159 related articles for article (PubMed ID: 11059788)
1. A modified p53 overcomes mdm2-mediated oncogenic transformation: a potential cancer therapeutic agent.
Lin J; Jin X; Page C; Sondak VK; Jiang G; Reynolds RK
Cancer Res; 2000 Oct; 60(20):5895-901. PubMed ID: 11059788
[TBL] [Abstract][Full Text] [Related]
2. Mdm2 ligase dead mutants did not act in a dominant negative manner to re-activate p53, but promoted tumor cell growth.
Swaroop M; Sun Y
Anticancer Res; 2003; 23(4):3167-74. PubMed ID: 12926050
[TBL] [Abstract][Full Text] [Related]
3. The mdm-2 oncogene can overcome wild-type p53 suppression of transformed cell growth.
Finlay CA
Mol Cell Biol; 1993 Jan; 13(1):301-6. PubMed ID: 8417333
[TBL] [Abstract][Full Text] [Related]
4. The p53 tumor suppressor gene and gene product.
Levine AJ
Princess Takamatsu Symp; 1989; 20():221-30. PubMed ID: 2488233
[TBL] [Abstract][Full Text] [Related]
5. Multiple lysine mutations in the C-terminus of p53 make it resistant to degradation mediated by MDM2 but not by human papillomavirus E6 and induce growth inhibition in MDM2-overexpressing cells.
Nakamura S; Roth JA; Mukhopadhyay T
Oncogene; 2002 Apr; 21(16):2605-10. PubMed ID: 11971195
[TBL] [Abstract][Full Text] [Related]
6. Cell-specific transcriptional activation of the mdm2-gene by ectopically expressed wild-type form of a temperature-sensitive mutant p53.
Knippschild U; Kolzau T; Deppert W
Oncogene; 1995 Aug; 11(4):683-90. PubMed ID: 7651732
[TBL] [Abstract][Full Text] [Related]
7. Exogenous wt-p53 protein is active in transformed cells but not in their non-transformed counterparts: implications for cancer gene therapy without tumor targeting.
D'Orazi G; Marchetti A; Crescenzi M; Coen S; Sacchi A; Soddu S
J Gene Med; 2000; 2(1):11-21. PubMed ID: 10765501
[TBL] [Abstract][Full Text] [Related]
8. The carboxy-terminal serine 392 phosphorylation site of human p53 is not required for wild-type activities.
Fiscella M; Zambrano N; Ullrich SJ; Unger T; Lin D; Cho B; Mercer WE; Anderson CW; Appella E
Oncogene; 1994 Nov; 9(11):3249-57. PubMed ID: 7936649
[TBL] [Abstract][Full Text] [Related]
9. The high levels of p53 present in adenovirus early region 1-transformed human cells do not cause up-regulation of MDM2 expression.
Grand RJ; Lecane PS; Owen D; Grant ML; Roberts S; Levine AJ; Gallimore PH
Virology; 1995 Jul; 210(2):323-34. PubMed ID: 7618270
[TBL] [Abstract][Full Text] [Related]
10. Deregulation of p53/p21Cip1/Waf1 pathway contributes to polyploidy and apoptosis of E1A+cHa-ras transformed cells after gamma-irradiation.
Bulavin DV; Tararova ND; Aksenov ND; Pospelov VA; Pospelova TV
Oncogene; 1999 Oct; 18(41):5611-9. PubMed ID: 10523840
[TBL] [Abstract][Full Text] [Related]
11. Suppression of the p300-dependent mdm2 negative-feedback loop induces the p53 apoptotic function.
Thomas A; White E
Genes Dev; 1998 Jul; 12(13):1975-85. PubMed ID: 9649502
[TBL] [Abstract][Full Text] [Related]
12. Defective p53 post-translational modification required for wild type p53 inactivation in malignant epithelial cells with mdm2 gene amplification.
Knights CD; Liu Y; Appella E; Kulesz-Martin M
J Biol Chem; 2003 Dec; 278(52):52890-900. PubMed ID: 14555661
[TBL] [Abstract][Full Text] [Related]
13. Resistance to p53-mediated growth suppression in human ovarian cancer cells retain endogenous wild-type p53.
Jin X; Burke W; Rothman K; Lin J
Anticancer Res; 2002; 22(2A):659-64. PubMed ID: 12014634
[TBL] [Abstract][Full Text] [Related]
14. Adenovirus-mediated E2F-1 gene transfer inhibits MDM2 expression and efficiently induces apoptosis in MDM2-overexpressing tumor cells.
Yang HL; Dong YB; Elliott MJ; Liu TJ; Atienza C; Stilwell A; McMasters KM
Clin Cancer Res; 1999 Aug; 5(8):2242-50. PubMed ID: 10473112
[TBL] [Abstract][Full Text] [Related]
15. Adenovirus-mediated transfer of wild-type p53 gene sensitizes TNF resistant MCF7 derivatives to the cytotoxic effect of this cytokine: relationship with c-myc and Rb.
Ameyar M; Shatrov V; Bouquet C; Capoulade C; Cai Z; Stancou R; Badie C; Haddada H; Chouaib S
Oncogene; 1999 Sep; 18(39):5464-72. PubMed ID: 10498900
[TBL] [Abstract][Full Text] [Related]
16. Growth arrest of immortalized human keratinocytes and suppression of telomerase activity by p21WAF1 gene expression.
Kallassy M; Martel N; Damour O; Yamasaki H; Nakazawa H
Mol Carcinog; 1998 Jan; 21(1):26-36. PubMed ID: 9473769
[TBL] [Abstract][Full Text] [Related]
17. Abrogation of wild-type p53 mediated growth-inhibition by nuclear exclusion.
Knippschild U; Oren M; Deppert W
Oncogene; 1996 Apr; 12(8):1755-65. PubMed ID: 8622896
[TBL] [Abstract][Full Text] [Related]
18. Cell type-specific inhibition of p53-mediated apoptosis by mdm2.
Haupt Y; Barak Y; Oren M
EMBO J; 1996 Apr; 15(7):1596-606. PubMed ID: 8612583
[TBL] [Abstract][Full Text] [Related]
19. Wild-type p53 can inhibit oncogene-mediated focus formation.
Eliyahu D; Michalovitz D; Eliyahu S; Pinhasi-Kimhi O; Oren M
Proc Natl Acad Sci U S A; 1989 Nov; 86(22):8763-7. PubMed ID: 2530586
[TBL] [Abstract][Full Text] [Related]
20. Regulation of cellular response to oncogenic and oxidative stress by Seladin-1.
Wu C; Miloslavskaya I; Demontis S; Maestro R; Galaktionov K
Nature; 2004 Dec; 432(7017):640-5. PubMed ID: 15577914
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
