BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

115 related articles for article (PubMed ID: 11134265)

  • 1. P-glycoprotein-mediated drug secretion in mouse proximal tubule perfused in vitro.
    Tsuruoka S; Sugimoto KI; Fujimura A; Imai M; Asano Y; Muto S
    J Am Soc Nephrol; 2001 Jan; 12(1):177-181. PubMed ID: 11134265
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Protein kinase C and phosphatidylinositol 3-kinase independently contribute to P-glycoprotein-mediated drug secretion in the mouse proximal tubule.
    Tsuruoka S; Sugimoto K; Fujimura A; Imai M; Asano Y; Muto S
    Pflugers Arch; 2001 Jun; 442(3):321-8. PubMed ID: 11484761
    [TBL] [Abstract][Full Text] [Related]  

  • 3. MDR1 transporter protects against paraquat-induced toxicity in human and mouse proximal tubule cells.
    Wen X; Gibson CJ; Yang I; Buckley B; Goedken MJ; Richardson JR; Aleksunes LM
    Toxicol Sci; 2014 Oct; 141(2):475-83. PubMed ID: 25015657
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The Differential Absorption of a Series of P-Glycoprotein Substrates in Isolated Perfused Lungs from Mdr1a/1b Genetic Knockout Mice can be Attributed to Distinct Physico-Chemical Properties: an Insight into Predicting Transporter-Mediated, Pulmonary Specific Disposition.
    Price DF; Luscombe CN; Eddershaw PJ; Edwards CD; Gumbleton M
    Pharm Res; 2017 Dec; 34(12):2498-2516. PubMed ID: 28702798
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Absence of P-glycoprotein transport in the pharmacokinetics and toxicity of the herbicide paraquat.
    Lacher SE; Gremaud JN; Skagen K; Steed E; Dalton R; Sugden KD; Cardozo-Pelaez F; Sherwin CM; Woodahl EL
    J Pharmacol Exp Ther; 2014 Feb; 348(2):336-45. PubMed ID: 24297779
    [TBL] [Abstract][Full Text] [Related]  

  • 6. ATP binding cassette transporters in two distinct compartments of the skin contribute to transdermal absorption of a typical substrate.
    Hashimoto N; Nakamichi N; Uwafuji S; Yoshida K; Sugiura T; Tsuji A; Kato Y
    J Control Release; 2013 Jan; 165(1):54-61. PubMed ID: 23089896
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Effect of the ATP-binding cassette drug transporters ABCB1, ABCG2, and ABCC2 on erlotinib hydrochloride (Tarceva) disposition in in vitro and in vivo pharmacokinetic studies employing Bcrp1-/-/Mdr1a/1b-/- (triple-knockout) and wild-type mice.
    Marchetti S; de Vries NA; Buckle T; Bolijn MJ; van Eijndhoven MA; Beijnen JH; Mazzanti R; van Tellingen O; Schellens JH
    Mol Cancer Ther; 2008 Aug; 7(8):2280-7. PubMed ID: 18723475
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Influence of breast cancer resistance protein (Abcg2) and p-glycoprotein (Abcb1a) on the transport of imatinib mesylate (Gleevec) across the mouse blood-brain barrier.
    Bihorel S; Camenisch G; Lemaire M; Scherrmann JM
    J Neurochem; 2007 Sep; 102(6):1749-1757. PubMed ID: 17696988
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Effects of P-glycoprotein on cell volume regulation in mouse proximal tubule.
    Miyata Y; Asano Y; Muto S
    Am J Physiol Renal Physiol; 2001 May; 280(5):F829-37. PubMed ID: 11292625
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Effect of mdr1a P-glycoprotein gene disruption, gender, and substrate concentration on brain uptake of selected compounds.
    Dagenais C; Zong J; Ducharme J; Pollack GM
    Pharm Res; 2001 Jul; 18(7):957-63. PubMed ID: 11496955
    [TBL] [Abstract][Full Text] [Related]  

  • 11. P-gp-induced modulation of regulatory volume increase occurs via PKC in mouse proximal tubule.
    Miyata Y; Okada K; Ishibashi S; Asano Y; Muto S
    Am J Physiol Renal Physiol; 2002 Jan; 282(1):F65-76. PubMed ID: 11739114
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Expression, up-regulation, and transport activity of the multidrug-resistance protein Abcg2 at the mouse blood-brain barrier.
    Cisternino S; Mercier C; Bourasset F; Roux F; Scherrmann JM
    Cancer Res; 2004 May; 64(9):3296-301. PubMed ID: 15126373
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The anthelminthic agent albendazole does not interact with p-glycoprotein.
    Merino G; Alvarez AI; Prieto JG; Kim RB
    Drug Metab Dispos; 2002 Apr; 30(4):365-9. PubMed ID: 11901088
    [TBL] [Abstract][Full Text] [Related]  

  • 14. P-glycoprotein and breast cancer resistance protein affect disposition of tandutinib, a tyrosine kinase inhibitor.
    Yang JJ; Milton MN; Yu S; Liao M; Liu N; Wu JT; Gan L; Balani SK; Lee FW; Prakash S; Xia CQ
    Drug Metab Lett; 2010 Dec; 4(4):201-12. PubMed ID: 20670210
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Peroxisome proliferator-activated receptor alpha (PPARalpha)-mediated regulation of multidrug resistance 2 (Mdr2) expression and function in mice.
    Kok T; Bloks VW; Wolters H; Havinga R; Jansen PL; Staels B; Kuipers F
    Biochem J; 2003 Feb; 369(Pt 3):539-47. PubMed ID: 12381268
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Validation of a P-Glycoprotein (P-gp) Humanized Mouse Model by Integrating Selective Absolute Quantification of Human MDR1, Mouse Mdr1a and Mdr1b Protein Expressions with In Vivo Functional Analysis for Blood-Brain Barrier Transport.
    Sadiq MW; Uchida Y; Hoshi Y; Tachikawa M; Terasaki T; Hammarlund-Udenaes M
    PLoS One; 2015; 10(5):e0118638. PubMed ID: 25932627
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Normal viability and altered pharmacokinetics in mice lacking mdr1-type (drug-transporting) P-glycoproteins.
    Schinkel AH; Mayer U; Wagenaar E; Mol CA; van Deemter L; Smit JJ; van der Valk MA; Voordouw AC; Spits H; van Tellingen O; Zijlmans JM; Fibbe WE; Borst P
    Proc Natl Acad Sci U S A; 1997 Apr; 94(8):4028-33. PubMed ID: 9108099
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Absence or pharmacological blocking of placental P-glycoprotein profoundly increases fetal drug exposure.
    Smit JW; Huisman MT; van Tellingen O; Wiltshire HR; Schinkel AH
    J Clin Invest; 1999 Nov; 104(10):1441-7. PubMed ID: 10562306
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Molecular identification and functional characterization of Mdr1a in rat cholangiocytes.
    Gigliozzi A; Fraioli F; Sundaram P; Lee J; Mennone A; Alvaro D; Boyer JL
    Gastroenterology; 2000 Oct; 119(4):1113-22. PubMed ID: 11040198
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Altered drug disposition of the platelet activating factor antagonist apafant in mdr1a knockout mice.
    Leusch A; Volz A; Müller G; Wagner A; Sauer A; Greischel A; Roth W
    Eur J Pharm Sci; 2002 Aug; 16(3):119-28. PubMed ID: 12128165
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.