BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

484 related articles for article (PubMed ID: 11136296)

  • 1. The xenobiotic inhibitor profile of cytochrome P4502C8.
    Ong CE; Coulter S; Birkett DJ; Bhasker CR; Miners JO
    Br J Clin Pharmacol; 2000 Dec; 50(6):573-80. PubMed ID: 11136296
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Kinetic characterization and identification of the enzymes responsible for the hepatic biotransformation of adinazolam and N-desmethyladinazolam in man.
    Venkatakrishnan K; von Moltke LL; Duan SX; Fleishaker JC; Shader RI; Greenblatt DJ
    J Pharm Pharmacol; 1998 Mar; 50(3):265-74. PubMed ID: 9600717
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Trimethoprim and sulfamethoxazole are selective inhibitors of CYP2C8 and CYP2C9, respectively.
    Wen X; Wang JS; Backman JT; Laitila J; Neuvonen PJ
    Drug Metab Dispos; 2002 Jun; 30(6):631-5. PubMed ID: 12019187
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The multidrug resistance modulator valspodar (PSC 833) is metabolized by human cytochrome P450 3A. Implications for drug-drug interactions and pharmacological activity of the main metabolite.
    Fischer V; Rodríguez-Gascón A; Heitz F; Tynes R; Hauck C; Cohen D; Vickers AE
    Drug Metab Dispos; 1998 Aug; 26(8):802-11. PubMed ID: 9698296
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Differential selectivity of cytochrome P450 inhibitors against probe substrates in human and rat liver microsomes.
    Eagling VA; Tjia JF; Back DJ
    Br J Clin Pharmacol; 1998 Feb; 45(2):107-14. PubMed ID: 9491822
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Evidence for involvement of human CYP3A in the 3-hydroxylation of quinine.
    Zhang H; Coville PF; Walker RJ; Miners JO; Birkett DJ; Wanwimolruk S
    Br J Clin Pharmacol; 1997 Mar; 43(3):245-52. PubMed ID: 9088578
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Identification of the cytochrome P450 enzymes involved in the N-demethylation of sildenafil.
    Hyland R; Roe EG; Jones BC; Smith DA
    Br J Clin Pharmacol; 2001 Mar; 51(3):239-48. PubMed ID: 11298070
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Metabolic interactions between mibefradil and HMG-CoA reductase inhibitors: an in vitro investigation with human liver preparations.
    Prueksaritanont T; Ma B; Tang C; Meng Y; Assang C; Lu P; Reider PJ; Lin JH; Baillie TA
    Br J Clin Pharmacol; 1999 Mar; 47(3):291-8. PubMed ID: 10215754
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Effects of arachidonic acid, prostaglandins, retinol, retinoic acid and cholecalciferol on xenobiotic oxidations catalysed by human cytochrome P450 enzymes.
    Yamazaki H; Shimada T
    Xenobiotica; 1999 Mar; 29(3):231-41. PubMed ID: 10219964
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Midazolam and triazolam biotransformation in mouse and human liver microsomes: relative contribution of CYP3A and CYP2C isoforms.
    Perloff MD; von Moltke LL; Court MH; Kotegawa T; Shader RI; Greenblatt DJ
    J Pharmacol Exp Ther; 2000 Feb; 292(2):618-28. PubMed ID: 10640299
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Indications for the involvement of a CYP3A-like iso-enzyme in the metabolism of chlorobornane (Toxaphene) congeners in seals from inhibition studies with liver microsomes.
    van Hezik CM; Letcher RJ; de Geus HJ; Wester PG; Goksøyr A; Lewis WE; Boon JP
    Aquat Toxicol; 2001 Jan; 51(3):319-33. PubMed ID: 11090893
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Effect of inhibitor depletion on inhibitory potency: tight binding inhibition of CYP3A by clotrimazole.
    Gibbs MA; Kunze KL; Howald WN; Thummel KE
    Drug Metab Dispos; 1999 May; 27(5):596-9. PubMed ID: 10220488
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Confirmation that cytochrome P450 2C8 (CYP2C8) plays a minor role in (S)-(+)- and (R)-(-)-ibuprofen hydroxylation in vitro.
    Chang SY; Li W; Traeger SC; Wang B; Cui D; Zhang H; Wen B; Rodrigues AD
    Drug Metab Dispos; 2008 Dec; 36(12):2513-22. PubMed ID: 18787056
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Role of cytochrome P-4502C9 in irbesartan oxidation by human liver microsomes.
    Bourrié M; Meunier V; Berger Y; Fabre G
    Drug Metab Dispos; 1999 Feb; 27(2):288-96. PubMed ID: 9929518
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Inhibition of human drug metabolizing cytochromes P450 by anastrozole, a potent and selective inhibitor of aromatase.
    Grimm SW; Dyroff MC
    Drug Metab Dispos; 1997 May; 25(5):598-602. PubMed ID: 9152599
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Characterization of the cytochrome P450 enzymes involved in the in vitro metabolism of rosiglitazone.
    Baldwin SJ; Clarke SE; Chenery RJ
    Br J Clin Pharmacol; 1999 Sep; 48(3):424-32. PubMed ID: 10510156
    [TBL] [Abstract][Full Text] [Related]  

  • 17. In vitro metabolism of chloroquine: identification of CYP2C8, CYP3A4, and CYP2D6 as the main isoforms catalyzing N-desethylchloroquine formation.
    Projean D; Baune B; Farinotti R; Flinois JP; Beaune P; Taburet AM; Ducharme J
    Drug Metab Dispos; 2003 Jun; 31(6):748-54. PubMed ID: 12756207
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Oxidation of troglitazone to a quinone-type metabolite catalyzed by cytochrome P-450 2C8 and P-450 3A4 in human liver microsomes.
    Yamazaki H; Shibata A; Suzuki M; Nakajima M; Shimada N; Guengerich FP; Yokoi T
    Drug Metab Dispos; 1999 Nov; 27(11):1260-6. PubMed ID: 10534310
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Metabolism of irinotecan (CPT-11) by human hepatic microsomes: participation of cytochrome P-450 3A and drug interactions.
    Haaz MC; Rivory L; Riché C; Vernillet L; Robert J
    Cancer Res; 1998 Feb; 58(3):468-72. PubMed ID: 9458091
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Comparison of CYP3A activities in a subclone of Caco-2 cells (TC7) and human intestine.
    Raeissi SD; Guo Z; Dobson GL; Artursson P; Hidalgo IJ
    Pharm Res; 1997 Aug; 14(8):1019-25. PubMed ID: 9279883
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 25.