These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

194 related articles for article (PubMed ID: 11063621)

  • 1. Synthesis, biological evaluation, and conformational analysis of A-ring diastereomers of 2-methyl-1,25-dihydroxyvitamin D(3) and their 20-epimers: unique activity profiles depending on the stereochemistry of the A-ring and at C-20.
    Konno K; Fujishima T; Maki S; Liu Z; Miura D; Chokki M; Ishizuka S; Yamaguchi K; Kan Y; Kurihara M; Miyata N; Smith C; DeLuca HF; Takayama H
    J Med Chem; 2000 Nov; 43(22):4247-65. PubMed ID: 11063621
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Systematic studies on synthesis, structural elucidation, and biological evaluation of A-ring diastereomers of 2-methyl-1alpha,25-dihydroxyvitamin D(3) and 20-epi-2-methyl-1alpha,25-dihydroxyvitamin D(3).
    Takayama H; Konno K; Fujishima T; Maki S; Liu Z; Miura D; Chokki M; Ishizuka S; Smith C; DeLuca HF; Nakagawa K; Kurobe M; Okano T
    Steroids; 2001; 66(3-5):277-85. PubMed ID: 11179735
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Novel ring A stereoisomers of 2-methyl-1alpha,25-dihydroxyvitamin D(3) and 2-methyl-20-epi-1alpha,25-dihydroxyvitamin D(3): transactivation of target genes and modulation of differentiation in human promyelocytic leukemia (HL-60) cells.
    Nakagawa K; Kurobe M; Ozono K; Konno K; Fujishima T; Takayama H; Okano T
    Biochem Pharmacol; 2000 Mar; 59(6):691-702. PubMed ID: 10677586
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Design, synthesis, and biological studies of the A-ring-modified 1,25-dihydroxyvitamin D3 analogs.
    Takayama H; Kittaka A; Fujishima T; Suhara Y
    Recent Results Cancer Res; 2003; 164():289-317. PubMed ID: 12899530
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Highly potent cell differentiation-inducing analogues of 1alpha,25-dihydroxyvitamin D3: synthesis and biological activity of 2-methyl-1,25-dihydroxyvitamin D3 with side-chain modifications.
    Fujishima T; Zhaopeng L; Konno K; Nakagawa K; Okano T; Yamaguchi K; Takayama H
    Bioorg Med Chem; 2001 Feb; 9(2):525-35. PubMed ID: 11249144
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Synthesis and biological activity of 2-methyl-20-epi analogues of 1 alpha,25-dihydroxyvitamin D3.
    Fujishima T; Liu Z; Miura D; Chokki M; Ishizuka S; Konno K; Takayama H
    Bioorg Med Chem Lett; 1998 Aug; 8(16):2145-8. PubMed ID: 9873502
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Synthesis and biological evaluation of all A-ring stereoisomers of 5,6-trans-2-methyl-1,25-dihydroxyvitamin D(3) and their 20-epimers: possible binding modes of potent A-ring analogues to vitamin D receptor.
    Fujishima T; Konno K; Nakagawa K; Tanaka M; Okano T; Kurihara M; Miyata N; Takayama H
    Chem Biol; 2001 Nov; 8(11):1011-24. PubMed ID: 11731293
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A novel and practical route to A-ring enyne synthon for 1 alpha,25-dihydroxyvitamin D3 analogs: synthesis of A-ring diastereomers of 1 alpha,25-dihydroxyvitamin D2 and 3-methyl-1,25-dihydroxyvitamin D3.
    Konno K; Maki S; Fujishima T; Liu Z; Miura D; Chokki M; Takayama H
    Bioorg Med Chem Lett; 1998 Jan; 8(2):151-6. PubMed ID: 9871644
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Analogs of 1alpha,25-dihydroxyvitamin D3 with high potency in induction of osteoclastogenesis and prevention of dendritic cell differentiation: synthesis and biological evaluation of 2-substituted 19-norvitamin D analogs.
    Shimazaki M; Miyamoto Y; Yamamoto K; Yamada S; Takami M; Shinki T; Udagawa N; Shimizu M
    Bioorg Med Chem; 2006 Jul; 14(13):4645-56. PubMed ID: 16513359
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Efficient synthesis and biological evaluation of all A-ring diastereomers of 1alpha,25-dihydroxyvitamin D3 and its 20-epimer.
    Fujishima T; Konno K; Nakagawa K; Kurobe M; Okano T; Takayama H
    Bioorg Med Chem; 2000 Jan; 8(1):123-34. PubMed ID: 10968271
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The antagonism between 2-methyl-1,25-dihydroxyvitamin D3 and 2-methyl-20-epi-1,25-dihydroxyvitamin D3 in non-genomic pathway-mediated biological responses induced by 1alpha,25-dihydroxyvitamin D3 assessed by NB4 cell differentiation.
    Miura D; Norman AW; Mizwicki MT; Fujishima T; Konno K; Kittaka A; Takayama H; Ishizuka S
    J Steroid Biochem Mol Biol; 2005 Apr; 94(5):469-79. PubMed ID: 15876412
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Design and efficient synthesis of 2 alpha-(omega-hydroxyalkoxy)-1 alpha,25-dihydroxyvitamin D3 Analogues, including 2-epi-ED-71 and their 20-epimers with HL-60 cell differentiation activity.
    Saito N; Suhara Y; Kurihara M; Fujishima T; Honzawa S; Takayanagi H; Kozono T; Matsumoto M; Ohmori M; Miyata N; Takayama H; Kittaka A
    J Org Chem; 2004 Oct; 69(22):7463-71. PubMed ID: 15497970
    [TBL] [Abstract][Full Text] [Related]  

  • 13. New 1alpha,25-dihydroxy-19-norvitamin D3 compounds of high biological activity: synthesis and biological evaluation of 2-hydroxymethyl, 2-methyl, and 2-methylene analogues.
    Sicinski RR; Prahl JM; Smith CM; DeLuca HF
    J Med Chem; 1998 Nov; 41(23):4662-74. PubMed ID: 9804706
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Design and synthesis of potent vitamin D receptor antagonists with A-ring modifications: remarkable effects of 2alpha-methyl introduction on antagonistic activity.
    Fujishima T; Kojima Y; Azumaya I; Kittaka A; Takayama H
    Bioorg Med Chem; 2003 Aug; 11(17):3621-31. PubMed ID: 12901907
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Fluorinated vitamin D analogs to probe the conformation of vitamin D in its receptor complex: 19F-NMR studies and biological activity.
    Ohno A; Shimizu M; Yamada S
    Chem Pharm Bull (Tokyo); 2002 Apr; 50(4):475-83. PubMed ID: 11963993
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Efficient synthesis of 2-modified 1alpha,25-dihydroxy-19-norvitamin D3 with Julia olefination: high potency in induction of differentiation on HL-60 cells.
    Ono K; Yoshida A; Saito N; Fujishima T; Honzawa S; Suhara Y; Kishimoto S; Sugiura T; Waku K; Takayama H; Kittaka A
    J Org Chem; 2003 Sep; 68(19):7407-15. PubMed ID: 12968893
    [TBL] [Abstract][Full Text] [Related]  

  • 17. New highly calcemic 1 alpha,25-dihydroxy-19-norvitamin D(3) compounds with modified side chain: 26,27-dihomo- and 26,27-dimethylene analogs in 20S-series.
    Sicinski RR; Prahl JM; Smith CM; DeLuca HF
    Steroids; 2002 Mar; 67(3-4):247-56. PubMed ID: 11856548
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Synthesis and biological activity of 2-(3'-hydroxypropylidene)-1α-hydroxy-19-norvitamin D analogues with shortened alkyl side chains.
    Glebocka A; Sicinski RR; Plum LA; Deluca HF
    J Med Chem; 2011 Oct; 54(19):6832-42. PubMed ID: 21902235
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Synthesis and biological activities of 14-epi-MART-10 and 14-epi-MART-11: implications for cancer and osteoporosis treatment.
    Kittaka A; Hara H; Takano M; Sawada D; Arai MA; Takagi K; Chida T; Harada Y; Saito H; Takenouchi K; Ishizuka S; Hayashi K; Ikushiro S; Sakaki T; Sugiura T; Chen TC
    Anticancer Res; 2009 Sep; 29(9):3563-9. PubMed ID: 19667149
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Rational design, synthesis, and biological activity of novel conformationally restricted vitamin D analogues, (22R)- and (22S)-22-ethyl-1,25-dihydroxy-23,24-didehydro-24a,24b-dihomo-20-epivitamin D(3).
    Masuno H; Yamamoto K; Wang X; Choi M; Ooizumi H; Shinki T; Yamada S
    J Med Chem; 2002 Apr; 45(9):1825-34. PubMed ID: 11960494
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.