BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

381 related articles for article (PubMed ID: 11150170)

  • 1. D-Amino acid scan of gamma-melanocyte-stimulating hormone: importance of Trp(8) on human MC3 receptor selectivity.
    Grieco P; Balse PM; Weinberg D; MacNeil T; Hruby VJ
    J Med Chem; 2000 Dec; 43(26):4998-5002. PubMed ID: 11150170
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Cyclic lactam alpha-melanotropin analogues of Ac-Nle4-cyclo[Asp5, D-Phe7,Lys10] alpha-melanocyte-stimulating hormone-(4-10)-NH2 with bulky aromatic amino acids at position 7 show high antagonist potency and selectivity at specific melanocortin receptors.
    Hruby VJ; Lu D; Sharma SD; Castrucci AL; Kesterson RA; al-Obeidi FA; Hadley ME; Cone RD
    J Med Chem; 1995 Sep; 38(18):3454-61. PubMed ID: 7658432
    [TBL] [Abstract][Full Text] [Related]  

  • 3. γ₂-Melanocyte stimulation hormone (γ₂-MSH) truncation studies results in the cautionary note that γ₂-MSH is not selective for the mouse MC3R over the mouse MC5R.
    Joseph CG; Yao H; Scott JW; Sorensen NB; Marnane RN; Mountjoy KG; Haskell-Luevano C
    Peptides; 2010 Dec; 31(12):2304-13. PubMed ID: 20833220
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Structure-activity relationships of the melanocortin tetrapeptide Ac-His-D-Phe-Arg-Trp-NH2 at the mouse melanocortin receptors. 4. Modifications at the Trp position.
    Holder JR; Xiang Z; Bauzo RM; Haskell-Luevano C
    J Med Chem; 2002 Dec; 45(26):5736-44. PubMed ID: 12477357
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Synthesis and biological evaluation on hMC3, hMC4 and hMC5 receptors of gamma-MSH analogs substituted with L-alanine.
    Grieco P; Balse-Srinivasan P; Han G; Weinberg D; MacNeil T; Van der Ploeg LH; Hruby VJ
    J Pept Res; 2002 May; 59(5):203-10. PubMed ID: 11966977
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Structure-activity relationships of novel cyclic alpha-MSH/beta-MSH hybrid analogues that lead to potent and selective ligands for the human MC3R and human MC5R.
    Balse-Srinivasan P; Grieco P; Cai M; Trivedi D; Hruby VJ
    J Med Chem; 2003 Aug; 46(17):3728-33. PubMed ID: 12904077
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Structure-activity relationships of the melanocortin tetrapeptide Ac-His-DPhe-Arg-Trp-NH(2) at the mouse melanocortin receptors. 1. Modifications at the His position.
    Holder JR; Bauzo RM; Xiang Z; Haskell-Luevano C
    J Med Chem; 2002 Jun; 45(13):2801-10. PubMed ID: 12061882
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Structure-activity relationships of the melanocortin tetrapeptide Ac-His-DPhe-Arg-Trp-NH(2) at the mouse melanocortin receptors: part 2 modifications at the Phe position.
    Holder JR; Bauzo RM; Xiang Z; Haskell-Luevano C
    J Med Chem; 2002 Jul; 45(14):3073-81. PubMed ID: 12086493
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Characterization of melanocortin NDP-MSH agonist peptide fragments at the mouse central and peripheral melanocortin receptors.
    Haskell-Luevano C; Holder JR; Monck EK; Bauzo RM
    J Med Chem; 2001 Jun; 44(13):2247-52. PubMed ID: 11405661
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Structure-activity relationships of gamma-MSH analogues at the human melanocortin MC3, MC4, and MC5 receptors. Discovery of highly selective hMC3R, hMC4R, and hMC5R analogues.
    Balse-Srinivasan P; Grieco P; Cai M; Trivedi D; Hruby VJ
    J Med Chem; 2003 Nov; 46(23):4965-73. PubMed ID: 14584947
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Structure-activity relationships of the melanocortin tetrapeptide Ac-His-DPhe-Arg-Trp-NH2 at the mouse melanocortin receptors. Part 3: modifications at the Arg position.
    Holder JR; Xiang Z; Bauzo RM; Haskell-Luevano C
    Peptides; 2003 Jan; 24(1):73-82. PubMed ID: 12576087
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Conformation of the core sequence in melanocortin peptides directs selectivity for the melanocortin MC3 and MC4 receptors.
    Oosterom J; Nijenhuis WA; Schaaper WM; Slootstra J; Meloen RH; Gispen WH; Burbach JP; Adan RA
    J Biol Chem; 1999 Jun; 274(24):16853-60. PubMed ID: 10358030
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Differential regulation of cAMP-mediated gene transcription and ligand selectivity by MC3R and MC4R melanocortin receptors.
    Lee EJ; Lee SH; Jung JW; Lee W; Kim BJ; Park KW; Lim SK; Yoon CJ; Baik JH
    Eur J Biochem; 2001 Feb; 268(3):582-91. PubMed ID: 11168397
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Type I beta-turn conformation is important for biological activity of the melanocyte-stimulating hormone analogues.
    Li SZ; Lee JH; Lee W; Yoon CJ; Baik JH; Lim SK
    Eur J Biochem; 1999 Oct; 265(1):430-40. PubMed ID: 10491201
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Common requirements for melanocortin-4 receptor selectivity of structurally unrelated melanocortin agonist and endogenous antagonist, Agouti protein.
    Oosterom J; Garner KM; den Dekker WK ; Nijenhuis WA; Gispen WH; Burbach JP; Barsh GS; Adan RA
    J Biol Chem; 2001 Jan; 276(2):931-6. PubMed ID: 11024027
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Identification of putative agouti-related protein(87-132)-melanocortin-4 receptor interactions by homology molecular modeling and validation using chimeric peptide ligands.
    Wilczynski A; Wang XS; Joseph CG; Xiang Z; Bauzo RM; Scott JW; Sorensen NB; Shaw AM; Millard WJ; Richards NG; Haskell-Luevano C
    J Med Chem; 2004 Apr; 47(9):2194-207. PubMed ID: 15084118
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Minimization of MC1R selectivity by modification of the core structure of alpha-MSH-ND.
    Lim S; Li S; Lee C; Yoon C; Baik J; Lee W
    Chem Biol; 2001 Sep; 8(9):857-70. PubMed ID: 11564554
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Cloning of two melanocortin (MC) receptors in spiny dogfish: MC3 receptor in cartilaginous fish shows high affinity to ACTH-derived peptides while it has lower preference to gamma-MSH.
    Klovins J; Haitina T; Ringholm A; Löwgren M; Fridmanis D; Slaidina M; Stier S; Schiöth HB
    Eur J Biochem; 2004 Nov; 271(21):4320-31. PubMed ID: 15511238
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Discovery of prototype peptidomimetic agonists at the human melanocortin receptors MC1R and MC4R.
    Haskell-Luevano C; Hendrata S; North C; Sawyer TK; Hadley ME; Hruby VJ; Dickinson C; Gantz I
    J Med Chem; 1997 Jul; 40(14):2133-9. PubMed ID: 9216831
    [TBL] [Abstract][Full Text] [Related]  

  • 20. [D-Trp8]-gamma-melanocyte-stimulating hormone exhibits anti-inflammatory efficacy in mice bearing a nonfunctional MC1R (recessive yellow e/e mouse).
    Getting SJ; Lam CW; Leoni G; Gavins FN; Grieco P; Perretti M
    Mol Pharmacol; 2006 Dec; 70(6):1850-5. PubMed ID: 16959942
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 20.