BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

200 related articles for article (PubMed ID: 11163771)

  • 1. Essential role of the N-terminal autoregulatory sequence in the regulation of phenylalanine hydroxylase.
    Jennings IG; Teh T; Kobe B
    FEBS Lett; 2001 Jan; 488(3):196-200. PubMed ID: 11163771
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Recombinant human phenylalanine hydroxylase: novel regulatory and structural properties.
    Kowlessur D; Citron BA; Kaufman S
    Arch Biochem Biophys; 1996 Sep; 333(1):85-95. PubMed ID: 8806757
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Probing cofactor specificity in phenylalanine hydroxylase by molecular dynamics simulations.
    Teigen K; Martinez A
    J Biomol Struct Dyn; 2003 Jun; 20(6):733-40. PubMed ID: 12744702
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Structural characterization of the N-terminal autoregulatory sequence of phenylalanine hydroxylase.
    Horne J; Jennings IG; Teh T; Gooley PR; Kobe B
    Protein Sci; 2002 Aug; 11(8):2041-7. PubMed ID: 12142458
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Structural comparison of bacterial and human iron-dependent phenylalanine hydroxylases: similar fold, different stability and reaction rates.
    Erlandsen H; Kim JY; Patch MG; Han A; Volner A; Abu-Omar MM; Stevens RC
    J Mol Biol; 2002 Jul; 320(3):645-61. PubMed ID: 12096915
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Activation of phenylalanine hydroxylase induces positive cooperativity toward the natural cofactor.
    Gersting SW; Staudigl M; Truger MS; Messing DD; Danecka MK; Sommerhoff CP; Kemter KF; Muntau AC
    J Biol Chem; 2010 Oct; 285(40):30686-97. PubMed ID: 20667834
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The interplay between genotype, metabolic state and cofactor treatment governs phenylalanine hydroxylase function and drug response.
    Staudigl M; Gersting SW; Danecka MK; Messing DD; Woidy M; Pinkas D; Kemter KF; Blau N; Muntau AC
    Hum Mol Genet; 2011 Jul; 20(13):2628-41. PubMed ID: 21527427
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Structural basis of autoregulation of phenylalanine hydroxylase.
    Kobe B; Jennings IG; House CM; Michell BJ; Goodwill KE; Santarsiero BD; Stevens RC; Cotton RG; Kemp BE
    Nat Struct Biol; 1999 May; 6(5):442-8. PubMed ID: 10331871
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Functional analysis, using in vitro mutagenesis, of amino acids located in the phenylalanine hydroxylase active site.
    Jennings IG; Cotton RG; Kobe B
    Arch Biochem Biophys; 2000 Dec; 384(2):238-44. PubMed ID: 11368310
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Modulation by pterins of the phosphorylation and phenylalanine activation of phenylalanine 4-mono-oxygenase.
    Døskeland AP; Haavik J; Flatmark T; Døskeland SO
    Biochem J; 1987 Mar; 242(3):867-74. PubMed ID: 3036104
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Ligand effects on the limited proteolysis of phenylalanine hydroxylase: evidence for multiple conformational states.
    Phillips RS; Iwaki M; Kaufman S
    Biochem Biophys Res Commun; 1983 Feb; 110(3):919-25. PubMed ID: 6838560
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Mechanisms underlying responsiveness to tetrahydrobiopterin in mild phenylketonuria mutations.
    Pey AL; Pérez B; Desviat LR; Martínez MA; Aguado C; Erlandsen H; Gámez A; Stevens RC; Thórólfsson M; Ugarte M; Martínez A
    Hum Mutat; 2004 Nov; 24(5):388-99. PubMed ID: 15459954
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Expression and characterization of the catalytic domain of human phenylalanine hydroxylase.
    Daubner SC; Hillas PJ; Fitzpatrick PF
    Arch Biochem Biophys; 1997 Dec; 348(2):295-302. PubMed ID: 9434741
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Phenylalanine hydroxylase: function, structure, and regulation.
    Flydal MI; Martinez A
    IUBMB Life; 2013 Apr; 65(4):341-9. PubMed ID: 23457044
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The effect of substrate, dihydrobiopterin, and dopamine on the EPR spectroscopic properties and the midpoint potential of the catalytic iron in recombinant human phenylalanine hydroxylase.
    Hagedoorn PL; Schmidt PP; Andersson KK; Hagen WR; Flatmark T; Martínez A
    J Biol Chem; 2001 Jun; 276(25):22850-6. PubMed ID: 11301319
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Effects of tetrahydrobiopterin and phenylalanine on in vivo human phenylalanine hydroxylase by phenylalanine breath test.
    Okano Y; Takatori K; Kudo S; Sakaguchi T; Asada M; Kajiwara M; Yamano T
    Mol Genet Metab; 2007 Dec; 92(4):308-14. PubMed ID: 17884650
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The activity of wild-type and mutant phenylalanine hydroxylase and its regulation by phenylalanine and tetrahydrobiopterin at physiological and pathological concentrations: an isothermal titration calorimetry study.
    Pey AL; Martinez A
    Mol Genet Metab; 2005 Dec; 86 Suppl 1():S43-53. PubMed ID: 15936235
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Structure of full-length human phenylalanine hydroxylase in complex with tetrahydrobiopterin.
    Flydal MI; Alcorlo-Pagés M; Johannessen FG; Martínez-Caballero S; Skjærven L; Fernandez-Leiro R; Martinez A; Hermoso JA
    Proc Natl Acad Sci U S A; 2019 Jun; 116(23):11229-11234. PubMed ID: 31118288
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A hypothesis on the biochemical mechanism of BH(4)-responsiveness in phenylalanine hydroxylase deficiency.
    Steinfeld R; Kohlschütter A; Ullrich K; Lukacs Z
    Amino Acids; 2003 Jul; 25(1):63-8. PubMed ID: 12836060
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Loss of function in phenylketonuria is caused by impaired molecular motions and conformational instability.
    Gersting SW; Kemter KF; Staudigl M; Messing DD; Danecka MK; Lagler FB; Sommerhoff CP; Roscher AA; Muntau AC
    Am J Hum Genet; 2008 Jul; 83(1):5-17. PubMed ID: 18538294
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.