114 related articles for article (PubMed ID: 11106643)
1. Repression of human reduced folate carrier gene expression by wild type p53.
Ding BC; Whetstine JR; Witt TL; Schuetz JD; Matherly LH
J Biol Chem; 2001 Mar; 276(12):8713-9. PubMed ID: 11106643
[TBL] [Abstract][Full Text] [Related]
2. Primary acute lymphoblastic leukemia cells use a novel promoter and 5'noncoding exon for the human reduced folate carrier that encodes a modified carrier translated from an upstream translational start.
Flatley RM; Payton SG; Taub JW; Matherly LH
Clin Cancer Res; 2004 Aug; 10(15):5111-22. PubMed ID: 15297414
[TBL] [Abstract][Full Text] [Related]
3. Alterations in the expression of transcription factors and the reduced folate carrier as a novel mechanism of antifolate resistance in human leukemia cells.
Rothem L; Aronheim A; Assaraf YG
J Biol Chem; 2003 Mar; 278(11):8935-41. PubMed ID: 12519783
[TBL] [Abstract][Full Text] [Related]
4. The human reduced folate carrier gene is ubiquitously and differentially expressed in normal human tissues: identification of seven non-coding exons and characterization of a novel promoter.
Whetstine JR; Flatley RM; Matherly LH
Biochem J; 2002 Nov; 367(Pt 3):629-40. PubMed ID: 12144527
[TBL] [Abstract][Full Text] [Related]
5. Roles of USF, Ikaros and Sp proteins in the transcriptional regulation of the human reduced folate carrier B promoter.
Liu M; Whetstine JR; Payton SG; Ge Y; Flatley RM; Matherly LH
Biochem J; 2004 Oct; 383(Pt 2):249-57. PubMed ID: 15214842
[TBL] [Abstract][Full Text] [Related]
6. Human K562 transfectants expressing high levels of reduced folate carrier but exhibiting low transport activity.
Wong SC; McQuade R; Proefke SA; Bhushan A; Matherly LH
Biochem Pharmacol; 1997 Jan; 53(2):199-206. PubMed ID: 9037252
[TBL] [Abstract][Full Text] [Related]
7. Association of deletions and translocation of the reduced folate carrier gene with profound loss of gene expression in methotrexate-resistant K562 human erythroleukemia cells.
Ding BC; Witt TL; Hukku B; Heng H; Zhang L; Matherly LH
Biochem Pharmacol; 2001 Mar; 61(6):665-75. PubMed ID: 11266651
[TBL] [Abstract][Full Text] [Related]
8. Reduced folate carrier gene silencing in multiple antifolate-resistant tumor cell lines is due to a simultaneous loss of function of multiple transcription factors but not promoter methylation.
Rothem L; Stark M; Kaufman Y; Mayo L; Assaraf YG
J Biol Chem; 2004 Jan; 279(1):374-84. PubMed ID: 14551190
[TBL] [Abstract][Full Text] [Related]
9. Transcriptional regulation of the human reduced folate carrier in childhood acute lymphoblastic leukemia cells.
Liu M; Ge Y; Payton SG; Aboukameel A; Buck S; Flatley RM; Haska C; Mohammad R; Taub JW; Matherly LH
Clin Cancer Res; 2006 Jan; 12(2):608-16. PubMed ID: 16428507
[TBL] [Abstract][Full Text] [Related]
10. Transcriptional regulation of the human reduced folate carrier promoter C: synergistic transactivation by Sp1 and C/EBP beta and identification of a downstream repressor.
Payton SG; Whetstine JR; Ge Y; Matherly LH
Biochim Biophys Acta; 2005 Jan; 1727(1):45-57. PubMed ID: 15652157
[TBL] [Abstract][Full Text] [Related]
11. The basal promoters for the human reduced folate carrier gene are regulated by a GC-box and a cAMP-response element/AP-1-like element. Basis for tissue-specific gene expression.
Whetstine JR; Matherly LH
J Biol Chem; 2001 Mar; 276(9):6350-8. PubMed ID: 11078737
[TBL] [Abstract][Full Text] [Related]
12. Effects of 5' untranslated region diversity on the posttranscriptional regulation of the human reduced folate carrier.
Payton SG; Haska CL; Flatley RM; Ge Y; Matherly LH
Biochim Biophys Acta; 2007 Feb; 1769(2):131-8. PubMed ID: 17306382
[TBL] [Abstract][Full Text] [Related]
13. Single nucleotide polymorphisms in the human reduced folate carrier: characterization of a high-frequency G/A variant at position 80 and transport properties of the His(27) and Arg(27) carriers.
Whetstine JR; Gifford AJ; Witt T; Liu XY; Flatley RM; Norris M; Haber M; Taub JW; Ravindranath Y; Matherly LH
Clin Cancer Res; 2001 Nov; 7(11):3416-22. PubMed ID: 11705857
[TBL] [Abstract][Full Text] [Related]
14. Identification of lysine-411 in the human reduced folate carrier as an important determinant of substrate selectivity and carrier function by systematic site-directed mutagenesis.
Witt TL; Matherly LH
Biochim Biophys Acta; 2002 Dec; 1567(1-2):56-62. PubMed ID: 12488038
[TBL] [Abstract][Full Text] [Related]
15. The human reduced folate carrier gene is regulated by the AP2 and sp1 transcription factor families and a functional 61-base pair polymorphism.
Whetstine JR; Witt TL; Matherly LH
J Biol Chem; 2002 Nov; 277(46):43873-80. PubMed ID: 12228234
[TBL] [Abstract][Full Text] [Related]
16. A humanized mouse model for the reduced folate carrier.
Patterson D; Graham C; Cherian C; Matherly LH
Mol Genet Metab; 2008 Feb; 93(2):95-103. PubMed ID: 17983788
[TBL] [Abstract][Full Text] [Related]
17. Restoration of high-level transport activity by human reduced folate carrier/ThTr1 thiamine transporter chimaeras: role of the transmembrane domain 6/7 linker region in reduced folate carrier function.
Liu XY; Witt TL; Matherly LH
Biochem J; 2003 Jan; 369(Pt 1):31-7. PubMed ID: 12227830
[TBL] [Abstract][Full Text] [Related]
18. Role of the E45K-reduced folate carrier gene mutation in methotrexate resistance in human leukemia cells.
Gifford AJ; Haber M; Witt TL; Whetstine JR; Taub JW; Matherly LH; Norris MD
Leukemia; 2002 Dec; 16(12):2379-87. PubMed ID: 12454742
[TBL] [Abstract][Full Text] [Related]
19. Folate uptake in the human intestine: promoter activity and effect of folate deficiency.
Subramanian VS; Chatterjee N; Said HM
J Cell Physiol; 2003 Aug; 196(2):403-8. PubMed ID: 12811835
[TBL] [Abstract][Full Text] [Related]
20. Post-transcriptional regulation of the human reduced folate carrier as a novel adaptive mechanism in response to folate excess or deficiency.
Hou Z; Orr S; Matherly LH
Biosci Rep; 2014 Aug; 34(4):. PubMed ID: 24949876
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]