BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

501 related articles for article (PubMed ID: 11162315)

  • 1. Generation of dual resistance to 4-hydroperoxycyclophosphamide and methotrexate by retroviral transfer of the human aldehyde dehydrogenase class 1 gene and a mutated dihydrofolate reductase gene.
    Takebe N; Zhao SC; Adhikari D; Mineishi S; Sadelain M; Hilton J; Colvin M; Banerjee D; Bertino JR
    Mol Ther; 2001 Jan; 3(1):88-96. PubMed ID: 11162315
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Methotrexate selection of long-term culture initiating cells following transduction of CD34(+) cells with a retrovirus containing a mutated human dihydrofolate reductase gene.
    Takebe N; Xu LC; MacKenzie KL; Bertino JR; Moore MA
    Cancer Gene Ther; 2002 Mar; 9(3):308-20. PubMed ID: 11896448
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Comparison of methotrexate resistance conferred by a mutated dihydrofolate reductase (DHFR) cDNA in two different retroviral vectors.
    Takebe N; Nakahara S; Zhao SC; Adhikari D; Ural AU; Iwamoto M; Banerjee D; Bertino JR
    Cancer Gene Ther; 2000 Jun; 7(6):910-9. PubMed ID: 10880023
    [TBL] [Abstract][Full Text] [Related]  

  • 4. [Mice transduced with double-mutant dihydrofolate reductase-cytidine deaminase fusion gene attained protection from high dose chemotherapy].
    Lu P; Lu Y; Pang K; Wang SB; Chen JQ; Xu HM; Wang JK; Zhao SC
    Zhonghua Wai Ke Za Zhi; 2005 Aug; 43(15):998-1001. PubMed ID: 16194358
    [TBL] [Abstract][Full Text] [Related]  

  • 5. [Double-mutant dihydrofolate reductase gene transfection into bone marrow cells protects mice from chemotherapy].
    Gao HD; Lu P; Lu Y; Pang K; Xu HM; Wang SB; Chen JQ; Zhao SC
    Zhonghua Zhong Liu Za Zhi; 2006 Aug; 28(8):583-5. PubMed ID: 17236551
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Selective expression of methotrexate-resistant dihydrofolate reductase (DHFR) activity in mice transduced with DHFR retrovirus and administered methotrexate.
    Vinh DB; McIvor RS
    J Pharmacol Exp Ther; 1993 Nov; 267(2):989-96. PubMed ID: 8246174
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Protection of hematopoietic stem cells from pemetrexed toxicity by retroviral gene transfer with a mutant dihydrofolate reductase-mutant thymidylate synthase fusion gene.
    Capiaux GM; Budak-Alpdogan T; Alpdogan O; Bornmann W; Takebe N; Banerjee D; Maley F; Bertino JR
    Cancer Gene Ther; 2004 Dec; 11(12):767-73. PubMed ID: 15359285
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Purine salvage rescue by xanthine-guanine phosphoribosyltransferase (XGPRT) potentiates methotrexate resistance conferred by transfer of a mutated dihydrofolate reductase gene.
    Mineishi S; Nakahara S; Takebe N; Zhao SC; Banerjee D; Bertino JR
    Cancer Gene Ther; 1998; 5(3):144-9. PubMed ID: 9622097
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Retrovirally mediated gene transfer of Arg22 and Tyr22 forms of dihydrofolate reductase into the hematopoietic cell line K562: a comparison of methotrexate resistance.
    Braun SE; McIvor RS; Davidson AS; Hanna M; Traycoff CM; Berebetsky DA; Gonin R; Broxmeyer HE; Cornetta K
    Cancer Gene Ther; 1997; 4(1):26-32. PubMed ID: 9012448
    [TBL] [Abstract][Full Text] [Related]  

  • 10. [In vitro study on the transduction of mutant human dihydrofolate reductase cDNA into human umbilical cord blood CD34+ cells].
    Wu R; Yang Z; Liu J
    Zhonghua Xue Ye Xue Za Zhi; 1999 Mar; 20(3):140-2. PubMed ID: 11601241
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Co-expression of the herpes simplex virus thymidine kinase gene potentiates methotrexate resistance conferred by transfer of a mutated dihydrofolate reductase gene.
    Mineishi S; Nakahara S; Takebe N; Banerjee D; Zhao SC; Bertino JR
    Gene Ther; 1997 Jun; 4(6):570-6. PubMed ID: 9231073
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Retroviral transduction of human dihydropyrimidine dehydrogenase cDNA confers resistance to 5-fluorouracil in murine hematopoietic progenitor cells and human CD34+-enriched peripheral blood progenitor cells.
    Takebe N; Zhao SC; Ural AU; Johnson MR; Banerjee D; Diasio RB; Bertino JR
    Cancer Gene Ther; 2001 Dec; 8(12):966-73. PubMed ID: 11781659
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Drug-resistant dihydrofolate reductases: generation, expression and therapeutic application.
    McIvor RS
    Bone Marrow Transplant; 1996 Dec; 18 Suppl 3():S50-4. PubMed ID: 8971409
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Coexpression of cytidine deaminase and mutant dihydrofolate reductase by a bicistronic retroviral vector confers resistance to cytosine arabinoside and methotrexate.
    Beauséjour CM; Le NL; Létourneau S; Cournoyer D; Momparler RL
    Hum Gene Ther; 1998 Nov; 9(17):2537-44. PubMed ID: 9853520
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Transgenic mice expressing the tyr22 variant of murine DHFR: protection of transgenic marrow transplant recipients from lethal doses of methotrexate.
    James RI; May C; Vagt MD; Studebaker R; McIvor RS
    Exp Hematol; 1997 Nov; 25(12):1286-95. PubMed ID: 9357973
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Methotrexate resistance conferred by transplantation of drug-resistant transgenic marrow cells fractionated bycounterflow elutriation.
    James R; May C; Diers M; Wagner J; McIvor R
    Bone Marrow Transplant; 1999 Oct; 24(8):815-21. PubMed ID: 10516690
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Methotrexate preconditioning allows sufficient engraftment to confer drug resistance in mice transplanted with marrow expressing drug-resistant dihydrofolate reductase activity.
    Belur LR; James RI; May C; Diers MD; Swanson D; Gunther R; McIvor RS
    J Pharmacol Exp Ther; 2005 Aug; 314(2):668-74. PubMed ID: 15857949
    [TBL] [Abstract][Full Text] [Related]  

  • 18. [Protective effect of mutant dihydrofolate reductase gene on human peripheral blood CD34+ cells against methotrexate].
    Wu R; Yang Z; Liu J
    Zhonghua Zhong Liu Za Zhi; 1999 May; 21(3):186-9. PubMed ID: 11776831
    [TBL] [Abstract][Full Text] [Related]  

  • 19. In vivo methotrexate selection of murine hemopoietic cells transduced with a retroviral vector for Gaucher disease.
    Havenga M; Valerio D; Hoogerbrugge P; Es H
    Gene Ther; 1999 Oct; 6(10):1661-9. PubMed ID: 10516714
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Methotrexate accumulates to similar levels in animals transplanted with normal versus drug-resistant transgenic marrow.
    Belur LR; Boelk-Galvan D; Diers MD; McIvor RS; Zimmerman CL
    Cancer Res; 2001 Feb; 61(4):1522-6. PubMed ID: 11245460
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 26.