; 2001 Jan; 11(2):251-4. PubMed ID: 11206471
[TBL] [Abstract][Full Text] [Related]
3. Benzofuranyl 3,5-bis-polyamine derivatives as time-dependent inhibitors of trypanothione reductase.
Hamilton CJ; Saravanamuthu A; Fairlamb AH; Eggleston IM
Bioorg Med Chem; 2003 Aug; 11(17):3683-93. PubMed ID: 12901914
[TBL] [Abstract][Full Text] [Related]
4. Comparison of resin and solution screening methodologies in combinatorial chemistry and the identification of a 100 nM inhibitor of trypanothione reductase.
Smith HK; Bradley M
J Comb Chem; 1999; 1(4):326-32. PubMed ID: 10748738
[TBL] [Abstract][Full Text] [Related]
5. Kukoamine A and other hydrophobic acylpolyamines: potent and selective inhibitors of Crithidia fasciculata trypanothione reductase.
Ponasik JA; Strickland C; Faerman C; Savvides S; Karplus PA; Ganem B
Biochem J; 1995 Oct; 311 ( Pt 2)(Pt 2):371-5. PubMed ID: 7487870
[TBL] [Abstract][Full Text] [Related]
6. Structure-activity relationships in 2-aminodiphenylsulfides against trypanothione reductase from Trypanosoma cruzi.
Girault S; Davioud-Charvet E; Salmon L; Berecibar A; Debreu MA; Sergheraert C
Bioorg Med Chem Lett; 1998 May; 8(10):1175-80. PubMed ID: 9871730
[TBL] [Abstract][Full Text] [Related]
7. Phenothiazine inhibitors of trypanothione reductase as potential antitrypanosomal and antileishmanial drugs.
Chan C; Yin H; Garforth J; McKie JH; Jaouhari R; Speers P; Douglas KT; Rock PJ; Yardley V; Croft SL; Fairlamb AH
J Med Chem; 1998 Jan; 41(2):148-56. PubMed ID: 9457238
[TBL] [Abstract][Full Text] [Related]
8. Improved tricyclic inhibitors of trypanothione reductase by screening and chemical synthesis.
Richardson JL; Nett IR; Jones DC; Abdille MH; Gilbert IH; Fairlamb AH
ChemMedChem; 2009 Aug; 4(8):1333-40. PubMed ID: 19557801
[TBL] [Abstract][Full Text] [Related]
9. Dibenzosuberyl substituted polyamines and analogs of clomipramine as effective inhibitors of trypanothione reductase; molecular docking, and assessment of trypanocidal activities.
O'Sullivan MC; Durham TB; Valdes HE; Dauer KL; Karney NJ; Forrestel AC; Bacchi CJ; Baker JF
Bioorg Med Chem; 2015 Mar; 23(5):996-1010. PubMed ID: 25661449
[TBL] [Abstract][Full Text] [Related]
10. Inhibitors of trypanothione reductase as potential antitrypanosomal drugs.
Chan C; Yin H; Garforth J; McKie JH; Jaouhari RA; Douglas KT; Fairlamb AH; Croft SL
Biochem Soc Trans; 1995 Nov; 23(4):511S. PubMed ID: 8654696
[No Abstract] [Full Text] [Related]
11. Structural analysis and molecular docking of trypanocidal aryloxy-quinones in trypanothione and glutathione reductases: a comparison with biochemical data.
Vera B; Vázquez K; Mascayano C; Tapia RA; Espinosa V; Soto-Delgado J; Salas CO; Paulino M
J Biomol Struct Dyn; 2017 Jun; 35(8):1785-1803. PubMed ID: 27232454
[TBL] [Abstract][Full Text] [Related]
12. Synthesis and evaluation of 1-(1-(Benzo[b]thiophen-2-yl)cyclohexyl)piperidine (BTCP) analogues as inhibitors of trypanothione reductase.
Patterson S; Jones DC; Shanks EJ; Frearson JA; Gilbert IH; Wyatt PG; Fairlamb AH
ChemMedChem; 2009 Aug; 4(8):1341-53. PubMed ID: 19557802
[TBL] [Abstract][Full Text] [Related]
13. (2,2':6',2"-Terpyridine)platinum(II) complexes are irreversible inhibitors of Trypanosoma cruzi trypanothione reductase but not of human glutathione reductase.
Bonse S; Richards JM; Ross SA; Lowe G; Krauth-Siegel RL
J Med Chem; 2000 Dec; 43(25):4812-21. PubMed ID: 11123991
[TBL] [Abstract][Full Text] [Related]
14. Mechanism of inhibition of trypanothione reductase and glutathione reductase by trivalent organic arsenicals.
Cunningham ML; Zvelebil MJ; Fairlamb AH
Eur J Biochem; 1994 Apr; 221(1):285-95. PubMed ID: 8168518
[TBL] [Abstract][Full Text] [Related]
15. Peptoid inhibition of trypanothione reductase as a potential antitrypanosomal and antileishmanial drug lead.
Chan C; Yin H; McKie JH; Fairlamb AH; Douglas KT
Amino Acids; 2002 Jun; 22(4):297-308. PubMed ID: 12107758
[TBL] [Abstract][Full Text] [Related]
16. 2- and 3-substituted 1,4-naphthoquinone derivatives as subversive substrates of trypanothione reductase and lipoamide dehydrogenase from Trypanosoma cruzi: synthesis and correlation between redox cycling activities and in vitro cytotoxicity.
Salmon-Chemin L; Buisine E; Yardley V; Kohler S; Debreu MA; Landry V; Sergheraert C; Croft SL; Krauth-Siegel RL; Davioud-Charvet E
J Med Chem; 2001 Feb; 44(4):548-65. PubMed ID: 11170645
[TBL] [Abstract][Full Text] [Related]
17. Coupling of a competitive and an irreversible ligand generates mixed type inhibitors of Trypanosoma cruzi trypanothione reductase.
Inhoff O; Richards JM; Brîet JW; Lowe G; Krauth-Siegel RL
J Med Chem; 2002 Sep; 45(20):4524-30. PubMed ID: 12238931
[TBL] [Abstract][Full Text] [Related]
18. Trypanothione Reductase and Superoxide Dismutase as Current Drug Targets for Trypanosoma cruzi: An Overview of Compounds with Activity against Chagas Disease.
Beltran-Hortelano I; Perez-Silanes S; Galiano S
Curr Med Chem; 2017 May; 24(11):1066-1138. PubMed ID: 28025938
[TBL] [Abstract][Full Text] [Related]
19. A general approach to the synthesis of polyamine linked-monoindolylmaleimides, a new series of trypanothione reductase inhibitors.
Salmon L; Landry V; Melnyk O; Maes L; Sergheraert C; Davioud-Charvet E
Chem Pharm Bull (Tokyo); 1998 Apr; 46(4):707-10. PubMed ID: 9579046
[TBL] [Abstract][Full Text] [Related]
20. Time-dependent inhibitors of trypanothione reductase: analogues of the spermidine alkaloid lunarine and related natural products.
Hamilton CJ; Saravanamuthu A; Poupat C; Fairlamb AH; Eggleston IM
Bioorg Med Chem; 2006 Apr; 14(7):2266-78. PubMed ID: 16303308
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]