252 related articles for article (PubMed ID: 11152688)
1. Post-translational processing of beta-secretase (beta-amyloid-converting enzyme) and its ectodomain shedding. The pro- and transmembrane/cytosolic domains affect its cellular activity and amyloid-beta production.
Benjannet S; Elagoz A; Wickham L; Mamarbachi M; Munzer JS; Basak A; Lazure C; Cromlish JA; Sisodia S; Checler F; Chrétien M; Seidah NG
J Biol Chem; 2001 Apr; 276(14):10879-87. PubMed ID: 11152688
[TBL] [Abstract][Full Text] [Related]
2. A non-amyloidogenic function of BACE-2 in the secretory pathway.
Fluhrer R; Capell A; Westmeyer G; Willem M; Hartung B; Condron MM; Teplow DB; Haass C; Walter J
J Neurochem; 2002 Jun; 81(5):1011-20. PubMed ID: 12065613
[TBL] [Abstract][Full Text] [Related]
3. Apical sorting of beta-secretase limits amyloid beta-peptide production.
Capell A; Meyn L; Fluhrer R; Teplow DB; Walter J; Haass C
J Biol Chem; 2002 Feb; 277(7):5637-43. PubMed ID: 11741885
[TBL] [Abstract][Full Text] [Related]
4. Beta-secretase cleavage at amino acid residue 34 in the amyloid beta peptide is dependent upon gamma-secretase activity.
Shi XP; Tugusheva K; Bruce JE; Lucka A; Wu GX; Chen-Dodson E; Price E; Li Y; Xu M; Huang Q; Sardana MK; Hazuda DJ
J Biol Chem; 2003 Jun; 278(23):21286-94. PubMed ID: 12665519
[TBL] [Abstract][Full Text] [Related]
5. Exclusively targeting beta-secretase to lipid rafts by GPI-anchor addition up-regulates beta-site processing of the amyloid precursor protein.
Cordy JM; Hussain I; Dingwall C; Hooper NM; Turner AJ
Proc Natl Acad Sci U S A; 2003 Sep; 100(20):11735-40. PubMed ID: 14504402
[TBL] [Abstract][Full Text] [Related]
6. A furin-like convertase mediates propeptide cleavage of BACE, the Alzheimer's beta -secretase.
Bennett BD; Denis P; Haniu M; Teplow DB; Kahn S; Louis JC; Citron M; Vassar R
J Biol Chem; 2000 Dec; 275(48):37712-7. PubMed ID: 10956649
[TBL] [Abstract][Full Text] [Related]
7. Failure of the interaction between presenilin 1 and the substrate of gamma-secretase to produce Abeta in insect cells.
Pitsi D; Kienlen-Campard P; Octave JN
J Neurochem; 2002 Oct; 83(2):390-9. PubMed ID: 12423249
[TBL] [Abstract][Full Text] [Related]
8. Interaction of the cytosolic domains of sorLA/LR11 with the amyloid precursor protein (APP) and beta-secretase beta-site APP-cleaving enzyme.
Spoelgen R; von Arnim CA; Thomas AV; Peltan ID; Koker M; Deng A; Irizarry MC; Andersen OM; Willnow TE; Hyman BT
J Neurosci; 2006 Jan; 26(2):418-28. PubMed ID: 16407538
[TBL] [Abstract][Full Text] [Related]
9. Characterization of Alzheimer's beta -secretase protein BACE. A pepsin family member with unusual properties.
Haniu M; Denis P; Young Y; Mendiaz EA; Fuller J; Hui JO; Bennett BD; Kahn S; Ross S; Burgess T; Katta V; Rogers G; Vassar R; Citron M
J Biol Chem; 2000 Jul; 275(28):21099-106. PubMed ID: 10887202
[TBL] [Abstract][Full Text] [Related]
10. The metabolism of beta-amyloid converting enzyme and beta-amyloid precursor protein processing.
Benjannet S; Cromlish JA; Diallo K; Chrétien M; Seidah NG
Biochem Biophys Res Commun; 2004 Dec; 325(1):235-42. PubMed ID: 15522224
[TBL] [Abstract][Full Text] [Related]
11. Processing of beta-secretase by furin and other members of the proprotein convertase family.
Creemers JW; Ines Dominguez D; Plets E; Serneels L; Taylor NA; Multhaup G; Craessaerts K; Annaert W; De Strooper B
J Biol Chem; 2001 Feb; 276(6):4211-7. PubMed ID: 11071887
[TBL] [Abstract][Full Text] [Related]
12. The disulphide bonds in the catalytic domain of BACE are critical but not essential for amyloid precursor protein processing activity.
Fischer F; Molinari M; Bodendorf U; Paganetti P
J Neurochem; 2002 Mar; 80(6):1079-88. PubMed ID: 11953458
[TBL] [Abstract][Full Text] [Related]
13. Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE.
Vassar R; Bennett BD; Babu-Khan S; Kahn S; Mendiaz EA; Denis P; Teplow DB; Ross S; Amarante P; Loeloff R; Luo Y; Fisher S; Fuller J; Edenson S; Lile J; Jarosinski MA; Biere AL; Curran E; Burgess T; Louis JC; Collins F; Treanor J; Rogers G; Citron M
Science; 1999 Oct; 286(5440):735-41. PubMed ID: 10531052
[TBL] [Abstract][Full Text] [Related]
14. BACE knockout mice are healthy despite lacking the primary beta-secretase activity in brain: implications for Alzheimer's disease therapeutics.
Roberds SL; Anderson J; Basi G; Bienkowski MJ; Branstetter DG; Chen KS; Freedman SB; Frigon NL; Games D; Hu K; Johnson-Wood K; Kappenman KE; Kawabe TT; Kola I; Kuehn R; Lee M; Liu W; Motter R; Nichols NF; Power M; Robertson DW; Schenk D; Schoor M; Shopp GM; Shuck ME; Sinha S; Svensson KA; Tatsuno G; Tintrup H; Wijsman J; Wright S; McConlogue L
Hum Mol Genet; 2001 Jun; 10(12):1317-24. PubMed ID: 11406613
[TBL] [Abstract][Full Text] [Related]
15. Degradation of BACE by the ubiquitin-proteasome pathway.
Qing H; Zhou W; Christensen MA; Sun X; Tong Y; Song W
FASEB J; 2004 Oct; 18(13):1571-3. PubMed ID: 15289451
[TBL] [Abstract][Full Text] [Related]
16. Amyloid precursor protein compartmentalization restricts beta-amyloid production: therapeutic targets based on BACE compartmentalization.
Gandhi S; Refolo LM; Sambamurti K
J Mol Neurosci; 2004; 24(1):137-43. PubMed ID: 15314262
[TBL] [Abstract][Full Text] [Related]
17. Cysteine proteases are the major beta-secretase in the regulated secretory pathway that provides most of the beta-amyloid in Alzheimer's disease: role of BACE 1 in the constitutive secretory pathway.
Hook VY; Reisine TD
J Neurosci Res; 2003 Nov; 74(3):393-405. PubMed ID: 14598316
[TBL] [Abstract][Full Text] [Related]
18. Recombinant insect cell expression and purification of human beta-secretase (BACE-1) for X-ray crystallography.
Bruinzeel W; Yon J; Giovannelli S; Masure S
Protein Expr Purif; 2002 Oct; 26(1):139-48. PubMed ID: 12356481
[TBL] [Abstract][Full Text] [Related]
19. Expression of human beta-secretase in the mouse brain increases the steady-state level of beta-amyloid.
Bodendorf U; Danner S; Fischer F; Stefani M; Sturchler-Pierrat C; Wiederhold KH; Staufenbiel M; Paganetti P
J Neurochem; 2002 Mar; 80(5):799-806. PubMed ID: 11948243
[TBL] [Abstract][Full Text] [Related]
20. Maturation and pro-peptide cleavage of beta-secretase.
Capell A; Steiner H; Willem M; Kaiser H; Meyer C; Walter J; Lammich S; Multhaup G; Haass C
J Biol Chem; 2000 Oct; 275(40):30849-54. PubMed ID: 10801872
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
