These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

121 related articles for article (PubMed ID: 11098130)

  • 1. Biochemical identification of the neutral endopeptidase family member responsible for the catabolism of amyloid beta peptide in the brain.
    Takaki Y; Iwata N; Tsubuki S; Taniguchi S; Toyoshima S; Lu B; Gerard NP; Gerard C; Lee HJ; Shirotani K; Saido TC
    J Biochem; 2000 Dec; 128(6):897-902. PubMed ID: 11098130
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Neprilysin degrades both amyloid beta peptides 1-40 and 1-42 most rapidly and efficiently among thiorphan- and phosphoramidon-sensitive endopeptidases.
    Shirotani K; Tsubuki S; Iwata N; Takaki Y; Harigaya W; Maruyama K; Kiryu-Seo S; Kiyama H; Iwata H; Tomita T; Iwatsubo T; Saido TC
    J Biol Chem; 2001 Jun; 276(24):21895-901. PubMed ID: 11278416
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Clearance of extracellular and cell-associated amyloid beta peptide through viral expression of neprilysin in primary neurons.
    Hama E; Shirotani K; Masumoto H; Sekine-Aizawa Y; Aizawa H; Saido TC
    J Biochem; 2001 Dec; 130(6):721-6. PubMed ID: 11726269
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Neprilysin degrades murine Amyloid-β (Aβ) more efficiently than human Aβ: Further implication for species-specific amyloid accumulation.
    Becker M; Moore A; Naughton M; Boland B; Siems WE; Walther T
    Neurosci Lett; 2018 Nov; 686():74-79. PubMed ID: 30144539
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A highly sensitive peptide substrate for detecting two Aß-degrading enzymes: neprilysin and insulin-degrading enzyme.
    Chen PT; Liao TY; Hu CJ; Wu ST; Wang SS; Chen RP
    J Neurosci Methods; 2010 Jun; 190(1):57-62. PubMed ID: 20435063
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Identification of the major Abeta1-42-degrading catabolic pathway in brain parenchyma: suppression leads to biochemical and pathological deposition.
    Iwata N; Tsubuki S; Takaki Y; Watanabe K; Sekiguchi M; Hosoki E; Kawashima-Morishima M; Lee HJ; Hama E; Sekine-Aizawa Y; Saido TC
    Nat Med; 2000 Feb; 6(2):143-50. PubMed ID: 10655101
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Human membrane metallo-endopeptidase-like protein degrades both beta-amyloid 42 and beta-amyloid 40.
    Huang JY; Bruno AM; Patel CA; Huynh AM; Philibert KD; Glucksman MJ; Marr RA
    Neuroscience; 2008 Jul; 155(1):258-62. PubMed ID: 18571334
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Understanding molecular mechanisms of proteolysis in Alzheimer's disease: progress toward therapeutic interventions.
    Higuchi M; Iwata N; Saido TC
    Biochim Biophys Acta; 2005 Aug; 1751(1):60-7. PubMed ID: 16054018
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Neprilysin and amyloid beta peptide degradation.
    Hersh LB; Rodgers DW
    Curr Alzheimer Res; 2008 Apr; 5(2):225-31. PubMed ID: 18393807
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Design of Peptide Substrate for Sensitively and Specifically Detecting Two Aβ-Degrading Enzymes: Neprilysin and Angiotensin-Converting Enzyme.
    Chen PT; Chen CL; Lin LT; Lo CH; Hu CJ; Chen RP; Wang SS
    PLoS One; 2016; 11(4):e0153360. PubMed ID: 27096746
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Amyloid beta-degrading cryptidases: insulin degrading enzyme, presequence peptidase, and neprilysin.
    Malito E; Hulse RE; Tang WJ
    Cell Mol Life Sci; 2008 Aug; 65(16):2574-85. PubMed ID: 18470479
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Proadrenomedullin N-terminal 20 peptide is rapidly cleaved by neutral endopeptidase.
    Nagatomo Y; Kitamura K; Kangawa K; Fujimoto Y; Eto T
    Biochem Biophys Res Commun; 1996 Jun; 223(3):539-43. PubMed ID: 8687431
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Reducing amyloid plaque burden via ex vivo gene delivery of an Abeta-degrading protease: a novel therapeutic approach to Alzheimer disease.
    Hemming ML; Patterson M; Reske-Nielsen C; Lin L; Isacson O; Selkoe DJ
    PLoS Med; 2007 Aug; 4(8):e262. PubMed ID: 17760499
    [TBL] [Abstract][Full Text] [Related]  

  • 14. β-Amyloid and neprilysin computational studies identify critical residues implicated in binding specificity.
    Pope D; Madura JD; Cascio M
    J Chem Inf Model; 2014 Apr; 54(4):1157-65. PubMed ID: 24650257
    [TBL] [Abstract][Full Text] [Related]  

  • 15. γ-Hydroxybutyrate (Xyrem) ameliorates clinical symptoms and neuropathology in a mouse model of Alzheimer's disease.
    Klein C; Mathis C; Leva G; Patte-Mensah C; Cassel JC; Maitre M; Mensah-Nyagan AG
    Neurobiol Aging; 2015 Feb; 36(2):832-44. PubMed ID: 25457559
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Neprilysin Is Suppressed by Dual-Specificity Tyrosine-Phosphorylation Regulated Kinase 1A (DYRK1A) in Down-Syndrome-Derived Fibroblasts.
    Kawakubo T; Mori R; Shirotani K; Iwata N; Asai M
    Biol Pharm Bull; 2017; 40(3):327-333. PubMed ID: 28250274
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Kinetics of amyloid beta-protein degradation determined by novel fluorescence- and fluorescence polarization-based assays.
    Leissring MA; Lu A; Condron MM; Teplow DB; Stein RL; Farris W; Selkoe DJ
    J Biol Chem; 2003 Sep; 278(39):37314-20. PubMed ID: 12867419
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Tat peptides inhibit neprilysin.
    Daily A; Nath A; Hersh LB
    J Neurovirol; 2006 Jun; 12(3):153-60. PubMed ID: 16877296
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Metabolic regulation of brain Abeta by neprilysin.
    Iwata N; Tsubuki S; Takaki Y; Shirotani K; Lu B; Gerard NP; Gerard C; Hama E; Lee HJ; Saido TC
    Science; 2001 May; 292(5521):1550-2. PubMed ID: 11375493
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Identification of Small Peptides in Human Cerebrospinal Fluid upon Amyloid-β Degradation.
    Mizuta N; Yanagida K; Kodama T; Tomonaga T; Takami M; Oyama H; Kudo T; Ikeda M; Takeda M; Tagami S; Okochi M
    Neurodegener Dis; 2017; 17(2-3):103-109. PubMed ID: 28103595
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.