BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

491 related articles for article (PubMed ID: 11058584)

  • 1. Analysis of biological effects and signaling properties of Flt-1 (VEGFR-1) and KDR (VEGFR-2). A reassessment using novel receptor-specific vascular endothelial growth factor mutants.
    Gille H; Kowalski J; Li B; LeCouter J; Moffat B; Zioncheck TF; Pelletier N; Ferrara N
    J Biol Chem; 2001 Feb; 276(5):3222-30. PubMed ID: 11058584
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Placenta growth factor stimulates MAP kinase and mitogenicity but not phospholipase C-gamma and migration of endothelial cells expressing Flt 1.
    Landgren E; Schiller P; Cao Y; Claesson-Welsh L
    Oncogene; 1998 Jan; 16(3):359-67. PubMed ID: 9467961
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Vascular permeability factor (VPF)/vascular endothelial growth factor (VEGF) peceptor-1 down-modulates VPF/VEGF receptor-2-mediated endothelial cell proliferation, but not migration, through phosphatidylinositol 3-kinase-dependent pathways.
    Zeng H; Dvorak HF; Mukhopadhyay D
    J Biol Chem; 2001 Jul; 276(29):26969-79. PubMed ID: 11350975
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A repressor sequence in the juxtamembrane domain of Flt-1 (VEGFR-1) constitutively inhibits vascular endothelial growth factor-dependent phosphatidylinositol 3'-kinase activation and endothelial cell migration.
    Gille H; Kowalski J; Yu L; Chen H; Pisabarro MT; Davis-Smyth T; Ferrara N
    EMBO J; 2000 Aug; 19(15):4064-73. PubMed ID: 10921887
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Reactive oxygen species as downstream mediators of angiogenic signaling by vascular endothelial growth factor receptor-2/KDR.
    Colavitti R; Pani G; Bedogni B; Anzevino R; Borrello S; Waltenberger J; Galeotti T
    J Biol Chem; 2002 Feb; 277(5):3101-8. PubMed ID: 11719508
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Tyrosine residues 951 and 1059 of vascular endothelial growth factor receptor-2 (KDR) are essential for vascular permeability factor/vascular endothelial growth factor-induced endothelium migration and proliferation, respectively.
    Zeng H; Sanyal S; Mukhopadhyay D
    J Biol Chem; 2001 Aug; 276(35):32714-9. PubMed ID: 11435426
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Utilization of distinct signaling pathways by receptors for vascular endothelial cell growth factor and other mitogens in the induction of endothelial cell proliferation.
    Wu LW; Mayo LD; Dunbar JD; Kessler KM; Baerwald MR; Jaffe EA; Wang D; Warren RS; Donner DB
    J Biol Chem; 2000 Feb; 275(7):5096-103. PubMed ID: 10671553
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Roles of two VEGF receptors, Flt-1 and KDR, in the signal transduction of VEGF effects in human vascular endothelial cells.
    Kanno S; Oda N; Abe M; Terai Y; Ito M; Shitara K; Tabayashi K; Shibuya M; Sato Y
    Oncogene; 2000 Apr; 19(17):2138-46. PubMed ID: 10815805
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Vascular endothelial cell growth factor-driven endothelial tube formation is mediated by vascular endothelial cell growth factor receptor-2, a kinase insert domain-containing receptor.
    Yang S; Xin X; Zlot C; Ingle G; Fuh G; Li B; Moffat B; de Vos AM; Gerritsen ME
    Arterioscler Thromb Vasc Biol; 2001 Dec; 21(12):1934-40. PubMed ID: 11742867
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Vascular endothelial growth factor receptor-1 modulates vascular endothelial growth factor-mediated angiogenesis via nitric oxide.
    Bussolati B; Dunk C; Grohman M; Kontos CD; Mason J; Ahmed A
    Am J Pathol; 2001 Sep; 159(3):993-1008. PubMed ID: 11549592
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Properties of two VEGF receptors, Flt-1 and KDR, in signal transduction.
    Sato Y; Kanno S; Oda N; Abe M; Ito M; Shitara K; Shibuya M
    Ann N Y Acad Sci; 2000 May; 902():201-5; discussion 205-7. PubMed ID: 10865839
    [TBL] [Abstract][Full Text] [Related]  

  • 12. KDR (VEGF receptor 2) is the major mediator for the hypotensive effect of VEGF.
    Li B; Ogasawara AK; Yang R; Wei W; He GW; Zioncheck TF; Bunting S; de Vos AM; Jin H
    Hypertension; 2002 Jun; 39(6):1095-100. PubMed ID: 12052848
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Complete inhibition of vascular endothelial growth factor (VEGF) activities with a bifunctional diabody directed against both VEGF kinase receptors, fms-like tyrosine kinase receptor and kinase insert domain-containing receptor.
    Lu D; Jimenez X; Zhang H; Wu Y; Bohlen P; Witte L; Zhu Z
    Cancer Res; 2001 Oct; 61(19):7002-8. PubMed ID: 11585724
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Vascular endothelial growth factor upregulates the expression of matrix metalloproteinases in vascular smooth muscle cells: role of flt-1.
    Wang H; Keiser JA
    Circ Res; 1998 Oct; 83(8):832-40. PubMed ID: 9776730
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Vascular endothelial growth factor induces expression of connective tissue growth factor via KDR, Flt1, and phosphatidylinositol 3-kinase-akt-dependent pathways in retinal vascular cells.
    Suzuma K; Naruse K; Suzuma I; Takahara N; Ueki K; Aiello LP; King GL
    J Biol Chem; 2000 Dec; 275(52):40725-31. PubMed ID: 11018037
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Heterotrimeric G alpha q/G alpha 11 proteins function upstream of vascular endothelial growth factor (VEGF) receptor-2 (KDR) phosphorylation in vascular permeability factor/VEGF signaling.
    Zeng H; Zhao D; Yang S; Datta K; Mukhopadhyay D
    J Biol Chem; 2003 Jun; 278(23):20738-45. PubMed ID: 12670961
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Identification of vascular endothelial growth factor determinants for binding KDR and FLT-1 receptors. Generation of receptor-selective VEGF variants by site-directed mutagenesis.
    Keyt BA; Nguyen HV; Berleau LT; Duarte CM; Park J; Chen H; Ferrara N
    J Biol Chem; 1996 Mar; 271(10):5638-46. PubMed ID: 8621427
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Src kinase becomes preferentially associated with the VEGFR, KDR/Flk-1, following VEGF stimulation of vascular endothelial cells.
    Chou MT; Wang J; Fujita DJ
    BMC Biochem; 2002 Dec; 3():32. PubMed ID: 12509223
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Possible involvement of VEGF-FLT tyrosine kinase receptor system in normal and tumor angiogenesis.
    Shibuya M; Seetharam L; Ishii Y; Sawano A; Gotoh N; Matsushime H; Yamaguchi S
    Princess Takamatsu Symp; 1994; 24():162-70. PubMed ID: 8983073
    [TBL] [Abstract][Full Text] [Related]  

  • 20. A novel vascular endothelial growth factor encoded by Orf virus, VEGF-E, mediates angiogenesis via signalling through VEGFR-2 (KDR) but not VEGFR-1 (Flt-1) receptor tyrosine kinases.
    Meyer M; Clauss M; Lepple-Wienhues A; Waltenberger J; Augustin HG; Ziche M; Lanz C; Büttner M; Rziha HJ; Dehio C
    EMBO J; 1999 Jan; 18(2):363-74. PubMed ID: 9889193
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 25.