These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

110 related articles for article (PubMed ID: 11106503)

  • 1. Mechanisms of inactivation of human S-adenosylhomocysteine hydrolase by 5',5',6',6'-tetradehydro-6'-deoxy-6'-halohomoadenosines.
    Yang X; Yin D; Wnuk SF; Robins MJ; Borchardt RT
    Biochemistry; 2000 Dec; 39(49):15234-41. PubMed ID: 11106503
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Mechanism of inactivation of S-adenosylhomocysteine hydrolase by (E)-5',6'-didehydro-6'-deoxy-6'-halohomoadenosines.
    Yuan CS; Liu S; Wnuk SF; Robins MJ; Borchardt RT
    Biochemistry; 1994 Mar; 33(12):3758-65. PubMed ID: 8142376
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A novel mechanism-based inhibitor (6'-bromo-5', 6'-didehydro-6'-deoxy-6'-fluorohomoadenosine) that covalently modifies human placental S-adenosylhomocysteine hydrolase.
    Yuan CS; Wnuk SF; Robins MJ; Borchardt RT
    J Biol Chem; 1998 Jul; 273(29):18191-7. PubMed ID: 9660780
    [TBL] [Abstract][Full Text] [Related]  

  • 4. (E)-5',6'-didehydro-6'-deoxy-6'-fluorohomoadenosine: a substrate that measures the hydrolytic activity of S-adenosylhomocysteine hydrolase.
    Yuan CS; Wnuk SF; Liu S; Robins MJ; Borchardt RT
    Biochemistry; 1994 Oct; 33(40):12305-11. PubMed ID: 7918452
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Mechanism of inactivation of S-adenosylhomocysteine hydrolase by (Z)-4',5'-didehydro-5'-deoxy-5'-fluoroadenosine.
    Yuan CS; Yeh J; Liu S; Borchardt RT
    J Biol Chem; 1993 Aug; 268(23):17030-7. PubMed ID: 8349591
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A single mutation at lysine 426 of human placental S-adenosylhomocysteine hydrolase inactivates the enzyme.
    Ault-Riché DB; Yuan CS; Borchardt RT
    J Biol Chem; 1994 Dec; 269(50):31472-8. PubMed ID: 7989313
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The effect of aliphatic adenine analogues on S-adenosylhomocysteine and S-adenosylhomocysteine hydrolase in intact rat hepatocytes.
    Schanche JS; Schanche T; Ueland PM; Holý A; Votruba I
    Mol Pharmacol; 1984 Nov; 26(3):553-8. PubMed ID: 6493210
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Comparison of the inhibition of type A and type B S-adenosylhomocysteine hydrolase: effects of cofactor content on inhibition behavior and nucleoside binding.
    Parry RJ; Muscate A; Hertel LW
    J Enzyme Inhib; 1995; 8(4):243-53. PubMed ID: 7542321
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Nucleic acid related compounds. 84. Synthesis of 6'-(E and Z)-halohomovinyl derivatives of adenosine, inactivation of S-adenosyl-L-homocysteine hydrolase, and correlation of anticancer and antiviral potencies with enzyme inhibition.
    Wnuk SF; Yuan CS; Borchardt RT; Balzarini J; De Clercq E; Robins MJ
    J Med Chem; 1994 Oct; 37(21):3579-87. PubMed ID: 7932585
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Inactivation of S-adenosyl-L-homocysteine hydrolase and antiviral activity with 5',5',6',6'-tetradehydro-6'-deoxy-6'-halohomoadenosine analogues (4'-haloacetylene analogues derived from adenosine).
    Robins MJ; Wnuk SF; Yang X; Yuan CS; Borchardt RT; Balzarini J; De Clercq E
    J Med Chem; 1998 Sep; 41(20):3857-64. PubMed ID: 9748360
    [TBL] [Abstract][Full Text] [Related]  

  • 11. S-Adenosylhomocysteinase: mechanism of inactivation by 2'-deoxyadenosine and interaction with other nucleosides.
    Abeles RH; Fish S; Lapinskas B
    Biochemistry; 1982 Oct; 21(22):5557-62. PubMed ID: 6983366
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The mechanism of inactivation of human placental S-adenosylhomocysteine hydrolase by (E)-4',5'-didehydro-5'-methoxyadenosine and adenosine 5'-carboxaldehyde oxime.
    Huang H; Yuan CS; Wnuk SF; Robins MJ; Borchardt RT
    Arch Biochem Biophys; 1997 Jul; 343(1):109-17. PubMed ID: 9210652
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Discovery of type II (covalent) inactivation of S-adenosyl-L-homocysteine hydrolase involving its "hydrolytic activity": synthesis and evaluation of dihalohomovinyl nucleoside analogues derived from adenosine.
    Wnuk SF; Mao Y; Yuan CS; Borchardt RT; Andrei G; Balzarini J; De Clercq E; Robins MJ
    J Med Chem; 1998 Jul; 41(16):3078-83. PubMed ID: 9685247
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The mechanism of inhibition of Alcaligenes faecalis S-adenosylhomocysteine hydrolase by neplanocin A.
    Matuszewska B; Borchardt RT
    Arch Biochem Biophys; 1987 Jul; 256(1):50-5. PubMed ID: 3606132
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Influence of S-adenosylhomocysteine hydrolase inhibitors on S-adenosylhomocysteine and S-adenosylmethionine pool levels in L929 cells.
    Cools M; De Clercq E
    Biochem Pharmacol; 1990 Nov; 40(10):2259-64. PubMed ID: 2244927
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Adenosine binding sites at S-adenosylhomocysteine hydrolase are controlled by the NAD+/NADH ratio of the enzyme.
    Kloor D; Lüdtke A; Stoeva S; Osswald H
    Biochem Pharmacol; 2003 Dec; 66(11):2117-23. PubMed ID: 14609736
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Determinants for the cAMP-binding site at the S-adenosylhomocysteine-hydrolase.
    Kloor D; Hermes M; Kirschler J; Müller M; Hagen N; Kalbacher H; Stevanovic S; Osswald H
    Naunyn Schmiedebergs Arch Pharmacol; 2009 Sep; 380(3):215-22. PubMed ID: 19547959
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Photoaffinity labeling of human placental S-adenosylhomocysteine hydrolase with [2-3H]8-azido-adenosine.
    Yuan CS; Borchardt RT
    J Biol Chem; 1995 Jul; 270(27):16140-6. PubMed ID: 7608178
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Ligand-dependent changes in intrinsic fluorescence of S-adenosylhomocysteine hydrolase: implications for the mechanism of inhibitor-induced inhibition.
    Yuan CS; Yeh J; Squier TC; Rawitch A; Borchardt RT
    Biochemistry; 1993 Oct; 32(39):10414-22. PubMed ID: 8399185
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The role of nicotinamide adenine dinucleotide in the inhibition of bovine liver S-adenosylhomocysteine hydrolase by neplanocin A.
    Matuszewska B; Borchardt RT
    J Biol Chem; 1987 Jan; 262(1):265-8. PubMed ID: 3025205
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.