99 related articles for article (PubMed ID: 11095573)
1. Increased absorption of the antiviral ester prodrug tenofovir disoproxil in rat ileum by inhibiting its intestinal metabolism.
Van Gelder J; Deferme S; Annaert P; Naesens L; De Clercq E; Van den Mooter G; Kinget R; Augustijns P
Drug Metab Dispos; 2000 Dec; 28(12):1394-6. PubMed ID: 11095573
[TBL] [Abstract][Full Text] [Related]
2. Intestinal absorption enhancement of the ester prodrug tenofovir disoproxil fumarate through modulation of the biochemical barrier by defined ester mixtures.
van Gelder J; Deferme S; Naesens L; De Clercq E; van den Mooter G; Kinget R; Augustijns P
Drug Metab Dispos; 2002 Aug; 30(8):924-30. PubMed ID: 12124311
[TBL] [Abstract][Full Text] [Related]
3. Inhibition of intestinal metabolism of the antiviral ester prodrug bis(POC)-PMPA by nature-identical fruit extracts as a strategy to enhance its oral absorption: an in vitro study.
Van Gelder J; Annaert P; Naesens L; De Clercq E; Van den Mooter G; Kinget R; Augustijns P
Pharm Res; 1999 Jul; 16(7):1035-40. PubMed ID: 10450927
[TBL] [Abstract][Full Text] [Related]
4. Effects of human immunodeficiency virus protease inhibitors on the intestinal absorption of tenofovir disoproxil fumarate in vitro.
Tong L; Phan TK; Robinson KL; Babusis D; Strab R; Bhoopathy S; Hidalgo IJ; Rhodes GR; Ray AS
Antimicrob Agents Chemother; 2007 Oct; 51(10):3498-504. PubMed ID: 17664327
[TBL] [Abstract][Full Text] [Related]
5. Species-dependent and site-specific intestinal metabolism of ester prodrugs.
Van Gelder J; Shafiee M; De Clercq E; Penninckx F; Van den Mooter G; Kinget R; Augustijns P
Int J Pharm; 2000 Sep; 205(1-2):93-100. PubMed ID: 11000545
[TBL] [Abstract][Full Text] [Related]
6. In vitro and in vivo evaluations of intestinal barriers for the zwitterion L-767,679 and its carboxyl ester prodrug L-775,318. Roles of efflux and metabolism.
Prueksaritanont T; DeLuna P; Gorham LM; Ma B; Cohn D; Pang J; Xu X; Leung K; Lin JH
Drug Metab Dispos; 1998 Jun; 26(6):520-7. PubMed ID: 9616186
[TBL] [Abstract][Full Text] [Related]
7. In vitro, ex vivo, and in situ intestinal absorption characteristics of the antiviral ester prodrug adefovir dipivoxil.
Annaert P; Tukker JJ; van Gelder J; Naesens L; de Clercq E; van Den Mooter G; Kinget R; Augustijns P
J Pharm Sci; 2000 Aug; 89(8):1054-62. PubMed ID: 10906729
[TBL] [Abstract][Full Text] [Related]
8. A study of the intestinal absorption of an ester-type prodrug, ME3229, in rats: active efflux transport as a cause of poor bioavailability of the active drug.
Okudaira N; Tatebayashi T; Speirs GC; Komiya I; Sugiyama Y
J Pharmacol Exp Ther; 2000 Aug; 294(2):580-7. PubMed ID: 10900235
[TBL] [Abstract][Full Text] [Related]
9. Transport, uptake, and metabolism of the bis(pivaloyloxymethyl)-ester prodrug of 9-(2-phosphonylmethoxyethyl)adenine in an in vitro cell culture system of the intestinal mucosa (Caco-2).
Annaert P; Kinget R; Naesens L; de Clercq E; Augustijns P
Pharm Res; 1997 Apr; 14(4):492-6. PubMed ID: 9144737
[TBL] [Abstract][Full Text] [Related]
10. Intestinal absorption of hawthorn flavonoids--in vitro, in situ and in vivo correlations.
Zuo Z; Zhang L; Zhou L; Chang Q; Chow M
Life Sci; 2006 Nov; 79(26):2455-62. PubMed ID: 16989871
[TBL] [Abstract][Full Text] [Related]
11. Pharmacokinetic study of tenofovir disoproxil fumarate combined with rifampin in healthy volunteers.
Droste JA; Verweij-van Wissen CP; Kearney BP; Buffels R; Vanhorssen PJ; Hekster YA; Burger DM
Antimicrob Agents Chemother; 2005 Feb; 49(2):680-4. PubMed ID: 15673751
[TBL] [Abstract][Full Text] [Related]
12. Intestinal behavior of the ester prodrug tenofovir DF in humans.
Geboers S; Haenen S; Mols R; Brouwers J; Tack J; Annaert P; Augustijns P
Int J Pharm; 2015 May; 485(1-2):131-7. PubMed ID: 25747454
[TBL] [Abstract][Full Text] [Related]
13. Absence of clinically relevant pharmacokinetic interaction between ribavirin and tenofovir in healthy subjects.
Ramanathan S; Cheng A; Mittan A; Ebrahimi R; Kearney BP
J Clin Pharmacol; 2006 May; 46(5):559-66. PubMed ID: 16638739
[TBL] [Abstract][Full Text] [Related]
14. Absorption and intestinal metabolism of purine dideoxynucleosides and an adenosine deaminase-activated prodrug of 2',3'-dideoxyinosine in the mesenteric vein cannulated rat ileum.
Singhal D; Ho NF; Anderson BD
J Pharm Sci; 1998 May; 87(5):569-77. PubMed ID: 9572907
[TBL] [Abstract][Full Text] [Related]
15. Development of a Novel Formulation That Improves Preclinical Bioavailability of Tenofovir Disoproxil Fumarate.
Watkins ME; Wring S; Randolph R; Park S; Powell K; Lutz L; Nowakowski M; Ramabhadran R; Domanico PL
J Pharm Sci; 2017 Mar; 106(3):906-919. PubMed ID: 27986599
[TBL] [Abstract][Full Text] [Related]
16. In vitro behavior of a phosphate ester prodrug of amprenavir in human intestinal fluids and in the Caco-2 system: illustration of intraluminal supersaturation.
Brouwers J; Tack J; Augustijns P
Int J Pharm; 2007 May; 336(2):302-9. PubMed ID: 17207947
[TBL] [Abstract][Full Text] [Related]
17. Drug-drug and drug-food interactions between tenofovir disoproxil fumarate and didanosine.
Kearney BP; Sayre JR; Flaherty JF; Chen SS; Kaul S; Cheng AK
J Clin Pharmacol; 2005 Dec; 45(12):1360-7. PubMed ID: 16291710
[TBL] [Abstract][Full Text] [Related]
18. Sulfasalazine transport in in-vitro, ex-vivo and in-vivo absorption models: contribution of efflux carriers and their modulation by co-administration of synthetic nature-identical fruit extracts.
Mols R; Deferme S; Augustijns P
J Pharm Pharmacol; 2005 Dec; 57(12):1565-73. PubMed ID: 16354400
[TBL] [Abstract][Full Text] [Related]
19. Evaluation of the potential of ion pair formation to improve the oral absorption of two potent antiviral compounds, AMD3100 and PMPA.
Van Gelder J; Witvrouw M; Pannecouque C; Henson G; Bridger G; Naesens L; De Clercq E; Annaert P; Shafiee M; Van den Mooter G; Kinget R; Augustijns P
Int J Pharm; 1999 Sep; 186(2):127-36. PubMed ID: 10486430
[TBL] [Abstract][Full Text] [Related]
20. Optimization of the local inhibition of intestinal adenosine deaminase (ADA) by erythro-9-(2-hydroxy-3-nonyl)adenine: enhanced oral delivery of an ADA-activated prodrug for anti-HIV therapy.
Singhal D; Anderson BD
J Pharm Sci; 1998 May; 87(5):578-85. PubMed ID: 9572908
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
