BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

214 related articles for article (PubMed ID: 11106582)

  • 1. S20G mutant amylin exhibits increased in vitro amyloidogenicity and increased intracellular cytotoxicity compared to wild-type amylin.
    Sakagashira S; Hiddinga HJ; Tateishi K; Sanke T; Hanabusa T; Nanjo K; Eberhardt NL
    Am J Pathol; 2000 Dec; 157(6):2101-9. PubMed ID: 11106582
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The S20G substitution in hIAPP is more amyloidogenic and cytotoxic than wild-type hIAPP in mouse islets.
    Meier DT; Entrup L; Templin AT; Hogan MF; Mellati M; Zraika S; Hull RL; Kahn SE
    Diabetologia; 2016 Oct; 59(10):2166-71. PubMed ID: 27393137
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Intracellular amyloidogenesis by human islet amyloid polypeptide induces apoptosis in COS-1 cells.
    Hiddinga HJ; Eberhardt NL
    Am J Pathol; 1999 Apr; 154(4):1077-88. PubMed ID: 10233846
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Enhanced in vitro production of amyloid-like fibrils from mutant (S20G) islet amyloid polypeptide.
    Ma Z; Westermark GT; Sakagashira S; Sanke T; Gustavsson A; Sakamoto H; Engström U; Nanjo K; Westermark P
    Amyloid; 2001 Dec; 8(4):242-9. PubMed ID: 11791616
    [TBL] [Abstract][Full Text] [Related]  

  • 5. S20G mutation of the amylin gene is associated with Type II diabetes in Japanese. Study Group of Comprehensive Analysis of Genetic Factors in Diabetes Mellitus.
    Seino S;
    Diabetologia; 2001 Jul; 44(7):906-9. PubMed ID: 11508277
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Missense mutation of amylin gene (S20G) in Japanese NIDDM patients.
    Sakagashira S; Sanke T; Hanabusa T; Shimomura H; Ohagi S; Kumagaye KY; Nakajima K; Nanjo K
    Diabetes; 1996 Sep; 45(9):1279-81. PubMed ID: 8772735
    [TBL] [Abstract][Full Text] [Related]  

  • 7. [S20G mutation of amylin gene--amyloid diabetes due to S20G amylin gene mutation].
    Sanke T; Sakagashira S
    Nihon Rinsho; 2005 Feb; 63 Suppl 2():160-5. PubMed ID: 15779362
    [No Abstract]   [Full Text] [Related]  

  • 8. S20G mutation of the amylin gene is associated with a lower body mass index in Korean type 2 diabetic patients.
    Cho YM; Kim M; Park KS; Kim SY; Lee HK
    Diabetes Res Clin Pract; 2003 May; 60(2):125-9. PubMed ID: 12706321
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Molecular insights into the oligomerization dynamics and conformations of amyloidogenic and non-amyloidogenic amylin from discrete molecular dynamics simulations.
    Wang Y; Liu Y; Zhang Y; Wei G; Ding F; Sun Y
    Phys Chem Chem Phys; 2022 Sep; 24(36):21773-21785. PubMed ID: 36098068
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Fibril structures of diabetes-related amylin variants reveal a basis for surface-templated assembly.
    Gallardo R; Iadanza MG; Xu Y; Heath GR; Foster R; Radford SE; Ranson NA
    Nat Struct Mol Biol; 2020 Nov; 27(11):1048-1056. PubMed ID: 32929282
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Complete characterization of the mutation landscape reveals the effect on amylin stability and amyloidogenicity.
    Smaoui MR; Waldispühl J
    Proteins; 2015 Jun; 83(6):1014-26. PubMed ID: 25809921
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Human islet amyloid polypeptide expression in COS-1 cells. A model of intracellular amyloidogenesis.
    O'Brien TD; Butler PC; Kreutter DK; Kane LA; Eberhardt NL
    Am J Pathol; 1995 Sep; 147(3):609-16. PubMed ID: 7677175
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Expression of wild-type and mutant S20G hIAPP in physiologic knock-in mouse models fails to induce islet amyloid formation, but induces mild glucose intolerance.
    Hiddinga HJ; Sakagashira S; Ishigame M; Madde P; Sanke T; Nanjo K; Kudva YC; Lee JJ; van Deursen J; Eberhardt NL
    J Diabetes Investig; 2012 Mar; 3(2):138-47. PubMed ID: 24843557
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Analysis of Amylin Consensus Sequences Suggests That Human Amylin Is Not Optimized to Minimize Amyloid Formation and Provides Clues to Factors That Modulate Amyloidogenicity.
    Noh D; Bower RL; Hay DL; Zhyvoloup A; Raleigh DP
    ACS Chem Biol; 2020 Jun; 15(6):1408-1416. PubMed ID: 32364695
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Evolutionary Adaptation and Amyloid Formation: Does the Reduced Amyloidogenicity and Cytotoxicity of Ursine Amylin Contribute to the Metabolic Adaption of Bears and Polar Bears?
    Akter R; Abedini A; Ridgway Z; Zhang X; Kleinberg J; Schmidt AM; Raleigh DP
    Isr J Chem; 2017 Jul; 57(7-8):750-761. PubMed ID: 29955200
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Fibril formation and toxicity of the non-amyloidogenic rat amylin peptide.
    Milton NG; Harris JR
    Micron; 2013 Jan; 44():246-53. PubMed ID: 22854213
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Atomic force microscopy reveals defects within mica supported lipid bilayers induced by the amyloidogenic human amylin peptide.
    Green JD; Kreplak L; Goldsbury C; Li Blatter X; Stolz M; Cooper GS; Seelig A; Kistler J; Aebi U
    J Mol Biol; 2004 Sep; 342(3):877-87. PubMed ID: 15342243
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Amylin S20G mutation in Mexican population.
    Garcia-Gonzalez CL; Montoya-Fuentes H; Padilla-Rosas M; Sanchez-Corona J
    Diabetes Res Clin Pract; 2007 Apr; 76(1):146-8. PubMed ID: 16950544
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Protective role of human insulin against the cytotoxicity associated with human mutant S20G islet amyloid polypeptide.
    Morita S; Ueyama M; Sakagashira S; Shimajiri Y; Yamana A; Furuta M; Sanke T
    J Diabetes Investig; 2013 Sep; 4(5):436-44. PubMed ID: 24843692
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The islet amyloid polypeptide (amylin) gene S20G mutation in Chinese subjects: evidence for associations with type 2 diabetes and cholesterol levels.
    Lee SC; Hashim Y; Li JK; Ko GT; Critchley JA; Cockram CS; Chan JC
    Clin Endocrinol (Oxf); 2001 Apr; 54(4):541-6. PubMed ID: 11318791
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.