BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

574 related articles for article (PubMed ID: 11114890)

  • 21. Endosulfan induces CYP2B6 and CYP3A4 by activating the pregnane X receptor.
    Casabar RC; Das PC; Dekrey GK; Gardiner CS; Cao Y; Rose RL; Wallace AD
    Toxicol Appl Pharmacol; 2010 Jun; 245(3):335-43. PubMed ID: 20361990
    [TBL] [Abstract][Full Text] [Related]  

  • 22. The pregnane X receptor binds to response elements in a genomic context-dependent manner, and PXR activator rifampicin selectively alters the binding among target genes.
    Song X; Xie M; Zhang H; Li Y; Sachdeva K; Yan B
    Drug Metab Dispos; 2004 Jan; 32(1):35-42. PubMed ID: 14709618
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Human constitutive androstane receptor mediates induction of CYP2B6 gene expression by phenytoin.
    Wang H; Faucette S; Moore R; Sueyoshi T; Negishi M; LeCluyse E
    J Biol Chem; 2004 Jul; 279(28):29295-301. PubMed ID: 15123723
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Reduction in cytochrome P-450 enzyme expression is associated with repression of CAR (constitutive androstane receptor) and PXR (pregnane X receptor) in mouse liver during the acute phase response.
    Beigneux AP; Moser AH; Shigenaga JK; Grunfeld C; Feingold KR
    Biochem Biophys Res Commun; 2002 Apr; 293(1):145-9. PubMed ID: 12054576
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Relative activation of human pregnane X receptor versus constitutive androstane receptor defines distinct classes of CYP2B6 and CYP3A4 inducers.
    Faucette SR; Zhang TC; Moore R; Sueyoshi T; Omiecinski CJ; LeCluyse EL; Negishi M; Wang H
    J Pharmacol Exp Ther; 2007 Jan; 320(1):72-80. PubMed ID: 17041008
    [TBL] [Abstract][Full Text] [Related]  

  • 26. A human immunodeficiency virus protease inhibitor is a novel functional inhibitor of human pregnane X receptor.
    Healan-Greenberg C; Waring JF; Kempf DJ; Blomme EA; Tirona RG; Kim RB
    Drug Metab Dispos; 2008 Mar; 36(3):500-7. PubMed ID: 18096673
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Sterol regulatory element binding protein 1 interacts with pregnane X receptor and constitutive androstane receptor and represses their target genes.
    Roth A; Looser R; Kaufmann M; Meyer UA
    Pharmacogenet Genomics; 2008 Apr; 18(4):325-37. PubMed ID: 18334917
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Coordinated roles of pregnane X receptor and constitutive androstane receptor in autoinduction of voriconazole metabolism in mice.
    Ohbuchi M; Yoshinari K; Kaneko H; Matsumoto S; Inoue A; Kawamura A; Usui T; Yamazoe Y
    Antimicrob Agents Chemother; 2013 Mar; 57(3):1332-8. PubMed ID: 23274663
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Simultaneous assessment of cytochrome P450 activity in cultured human hepatocytes for compound-mediated induction of CYP3A4, CYP2B6, and CYP1A2.
    Rhodes SP; Otten JN; Hingorani GP; Hartley DP; Franklin RB
    J Pharmacol Toxicol Methods; 2011; 63(3):223-6. PubMed ID: 21111054
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Identification of three novel natural product compounds that activate PXR and CAR and inhibit inflammation.
    Kittayaruksakul S; Zhao W; Xu M; Ren S; Lu J; Wang J; Downes M; Evans RM; Venkataramanan R; Chatsudthipong V; Xie W
    Pharm Res; 2013 Sep; 30(9):2199-208. PubMed ID: 23896737
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Modulation of constitutive androstane receptor (CAR) and pregnane X receptor (PXR) by 6-arylpyrrolo[2,1-d][1,5]benzothiazepine derivatives, ligands of peripheral benzodiazepine receptor (PBR).
    Anderson LE; Dring AM; Hamel LD; Stoner MA
    Toxicol Lett; 2011 Apr; 202(2):148-54. PubMed ID: 21315811
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Rat PXR reporter-gene activity correlates with the induction of CYP3A in rat precision-cut liver slices.
    Cui X; Thomas A; Montgomery D; Gu C; Morrison RA; White RE; Cheng KC
    Comb Chem High Throughput Screen; 2005 Jun; 8(4):341-6. PubMed ID: 16101010
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Role of orphan nuclear receptors in the regulation of drug-metabolising enzymes.
    Wang H; LeCluyse EL
    Clin Pharmacokinet; 2003; 42(15):1331-57. PubMed ID: 14674787
    [TBL] [Abstract][Full Text] [Related]  

  • 34. The environmental estrogen, nonylphenol, activates the constitutive androstane receptor.
    Hernandez JP; Huang W; Chapman LM; Chua S; Moore DD; Baldwin WS
    Toxicol Sci; 2007 Aug; 98(2):416-26. PubMed ID: 17483497
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Rat pregnane X receptor: molecular cloning, tissue distribution, and xenobiotic regulation.
    Zhang H; LeCulyse E; Liu L; Hu M; Matoney L; Zhu W; Yan B
    Arch Biochem Biophys; 1999 Aug; 368(1):14-22. PubMed ID: 10415106
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Opposing regulation of cytochrome P450 expression by CAR and PXR in hypothyroid mice.
    Park YJ; Lee EK; Lee YK; Park DJ; Jang HC; Moore DD
    Toxicol Appl Pharmacol; 2012 Sep; 263(2):131-7. PubMed ID: 22503787
    [TBL] [Abstract][Full Text] [Related]  

  • 37. The environmental pollutant 1,1-dichloro-2,2-bis (p-chlorophenyl)ethylene induces rat hepatic cytochrome P450 2B and 3A expression through the constitutive androstane receptor and pregnane X receptor.
    Wyde ME; Bartolucci E; Ueda A; Zhang H; Yan B; Negishi M; You L
    Mol Pharmacol; 2003 Aug; 64(2):474-81. PubMed ID: 12869653
    [TBL] [Abstract][Full Text] [Related]  

  • 38. The pregnane X receptor: a promiscuous xenobiotic receptor that has diverged during evolution.
    Jones SA; Moore LB; Shenk JL; Wisely GB; Hamilton GA; McKee DD; Tomkinson NC; LeCluyse EL; Lambert MH; Willson TM; Kliewer SA; Moore JT
    Mol Endocrinol; 2000 Jan; 14(1):27-39. PubMed ID: 10628745
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Regulation of drug transporter gene expression by nuclear receptors.
    Staudinger JL; Madan A; Carol KM; Parkinson A
    Drug Metab Dispos; 2003 May; 31(5):523-7. PubMed ID: 12695338
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Modulation of mouse and human phenobarbital-responsive enhancer module by nuclear receptors.
    Mäkinen J; Frank C; Jyrkkärinne J; Gynther J; Carlberg C; Honkakoski P
    Mol Pharmacol; 2002 Aug; 62(2):366-78. PubMed ID: 12130690
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 29.