288 related articles for article (PubMed ID: 11146161)
1. Variable cytotoxicity of diphtheria toxin 388-granulocyte-macrophage colony-stimulating factor fusion protein for acute myelogenous leukemia stem cells.
Feuring-Buske M; Frankel A; Gerhard B; Hogge D
Exp Hematol; 2000 Dec; 28(12):1390-400. PubMed ID: 11146161
[TBL] [Abstract][Full Text] [Related]
2. DT388-GM-CSF, a novel fusion toxin consisting of a truncated diphtheria toxin fused to human granulocyte-macrophage colony-stimulating factor, prolongs host survival in a SCID mouse model of acute myeloid leukemia.
Hall PD; Willingham MC; Kreitman RJ; Frankel AE
Leukemia; 1999 Apr; 13(4):629-33. PubMed ID: 10214872
[TBL] [Abstract][Full Text] [Related]
3. Diphtheria toxin fused to granulocyte-macrophage colony-stimulating factor eliminates acute myeloid leukemia cells with the potential to initiate leukemia in immunodeficient mice, but spares normal hemopoietic stem cells.
Terpstra W; Rozemuller H; Breems DA; Rombouts EJ; Prins A; FitzGerald DJ; Kreitman RJ; Wielenga JJ; Ploemacher RE; Löwenberg B; Hagenbeek A; Martens AC
Blood; 1997 Nov; 90(9):3735-42. PubMed ID: 9345060
[TBL] [Abstract][Full Text] [Related]
4. Malignant progenitors from patients with acute myelogenous leukemia are sensitive to a diphtheria toxin-granulocyte-macrophage colony-stimulating factor fusion protein.
Hogge DE; Willman CL; Kreitman RJ; Berger M; Hall PD; Kopecky KJ; McLain C; Tagge EP; Eaves CJ; Frankel AE
Blood; 1998 Jul; 92(2):589-95. PubMed ID: 9657759
[TBL] [Abstract][Full Text] [Related]
5. A diphtheria toxin-interleukin 3 fusion protein is cytotoxic to primitive acute myeloid leukemia progenitors but spares normal progenitors.
Feuring-Buske M; Frankel AE; Alexander RL; Gerhard B; Hogge DE
Cancer Res; 2002 Mar; 62(6):1730-6. PubMed ID: 11912147
[TBL] [Abstract][Full Text] [Related]
6. Diphtheria toxin fused to granulocyte-macrophage colony-stimulating factor is toxic to blasts from patients with juvenile myelomonocytic leukemia and chronic myelomonocytic leukemia.
Frankel AE; Lilly M; Kreitman R; Hogge D; Beran M; Freedman MH; Emanuel PD; McLain C; Hall P; Tagge E; Berger M; Eaves C
Blood; 1998 Dec; 92(11):4279-86. PubMed ID: 9834234
[TBL] [Abstract][Full Text] [Related]
7. A recombinant fusion toxin targeted to the granulocyte-macrophage colony-stimulating factor receptor.
Bendel AE; Shao Y; Davies SM; Warman B; Yang CH; Waddick KG; Uckun FM; Perentesis JP
Leuk Lymphoma; 1997 Apr; 25(3-4):257-70. PubMed ID: 9168436
[TBL] [Abstract][Full Text] [Related]
8. Toxicology and pharmacokinetics of DT388-GM-CSF, a fusion toxin consisting of a truncated diphtheria toxin (DT388) linked to human granulocyte-macrophage colony-stimulating factor (GM-CSF) in C57BL/6 mice.
Hall PD; Kreitman RJ; Willingham MC; Frankel AE
Toxicol Appl Pharmacol; 1998 May; 150(1):91-7. PubMed ID: 9630457
[TBL] [Abstract][Full Text] [Related]
9. Improved engraftment of human acute myeloid leukemia progenitor cells in beta 2-microglobulin-deficient NOD/SCID mice and in NOD/SCID mice transgenic for human growth factors.
Feuring-Buske M; Gerhard B; Cashman J; Humphries RK; Eaves CJ; Hogge DE
Leukemia; 2003 Apr; 17(4):760-3. PubMed ID: 12682634
[TBL] [Abstract][Full Text] [Related]
10. A murine cytokine fusion toxin specifically targeting the murine granulocyte-macrophage colony-stimulating factor (GM-CSF) receptor on normal committed bone marrow progenitor cells and GM-CSF-dependent tumor cells.
Chan CH; Blazar BR; Eide CR; Kreitman RJ; Vallera DA
Blood; 1995 Oct; 86(7):2732-40. PubMed ID: 7670112
[TBL] [Abstract][Full Text] [Related]
11. Acute myeloid leukemia cells in G0 phase of the cell cycle that are unresponsive to conventional chemotherapy are sensitive to treatment with granulocyte-macrophage colony-stimulating factor/diphtheria toxin fusion proteins.
Jedema I; Barge RM; Frankel AE; Willemze R; Falkenburg JH
Exp Hematol; 2004 Feb; 32(2):188-94. PubMed ID: 15102480
[TBL] [Abstract][Full Text] [Related]
12. Modulation of the apoptotic response of human myeloid leukemia cells to a diphtheria toxin granulocyte-macrophage colony-stimulating factor fusion protein.
Frankel AE; Hall PD; Burbage C; Vesely J; Willingham M; Bhalla K; Kreitman RJ
Blood; 1997 Nov; 90(9):3654-61. PubMed ID: 9345050
[TBL] [Abstract][Full Text] [Related]
13. Retroviral marking of acute myelogenous leukemia progenitors that initiate long-term culture and growth in immunodeficient mice.
Ailles LE; Humphries RK; Thomas TE; Hogge DE
Exp Hematol; 1999 Nov; 27(11):1609-20. PubMed ID: 10560908
[TBL] [Abstract][Full Text] [Related]
14. Detection and characterization of primitive malignant and normal progenitors in patients with acute myelogenous leukemia using long-term coculture with supportive feeder layers and cytokines.
Ailles LE; Gerhard B; Hogge DE
Blood; 1997 Oct; 90(7):2555-64. PubMed ID: 9326221
[TBL] [Abstract][Full Text] [Related]
15. GM-CSF receptor targeted treatment of primary AML in SCID mice using Diphtheria toxin fused to huGM-CSF.
Rozemuller H; Terpstra W; Rombouts EJ; Lawler M; Byrne C; FitzGerald DJ; Kreitman RJ; Wielenga JJ; Löwenberg B; Touw IP; Hagenbeek A; Martens AC
Leukemia; 1998 Dec; 12(12):1962-70. PubMed ID: 9844926
[TBL] [Abstract][Full Text] [Related]
16. Growth characteristics of acute myelogenous leukemia progenitors that initiate malignant hematopoiesis in nonobese diabetic/severe combined immunodeficient mice.
Ailles LE; Gerhard B; Kawagoe H; Hogge DE
Blood; 1999 Sep; 94(5):1761-72. PubMed ID: 10477702
[TBL] [Abstract][Full Text] [Related]
17. Phase I trial of a novel diphtheria toxin/granulocyte macrophage colony-stimulating factor fusion protein (DT388GMCSF) for refractory or relapsed acute myeloid leukemia.
Frankel AE; Powell BL; Hall PD; Case LD; Kreitman RJ
Clin Cancer Res; 2002 May; 8(5):1004-13. PubMed ID: 12006512
[TBL] [Abstract][Full Text] [Related]
18. Recombinant toxins containing human granulocyte-macrophage colony-stimulating factor and either pseudomonas exotoxin or diphtheria toxin kill gastrointestinal cancer and leukemia cells.
Kreitman RJ; Pastan I
Blood; 1997 Jul; 90(1):252-9. PubMed ID: 9207460
[TBL] [Abstract][Full Text] [Related]
19. Cytotoxicity of a recombinant diphtheria toxin-granulocyte colony-stimulating factor fusion protein on human leukemic blast cells.
Chadwick DE; Williams DP; Niho Y; Murphy JR; Minden MD
Leuk Lymphoma; 1993 Oct; 11(3-4):249-62. PubMed ID: 7505148
[TBL] [Abstract][Full Text] [Related]
20. Proliferative response of human acute myeloid leukemia cells and normal marrow enriched progenitor cells to human recombinant growth factors IL-3, GM-CSF and G-CSF alone and in combination.
Lemoli RM; Gulati SC; Strife A; Lambek C; Perez A; Clarkson BD
Leukemia; 1991 May; 5(5):386-91. PubMed ID: 1709711
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
