BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

588 related articles for article (PubMed ID: 11123360)

  • 1. mGluR5 antagonists 2-methyl-6-(phenylethynyl)-pyridine and (E)-2-methyl-6-(2-phenylethenyl)-pyridine reduce traumatic neuronal injury in vitro and in vivo by antagonizing N-methyl-D-aspartate receptors.
    Movsesyan VA; O'Leary DM; Fan L; Bao W; Mullins PG; Knoblach SM; Faden AI
    J Pharmacol Exp Ther; 2001 Jan; 296(1):41-7. PubMed ID: 11123360
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Neuroprotective activity of the mGluR5 antagonists MPEP and MTEP against acute excitotoxicity differs and does not reflect actions at mGluR5 receptors.
    Lea PM; Movsesyan VA; Faden AI
    Br J Pharmacol; 2005 Jun; 145(4):527-34. PubMed ID: 15821750
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Selective mGluR5 antagonists MPEP and SIB-1893 decrease NMDA or glutamate-mediated neuronal toxicity through actions that reflect NMDA receptor antagonism.
    O'Leary DM; Movsesyan V; Vicini S; Faden AI
    Br J Pharmacol; 2000 Dec; 131(7):1429-37. PubMed ID: 11090117
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Selective blockade of metabotropic glutamate receptor subtype 5 is neuroprotective.
    Bruno V; Ksiazek I; Battaglia G; Lukic S; Leonhardt T; Sauer D; Gasparini F; Kuhn R; Nicoletti F; Flor PJ
    Neuropharmacology; 2000 Sep; 39(12):2223-30. PubMed ID: 10974306
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Selective blockade of the mGluR1 receptor reduces traumatic neuronal injury in vitro and improvesoOutcome after brain trauma.
    Faden AI; O'Leary DM; Fan L; Bao W; Mullins PG; Movsesyan VA
    Exp Neurol; 2001 Feb; 167(2):435-44. PubMed ID: 11161632
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Neuroprotective effects of the mGlu5R antagonist MPEP towards quinolinic acid-induced striatal toxicity: involvement of pre- and post-synaptic mechanisms and lack of direct NMDA blocking activity.
    Popoli P; Pintor A; Tebano MT; Frank C; Pepponi R; Nazzicone V; Grieco R; Pèzzola A; Reggio R; Minghetti L; De Berardinis MA; Martire A; Potenza RL; Domenici MR; Massotti M
    J Neurochem; 2004 Jun; 89(6):1479-89. PubMed ID: 15189351
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The mGluR5 antagonist 2-methyl-6-(phenylethynyl)-pyridine (MPEP) potentiates PCP-induced cognitive deficits in rats.
    Campbell UC; Lalwani K; Hernandez L; Kinney GG; Conn PJ; Bristow LJ
    Psychopharmacology (Berl); 2004 Sep; 175(3):310-8. PubMed ID: 15024550
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Selective mGluR5 receptor antagonist or agonist provides neuroprotection in a rat model of focal cerebral ischemia.
    Bao WL; Williams AJ; Faden AI; Tortella FC
    Brain Res; 2001 Dec; 922(2):173-9. PubMed ID: 11743947
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Inhibitory effects of MPEP, an mGluR5 antagonist, and memantine, an N-methyl-D-aspartate receptor antagonist, on morphine antinociceptive tolerance in mice.
    Kozela E; Pilc A; Popik P
    Psychopharmacology (Berl); 2003 Jan; 165(3):245-51. PubMed ID: 12442203
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Lowered brain stimulation reward thresholds in rats treated with a combination of caffeine and N-methyl-D-aspartate but not alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate or metabotropic glutamate receptor-5 receptor antagonists.
    Bespalov A; Dravolina O; Belozertseva I; Adamcio B; Zvartau E
    Behav Pharmacol; 2006 Jun; 17(4):295-302. PubMed ID: 16914947
    [TBL] [Abstract][Full Text] [Related]  

  • 11. mGluR5 antagonist-induced psychoactive properties: MTEP drug discrimination, a pharmacologically selective non-NMDA effect with apparent lack of reinforcing properties.
    Swedberg MD; Ellgren M; Raboisson P
    J Pharmacol Exp Ther; 2014 Apr; 349(1):155-64. PubMed ID: 24472725
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Group II metabotropic glutamate receptor activation attenuates traumatic neuronal injury and improves neurological recovery after traumatic brain injury.
    Allen JW; Ivanova SA; Fan L; Espey MG; Basile AS; Faden AI
    J Pharmacol Exp Ther; 1999 Jul; 290(1):112-20. PubMed ID: 10381766
    [TBL] [Abstract][Full Text] [Related]  

  • 13. 2-Methyl-6-(phenylethynyl)-pyridine (MPEP), a potent, selective and systemically active mGlu5 receptor antagonist.
    Gasparini F; Lingenhöhl K; Stoehr N; Flor PJ; Heinrich M; Vranesic I; Biollaz M; Allgeier H; Heckendorn R; Urwyler S; Varney MA; Johnson EC; Hess SD; Rao SP; Sacaan AI; Santori EM; Veliçelebi G; Kuhn R
    Neuropharmacology; 1999 Oct; 38(10):1493-503. PubMed ID: 10530811
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Prolonged blockade of NMDA or mGluR5 glutamate receptors reduces nigrostriatal degeneration while inducing selective metabolic changes in the basal ganglia circuitry in a rodent model of Parkinson's disease.
    Armentero MT; Fancellu R; Nappi G; Bramanti P; Blandini F
    Neurobiol Dis; 2006 Apr; 22(1):1-9. PubMed ID: 16289868
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Subtype selective antagonism of substantia nigra pars compacta Group I metabotropic glutamate receptors protects the nigrostriatal system against 6-hydroxydopamine toxicity in vivo.
    Vernon AC; Zbarsky V; Datla KP; Croucher MJ; Dexter DT
    J Neurochem; 2007 Nov; 103(3):1075-91. PubMed ID: 17714448
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Attenuation of behavioral effects of cocaine by the Metabotropic Glutamate Receptor 5 Antagonist 2-Methyl-6-(phenylethynyl)-pyridine in squirrel monkeys: comparison with dizocilpine.
    Lee B; Platt DM; Rowlett JK; Adewale AS; Spealman RD
    J Pharmacol Exp Ther; 2005 Mar; 312(3):1232-40. PubMed ID: 15550570
    [TBL] [Abstract][Full Text] [Related]  

  • 17. MGLuR5 activation reduces beta-amyloid-induced cell death in primary neuronal cultures and attenuates translocation of cytochrome c and apoptosis-inducing factor.
    Movsesyan VA; Stoica BA; Faden AI
    J Neurochem; 2004 Jun; 89(6):1528-36. PubMed ID: 15189356
    [TBL] [Abstract][Full Text] [Related]  

  • 18. SIB-1757 and SIB-1893: selective, noncompetitive antagonists of metabotropic glutamate receptor type 5.
    Varney MA; Cosford ND; Jachec C; Rao SP; Sacaan A; Lin FF; Bleicher L; Santori EM; Flor PJ; Allgeier H; Gasparini F; Kuhn R; Hess SD; Veliçelebi G; Johnson EC
    J Pharmacol Exp Ther; 1999 Jul; 290(1):170-81. PubMed ID: 10381773
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Neuroprotective effect caused by MPEP, an antagonist of metabotropic glutamate receptor mGluR5, on seizures induced by pilocarpine in 21-day-old rats.
    Jesse CR; Savegnago L; Rocha JB; Nogueira CW
    Brain Res; 2008 Mar; 1198():197-203. PubMed ID: 18242586
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Functional Interaction Between NMDA and mGlu5 Receptors: Effects on Working Memory, Instrumental Learning, Motor Behaviors, and Dopamine Release.
    Homayoun H; Stefani MR; Adams BW; Tamagan GD; Moghaddam B
    Neuropsychopharmacology; 2004 Jul; 29(7):1259-69. PubMed ID: 15010696
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 30.