137 related articles for article (PubMed ID: 11123988)
1. Semisynthesis of antitumoral acetogenins: SAR of functionalized alkyl-chain bis-tetrahydrofuranic acetogenins, specific inhibitors of mitochondrial complex I.
Gallardo T; Zafra-Polo MC; Tormo JR; González MC; Franck X; Estornell E; Cortes D
J Med Chem; 2000 Dec; 43(25):4793-800. PubMed ID: 11123988
[TBL] [Abstract][Full Text] [Related]
2. Gamma-lactone-Functionalized antitumoral acetogenins are the most potent inhibitors of mitochondrial complex I.
Tormo JR; Estornell E; Gallardo T; González MC; Cavé A; Granell S; Cortes D; Zafra-Polo MC
Bioorg Med Chem Lett; 2001 Mar; 11(5):681-4. PubMed ID: 11266168
[TBL] [Abstract][Full Text] [Related]
3. Inhibitory effects on mitochondrial complex I of semisynthetic mono-tetrahydrofuran acetogenin derivatives.
Tormo JR; Gallardo T; Peris E; Bermejo A; Cabedo N; Estornell E; Zafra-Polo MC; Cortes D
Bioorg Med Chem Lett; 2003 Nov; 13(22):4101-5. PubMed ID: 14592516
[TBL] [Abstract][Full Text] [Related]
4. In vitro antitumor structure-activity relationships of threo/trans/threo mono-tetrahydrofuranic acetogenins: correlations with their inhibition of mitochondrial complex I.
Tormo JR; Royo I; Gallardo T; Zafra-Polo MC; Hernández P; Cortes D; Peláez F
Oncol Res; 2003; 14(3):147-54. PubMed ID: 14760863
[TBL] [Abstract][Full Text] [Related]
5. Specific interactions of monotetrahydrofuranic annonaceous acetogenins as inhibitors of mitochondrial complex I.
Tormo JR; Gallardo T; Aragón R; Cortes D; Estornell E
Chem Biol Interact; 1999 Nov; 122(3):171-83. PubMed ID: 10682937
[TBL] [Abstract][Full Text] [Related]
6. Epoxy-acetogenins and other polyketide epoxy derivatives as inhibitors of the mitochondrial respiratory chain complex I.
Tormo JR; Zafra-Polo MC; Serrano A; Estornell E; Cortes D
Planta Med; 2000 May; 66(4):318-23. PubMed ID: 10865446
[TBL] [Abstract][Full Text] [Related]
7. Definition of crucial structural factors of acetogenins, potent inhibitors of mitochondrial complex I.
Takada M; Kuwabara K; Nakato H; Tanaka A; Iwamura H; Miyoshi H
Biochim Biophys Acta; 2000 Nov; 1460(2-3):302-10. PubMed ID: 11106771
[TBL] [Abstract][Full Text] [Related]
8. Design syntheses and mitochondrial complex I inhibitory activity of novel acetogenin mimics.
Kuwabara K; Takada M; Iwata J; Tatsumoto K; Sakamoto K; Iwamura H; Miyoshi H
Eur J Biochem; 2000 May; 267(9):2538-46. PubMed ID: 10785373
[TBL] [Abstract][Full Text] [Related]
9. Guanaconetins, new antitumoral acetogenins, mitochondrial complex I and tumor cell growth inhibitors.
Chahboune N; Barrachina I; Royo I; Romero V; Sáez J; Tormo JR; De Pedro N; Estornell E; Zafra-Polo MC; Peláez F; Cortes D
Bioorg Med Chem; 2006 Feb; 14(4):1089-94. PubMed ID: 16242335
[TBL] [Abstract][Full Text] [Related]
10. Heterocyclic analogues of squamocin as inhibitors of mitochondrial complex I. On the role of the terminal lactone of annonaceous acetogenins.
Duval RA; Lewin G; Peris E; Chahboune N; Garofano A; Dröse S; Cortes D; Brandt U; Hocquemiller R
Biochemistry; 2006 Feb; 45(8):2721-8. PubMed ID: 16489765
[TBL] [Abstract][Full Text] [Related]
11. In vitro antitumor structure-activity relationships of threo/trans/threo/trans/erythro bis-tetrahydrofuranic acetogenins: correlations with their inhibition of mitochondrial complex I.
Tormo JR; DePedro N; Royo I; Barrachina I; Zafra-Polo MC; Cuadrillero C; Hernández P; Cortes D; Peláez F
Oncol Res; 2005; 15(3):129-38. PubMed ID: 16050134
[TBL] [Abstract][Full Text] [Related]
12. Synthesis and inhibitory activity of ubiquinone-acetogenin hybrid inhibitor with bovine mitochondrial complex I.
Yabunaka H; Abe M; Kenmochi A; Hamada T; Nishioka T; Miyoshi H
Bioorg Med Chem Lett; 2003 Jul; 13(14):2385-8. PubMed ID: 12824040
[TBL] [Abstract][Full Text] [Related]
13. Synthesis of (4R,15R,16R,21S)- and (4R,15S,16S,21S)-rollicosin, squamostolide, and their inhibitory action with bovine heart mitochondrial complex I.
Makabe H; Kimura Y; Higuchi M; Konno H; Murai M; Miyoshi H
Bioorg Med Chem; 2006 May; 14(9):3119-30. PubMed ID: 16431114
[TBL] [Abstract][Full Text] [Related]
14. Function of the alkyl side chains of Deltalac-acetogenins in the inhibitory effect on mitochondrial complex I (NADH-ubiquinone oxidoreductase).
Ichimaru N; Abe M; Murai M; Senoh M; Nishioka T; Miyoshi H
Bioorg Med Chem Lett; 2006 Jul; 16(13):3555-8. PubMed ID: 16621539
[TBL] [Abstract][Full Text] [Related]
15. Synthesis and inhibition mechanism of Delta lac-acetogenins, a novel type of inhibitor of bovine heart mitochondrial complex I.
Ichimaru N; Murai M; Abe M; Hamada T; Yamada Y; Makino S; Nishioka T; Makabe H; Makino A; Kobayashi T; Miyoshi H
Biochemistry; 2005 Jan; 44(2):816-25. PubMed ID: 15641810
[TBL] [Abstract][Full Text] [Related]
16. Essential structural features of acetogenins: role of hydroxy groups adjacent to the bis-THF rings.
Abe M; Kenmochi A; Ichimaru N; Hamada T; Nishioka T; Miyoshi H
Bioorg Med Chem Lett; 2004 Feb; 14(3):779-82. PubMed ID: 14741288
[TBL] [Abstract][Full Text] [Related]
17. Essential structural factors of annonaceous acetogenins as potent inhibitors of mitochondrial complex I.
Miyoshi H; Ohshima M; Shimada H; Akagi T; Iwamura H; McLaughlin JL
Biochim Biophys Acta; 1998 Jul; 1365(3):443-52. PubMed ID: 9711297
[TBL] [Abstract][Full Text] [Related]
18. Natural substances (acetogenins) from the family Annonaceae are powerful inhibitors of mitochondrial NADH dehydrogenase (Complex I).
Degli Esposti M; Ghelli A; Ratta M; Cortes D; Estornell E
Biochem J; 1994 Jul; 301 ( Pt 1)(Pt 1):161-7. PubMed ID: 8037664
[TBL] [Abstract][Full Text] [Related]
19. Quinone-annonaceous acetogenins: synthesis and complex I inhibition studies of a new class of natural product hybrids.
Arndt S; Emde U; Bäurle S; Friedrich T; Grubert L; Koert U
Chemistry; 2001 Mar; 7(5):993-1005. PubMed ID: 11303880
[TBL] [Abstract][Full Text] [Related]
20. Semisynthesis and cytotoxicity of amino acetogenins and derivatives.
Duret P; Hocquemiller R; Gantier JC; Figadère B
Bioorg Med Chem; 1999 Sep; 7(9):1821-6. PubMed ID: 10530929
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]