397 related articles for article (PubMed ID: 11092986)
1. UCN-01 (7-hydroxystaurosporine) enhances 5-fluorouracil cytotoxicity through down-regulation of thymidylate synthetase messenger RNA.
Abe S; Kubota T; Otani Y; Furukawa T; Watanabe M; Kumai K; Kitajima M
Jpn J Cancer Res; 2000 Nov; 91(11):1192-8. PubMed ID: 11092986
[TBL] [Abstract][Full Text] [Related]
2. UCN-01 suppresses thymidylate synthase gene expression and enhances 5-fluorouracil-induced apoptosis in a sequence-dependent manner.
Hsueh CT; Kelsen D; Schwartz GK
Clin Cancer Res; 1998 Sep; 4(9):2201-6. PubMed ID: 9748140
[TBL] [Abstract][Full Text] [Related]
3. Down-regulation of thymidylate synthase expression and its steady-state mRNA by oxaliplatin in colon cancer cells.
Yeh KH; Cheng AL; Wan JP; Lin CS; Liu CC
Anticancer Drugs; 2004 Apr; 15(4):371-6. PubMed ID: 15057142
[TBL] [Abstract][Full Text] [Related]
4. Histone deacetylase inhibitor enhances 5-fluorouracil cytotoxicity by down-regulating thymidylate synthase in human cancer cells.
Lee JH; Park JH; Jung Y; Kim JH; Jong HS; Kim TY; Bang YJ
Mol Cancer Ther; 2006 Dec; 5(12):3085-95. PubMed ID: 17172411
[TBL] [Abstract][Full Text] [Related]
5. Histone deacetylase inhibitor enhances sensitivity of non-small-cell lung cancer cells to 5-FU/S-1 via down-regulation of thymidylate synthase expression and up-regulation of p21(waf1/cip1) expression.
Noro R; Miyanaga A; Minegishi Y; Okano T; Seike M; Soeno C; Kataoka K; Matsuda K; Yoshimura A; Gemma A
Cancer Sci; 2010 Jun; 101(6):1424-30. PubMed ID: 20384633
[TBL] [Abstract][Full Text] [Related]
6. Thymidylate synthetase (TS) genotype and TS/dihydropyrimidine dehydrogenase mRNA level as an indicator in determining chemosensitivity to 5-fluorouracil in advanced gastric carcinoma.
Toriumi F; Kubota T; Saikawa Y; Yoshida M; Otani Y; Watanabe M; Kumai K; Kitajima M
Anticancer Res; 2004; 24(4):2455-63. PubMed ID: 15330198
[TBL] [Abstract][Full Text] [Related]
7. CDK inhibitor enhances the sensitivity to 5-fluorouracil in colorectal cancer cells.
Takagi K; Sowa Y; Cevik OM; Nakanishi R; Sakai T
Int J Oncol; 2008 May; 32(5):1105-10. PubMed ID: 18425338
[TBL] [Abstract][Full Text] [Related]
8. Prolonged and enhanced suppression of thymidylate synthase by weekly 24-h infusion of high-dose 5-fluorouracil.
Yeh KH; Yeh SH; Hsu CH; Wang TM; Ma IF; Cheng AL
Br J Cancer; 2000 Dec; 83(11):1510-5. PubMed ID: 11076661
[TBL] [Abstract][Full Text] [Related]
9. Synergistic efficacy of 3n-butyrate and 5-fluorouracil in human colorectal cancer xenografts via modulation of DNA synthesis.
Bras-Gonçalves RA; Pocard M; Formento JL; Poirson-Bichat F; De Pinieux G; Pandrea I; Arvelo F; Ronco G; Villa P; Coquelle A; Milano G; Lesuffleur T; Dutrillaux B; Poupon MF
Gastroenterology; 2001 Mar; 120(4):874-88. PubMed ID: 11231942
[TBL] [Abstract][Full Text] [Related]
10. Arsenic trioxide suppresses thymidylate synthase in 5-FU-resistant colorectal cancer cell line HT29 In Vitro re-sensitizing cells to 5-FU.
Subbarayan PR; Lee K; Ardalan B
Anticancer Res; 2010 Apr; 30(4):1157-62. PubMed ID: 20530422
[TBL] [Abstract][Full Text] [Related]
11. Influence of p53 status on radiation and 5-flourouracil synergy in pancreatic cancer cells.
Mohiuddin M; Chendil D; Dey S; Alcock RA; Regine W; Mohiuddin M; Ahmed MM
Anticancer Res; 2002; 22(2A):825-30. PubMed ID: 12014658
[TBL] [Abstract][Full Text] [Related]
12. Phase I trial of the cyclin-dependent kinase inhibitor and protein kinase C inhibitor 7-hydroxystaurosporine in combination with Fluorouracil in patients with advanced solid tumors.
Kortmansky J; Shah MA; Kaubisch A; Weyerbacher A; Yi S; Tong W; Sowers R; Gonen M; O'reilly E; Kemeny N; Ilson DI; Saltz LB; Maki RG; Kelsen DP; Schwartz GK
J Clin Oncol; 2005 Mar; 23(9):1875-84. PubMed ID: 15699481
[TBL] [Abstract][Full Text] [Related]
13. Combined therapy with a thymidylate synthase-inhibiting vector and S-1 has effective antitumor activity against 5-FU-resistant tumors.
Kadota K; Huang CL; Liu D; Yokomise H; Haba R; Wada H
Int J Oncol; 2011 Feb; 38(2):355-63. PubMed ID: 21174056
[TBL] [Abstract][Full Text] [Related]
14. Gossypol sensitizes the antitumor activity of 5-FU through down-regulation of thymidylate synthase in human colon carcinoma cells.
Yang D; Qu J; Qu X; Cao Y; Xu L; Hou K; Feng W; Liu Y
Cancer Chemother Pharmacol; 2015 Sep; 76(3):575-86. PubMed ID: 26208739
[TBL] [Abstract][Full Text] [Related]
15. Different pathways of 5-fluorouracil metabolism after continuous venous or bolus injection in patients with colon carcinoma: possible predictive value of thymidylate synthetase mRNA and ribonucleotide reductase for 5-fluorouracil sensitivity.
Kubota T; Watanabe M; Otani Y; Kitajima M; Fukushiuma M
Anticancer Res; 2002; 22(6B):3537-40. PubMed ID: 12552952
[TBL] [Abstract][Full Text] [Related]
16. Biochemical and molecular effects of UCN-01 in combination with 5-fluorodeoxyuridine in A431 human epidermoid cancer cells.
Grem JL; Danenberg KD; Kao V; Danenberg PV; Nguyen D
Anticancer Drugs; 2002 Mar; 13(3):259-70. PubMed ID: 11984070
[TBL] [Abstract][Full Text] [Related]
17. Combinations of 5-fluorouracil with UCN-01 or staurosporine.
Sigmond J; Comijn EM; Kamphuis JA; Peters GJ
Nucleosides Nucleotides Nucleic Acids; 2004 Oct; 23(8-9):1503-6. PubMed ID: 15571286
[TBL] [Abstract][Full Text] [Related]
18. Induction of thymidylate synthase as a 5-fluorouracil resistance mechanism.
Peters GJ; Backus HH; Freemantle S; van Triest B; Codacci-Pisanelli G; van der Wilt CL; Smid K; Lunec J; Calvert AH; Marsh S; McLeod HL; Bloemena E; Meijer S; Jansen G; van Groeningen CJ; Pinedo HM
Biochim Biophys Acta; 2002 Jul; 1587(2-3):194-205. PubMed ID: 12084461
[TBL] [Abstract][Full Text] [Related]
19. Interferon beta increases antitumor activity of 5-fluorouracil against human colon carcinoma cells in vitro and in vivo.
Kase S; Kubota T; Watanabe M; Furukawa T; Tanino H; Ishibiki K; Teramoto T; Kitajima M
Anticancer Res; 1993; 13(2):369-73. PubMed ID: 8517649
[TBL] [Abstract][Full Text] [Related]
20. Synergistic antitumor effect of combined 5-fluorouracil (5-FU) with 5-chloro-2,4-dihydroxypyridine on 5-FU-resistant gastric cancer cells: possible role of a dihydropyrimidine dehydrogenase-independent mechanism.
Sasaki E; Tominaga K; Kuwamura H; Watanabe T; Fujiwara Y; Oshitani N; Higuchi K; Arakawa T
J Gastroenterol; 2007 Oct; 42(10):816-22. PubMed ID: 17940834
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]