144 related articles for article (PubMed ID: 11080626)
1. Catalytic center assembly of HPPK as revealed by the crystal structure of a ternary complex at 1.25 A resolution.
Blaszczyk J; Shi G; Yan H; Ji X
Structure; 2000 Oct; 8(10):1049-58. PubMed ID: 11080626
[TBL] [Abstract][Full Text] [Related]
2. Structure and dynamics of 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase.
Yan H; Blaszczyk J; Xiao B; Shi G; Ji X
J Mol Graph Model; 2001; 19(1):70-7. PubMed ID: 11381532
[TBL] [Abstract][Full Text] [Related]
3. Mechanism of the conformational transitions in 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase as revealed by NMR spectroscopy.
Li G; Felczak K; Shi G; Yan H
Biochemistry; 2006 Oct; 45(41):12573-81. PubMed ID: 17029412
[TBL] [Abstract][Full Text] [Related]
4. Crystal structure of 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, a potential target for the development of novel antimicrobial agents.
Xiao B; Shi G; Chen X; Yan H; Ji X
Structure; 1999 May; 7(5):489-96. PubMed ID: 10378268
[TBL] [Abstract][Full Text] [Related]
5. Dynamics of the conformational transitions in the assembling of the Michaelis complex of a bisubstrate enzyme: a (15)N relaxation study of Escherichia coli 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase.
Lescop E; Lu Z; Liu Q; Xu H; Li G; Xia B; Yan H; Jin C
Biochemistry; 2009 Jan; 48(2):302-12. PubMed ID: 19108643
[TBL] [Abstract][Full Text] [Related]
6. Reaction trajectory of pyrophosphoryl transfer catalyzed by 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase.
Blaszczyk J; Shi G; Li Y; Yan H; Ji X
Structure; 2004 Mar; 12(3):467-75. PubMed ID: 15016362
[TBL] [Abstract][Full Text] [Related]
7. An enhanced molecular dynamics study of HPPK-ATP conformation space exploration and ATP binding to HPPK.
Su L; Cukier RI
J Phys Chem A; 2009 Mar; 113(10):2025-35. PubMed ID: 19191740
[TBL] [Abstract][Full Text] [Related]
8. Structure and activity of Yersinia pestis 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase as a novel target for the development of antiplague therapeutics.
Blaszczyk J; Li Y; Cherry S; Alexandratos J; Wu Y; Shaw G; Tropea JE; Waugh DS; Yan H; Ji X
Acta Crystallogr D Biol Crystallogr; 2007 Nov; 63(Pt 11):1169-77. PubMed ID: 18007032
[TBL] [Abstract][Full Text] [Related]
9. Bisubstrate inhibitors of 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase: Transition state analogs for high affinity binding.
Shi G; Shaw GX; Zhu F; Tarasov SG; Ji X
Bioorg Med Chem; 2021 Jan; 29():115847. PubMed ID: 33199204
[TBL] [Abstract][Full Text] [Related]
10. Bisubstrate analogue inhibitors of 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase: synthesis and biochemical and crystallographic studies.
Shi G; Blaszczyk J; Ji X; Yan H
J Med Chem; 2001 Apr; 44(9):1364-71. PubMed ID: 11311059
[TBL] [Abstract][Full Text] [Related]
11. Hamiltonian replica exchange method study of Escherichia coli and Yersinia pestis HPPK.
Su L; Cukier RI
J Phys Chem B; 2009 Dec; 113(50):16197-208. PubMed ID: 19924845
[TBL] [Abstract][Full Text] [Related]
12. A Network of Conformational Transitions Revealed by Molecular Dynamics Simulations of the Binary Complex of Escherichia coli 6-Hydroxymethyl-7,8-dihydropterin Pyrophosphokinase with MgATP.
Gao K; Jia Y; Yang M
Biochemistry; 2016 Dec; 55(49):6931-6939. PubMed ID: 27951655
[TBL] [Abstract][Full Text] [Related]
13. Equilibrium and kinetic studies of substrate binding to 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase from Escherichia coli.
Bermingham A; Bottomley JR; Primrose WU; Derrick JP
J Biol Chem; 2000 Jun; 275(24):17962-7. PubMed ID: 10751386
[TBL] [Abstract][Full Text] [Related]
14. Kinetic and structural characterization of a product complex of 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase from Escherichia coli.
Garçon A; Bermingham A; Lian LY; Derrick JP
Biochem J; 2004 Jun; 380(Pt 3):867-73. PubMed ID: 15018613
[TBL] [Abstract][Full Text] [Related]
15. Bisubstrate analog inhibitors of 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase: new lead exhibits a distinct binding mode.
Shi G; Shaw G; Li Y; Wu Y; Yan H; Ji X
Bioorg Med Chem; 2012 Jul; 20(14):4303-9. PubMed ID: 22727779
[TBL] [Abstract][Full Text] [Related]
16. Structure-based design and development of functionalized Mercaptoguanine derivatives as inhibitors of the folate biosynthesis pathway enzyme 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase from Staphylococcus aureus.
Dennis ML; Chhabra S; Wang ZC; Debono A; Dolezal O; Newman J; Pitcher NP; Rahmani R; Cleary B; Barlow N; Hattarki M; Graham B; Peat TS; Baell JB; Swarbrick JD
J Med Chem; 2014 Nov; 57(22):9612-26. PubMed ID: 25357262
[TBL] [Abstract][Full Text] [Related]
17. Dynamic roles of arginine residues 82 and 92 of Escherichia coli 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase: crystallographic studies.
Blaszczyk J; Li Y; Shi G; Yan H; Ji X
Biochemistry; 2003 Feb; 42(6):1573-80. PubMed ID: 12578370
[TBL] [Abstract][Full Text] [Related]
18. The structure and mechanism of 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase.
Derrick JP
Vitam Horm; 2008; 79():411-33. PubMed ID: 18804704
[TBL] [Abstract][Full Text] [Related]
19. Bisubstrate analogue inhibitors of 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase: New design with improved properties.
Shi G; Shaw G; Liang YH; Subburaman P; Li Y; Wu Y; Yan H; Ji X
Bioorg Med Chem; 2012 Jan; 20(1):47-57. PubMed ID: 22169600
[TBL] [Abstract][Full Text] [Related]
20. Essential roles of a dynamic loop in the catalysis of 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase.
Blaszczyk J; Li Y; Wu Y; Shi G; Ji X; Yan H
Biochemistry; 2004 Feb; 43(6):1469-77. PubMed ID: 14769023
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]