These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

407 related articles for article (PubMed ID: 11095582)

  • 1. Identification of the human liver cytochrome P450 isoenzyme responsible for the 6-methylhydroxylation of the novel anticancer drug 5,6-dimethylxanthenone-4-acetic acid.
    Zhou S; Paxton JW; Tingle MD; Kestell P
    Drug Metab Dispos; 2000 Dec; 28(12):1449-56. PubMed ID: 11095582
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Gender differences in the metabolism and pharmacokinetics of the experimental anticancer agent 5,6-dimethylxanthenone-4-acetic acid (DMXAA).
    Zhou S; Kestell P; Tingle MD; Paxton JW
    Cancer Chemother Pharmacol; 2002 Feb; 49(2):126-32. PubMed ID: 11862426
    [TBL] [Abstract][Full Text] [Related]  

  • 3. [O-methyl 14C]naproxen O-demethylase activity in human liver microsomes: evidence for the involvement of cytochrome P4501A2 and P4502C9/10.
    Rodrigues AD; Kukulka MJ; Roberts EM; Ouellet D; Rodgers TR
    Drug Metab Dispos; 1996 Jan; 24(1):126-36. PubMed ID: 8825200
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Identification of human cytochrome P450 isoforms involved in the 3-hydroxylation of quinine by human live microsomes and nine recombinant human cytochromes P450.
    Zhao XJ; Yokoyama H; Chiba K; Wanwimolruk S; Ishizaki T
    J Pharmacol Exp Ther; 1996 Dec; 279(3):1327-34. PubMed ID: 8968357
    [TBL] [Abstract][Full Text] [Related]  

  • 5. 6-methylhydroxylation of the anti-cancer agent 5,6-dimethylxanthenone-4-acetic acid (DMXAA) by flavin-containing monooxygenase 3.
    Zhou S; Kestell P; Paxton JW
    Eur J Drug Metab Pharmacokinet; 2002; 27(3):179-83. PubMed ID: 12365199
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Cytochrome P450 inhibitors. Evaluation of specificities in the in vitrometabolism of therapeutic agents by human liver microsomes.
    Newton DJ; Wang RW; Lu AY
    Drug Metab Dispos; 1995 Jan; 23(1):154-8. PubMed ID: 7720520
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Interaction of cisapride with the human cytochrome P450 system: metabolism and inhibition studies.
    Desta Z; Soukhova N; Mahal SK; Flockhart DA
    Drug Metab Dispos; 2000 Jul; 28(7):789-800. PubMed ID: 10859153
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Effects of freezing, thawing, and storing human liver microsomes on cytochrome P450 activity.
    Pearce RE; McIntyre CJ; Madan A; Sanzgiri U; Draper AJ; Bullock PL; Cook DC; Burton LA; Latham J; Nevins C; Parkinson A
    Arch Biochem Biophys; 1996 Jul; 331(2):145-69. PubMed ID: 8660694
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Identification of the human liver cytochrome P450 isoenzymes responsible for the 5-methylhydroxylation of the novel anti-fibrotic drug AKF-PD.
    He X; Luo X; Liu Z; Hu G; Cheng Z
    Xenobiotica; 2011 Oct; 41(10):844-50. PubMed ID: 21679010
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Potent inhibition of the cytochrome P-450 3A-mediated human liver microsomal metabolism of a novel HIV protease inhibitor by ritonavir: A positive drug-drug interaction.
    Kumar GN; Dykstra J; Roberts EM; Jayanti VK; Hickman D; Uchic J; Yao Y; Surber B; Thomas S; Granneman GR
    Drug Metab Dispos; 1999 Aug; 27(8):902-8. PubMed ID: 10421617
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Strain differences in the liver microsomal metabolism of the experimental anti-tumour agent 5,6-dimethylxanthenone-4-acetic acid in mice.
    Zhou S; Kestell P; Paxton JW
    J Chromatogr B Analyt Technol Biomed Life Sci; 2002 Sep; 776(2):231-6. PubMed ID: 12138005
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Effects of anticancer drugs on the metabolism of the anticancer drug 5,6-dimethylxanthenone-4-acetic (DMXAA) by human liver microsomes.
    Zhou S; Chin R; Kestell P; Tingle MD; Paxton JW
    Br J Clin Pharmacol; 2001 Aug; 52(2):129-36. PubMed ID: 11488768
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Preclinical factors influencing the relative contributions of Phase I and II enzymes to the metabolism of the experimental anti-cancer drug 5,6-dimethylxanthenone-4-acetic acid.
    Zhou S; Kestell P; Baguley BC; Paxton JW
    Biochem Pharmacol; 2003 Jan; 65(1):109-20. PubMed ID: 12473385
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The metabolism of the piperazine-type phenothiazine neuroleptic perazine by the human cytochrome P-450 isoenzymes.
    Wójcikowski J; Pichard-Garcia L; Maurel P; Daniel WA
    Eur Neuropsychopharmacol; 2004 May; 14(3):199-208. PubMed ID: 15056479
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Identification of the human P-450 enzymes responsible for the sulfoxidation and thiono-oxidation of diethyldithiocarbamate methyl ester: role of P-450 enzymes in disulfiram bioactivation.
    Madan A; Parkinson A; Faiman MD
    Alcohol Clin Exp Res; 1998 Sep; 22(6):1212-9. PubMed ID: 9756035
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Identification of the main human cytochrome P450 enzymes involved in safrole 1'-hydroxylation.
    Ueng YF; Hsieh CH; Don MJ; Chi CW; Ho LK
    Chem Res Toxicol; 2004 Aug; 17(8):1151-6. PubMed ID: 15310247
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Cytochrome P450 isoform inhibitors as a tool for the investigation of metabolic reactions catalyzed by human liver microsomes.
    Bourrié M; Meunier V; Berger Y; Fabre G
    J Pharmacol Exp Ther; 1996 Apr; 277(1):321-32. PubMed ID: 8613937
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Studies on the cytochrome P450 (CYP)-mediated metabolic properties of miocamycin: evaluation of the possibility of a metabolic intermediate complex formation with CYP, and identification of the human CYP isoforms.
    Kasahara M; Suzuki H; Komiya I
    Drug Metab Dispos; 2000 Apr; 28(4):409-17. PubMed ID: 10725309
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Cytochrome P4502C9 is the principal catalyst of racemic acenocoumarol hydroxylation reactions in human liver microsomes.
    Thijssen HH; Flinois JP; Beaune PH
    Drug Metab Dispos; 2000 Nov; 28(11):1284-90. PubMed ID: 11038154
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Involvement of human liver cytochrome P450 3A in vinblastine metabolism: drug interactions.
    Zhou-Pan XR; Sérée E; Zhou XJ; Placidi M; Maurel P; Barra Y; Rahmani R
    Cancer Res; 1993 Nov; 53(21):5121-6. PubMed ID: 8221648
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 21.