These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

283 related articles for article (PubMed ID: 11164988)

  • 1. Metabolic activation in drug allergies.
    Park BK; Naisbitt DJ; Gordon SF; Kitteringham NR; Pirmohamed M
    Toxicology; 2001 Feb; 158(1-2):11-23. PubMed ID: 11164988
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Reactive metabolites and their role in drug reactions.
    Naisbitt DJ; Williams DP; Pirmohamed M; Kitteringham NR; Park BK
    Curr Opin Allergy Clin Immunol; 2001 Aug; 1(4):317-25. PubMed ID: 11964707
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Mechanism of idiosyncratic drug reactions: reactive metabolite formation, protein binding and the regulation of the immune system.
    Ju C; Uetrecht JP
    Curr Drug Metab; 2002 Aug; 3(4):367-77. PubMed ID: 12093356
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The role of reactive drug metabolites in immune-mediated adverse drug reactions.
    Hess DA; Rieder MJ
    Ann Pharmacother; 1997 Nov; 31(11):1378-87. PubMed ID: 9391694
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Metabolomics in drug intolerance.
    Andreu I; Mayorga C; Miranda MA
    Curr Drug Metab; 2009 Nov; 10(9):947-55. PubMed ID: 20214587
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Immunological principles of adverse drug reactions: the initiation and propagation of immune responses elicited by drug treatment.
    Naisbitt DJ; Gordon SF; Pirmohamed M; Park BK
    Drug Saf; 2000 Dec; 23(6):483-507. PubMed ID: 11144658
    [TBL] [Abstract][Full Text] [Related]  

  • 7. In vitro analysis of metabolic predisposition to drug hypersensitivity reactions.
    Riley RJ; Leeder JS
    Clin Exp Immunol; 1995 Jan; 99(1):1-6. PubMed ID: 7813099
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Role of bioactivation in drug-induced hypersensitivity reactions.
    Sanderson JP; Naisbitt DJ; Park BK
    AAPS J; 2006 Feb; 8(1):E55-64. PubMed ID: 16584134
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Reactive Metabolites: Current and Emerging Risk and Hazard Assessments.
    Thompson RA; Isin EM; Ogese MO; Mettetal JT; Williams DP
    Chem Res Toxicol; 2016 Apr; 29(4):505-33. PubMed ID: 26735163
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Deciphering the immune pathomechanism of cutaneous drug reactions.
    Pichler WJ
    Allergy; 2002; 57 Suppl 72():34-6. PubMed ID: 12144552
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Role of drug metabolism for breaking tolerance and the localization of drug hypersensitivity.
    Uetrecht J
    Toxicology; 2005 Apr; 209(2):113-8. PubMed ID: 15767022
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Noncovalent interactions of drugs with immune receptors may mediate drug-induced hypersensitivity reactions.
    Gerber BO; Pichler WJ
    AAPS J; 2006 Mar; 8(1):E160-5. PubMed ID: 16584124
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Evaluation of which reactive metabolite, if any, is responsible for a specific idiosyncratic reaction.
    Uetrecht J
    Drug Metab Rev; 2006; 38(4):745-53. PubMed ID: 17145699
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Idiosyncratic toxicity: the role of toxicophores and bioactivation.
    Williams DP; Park BK
    Drug Discov Today; 2003 Nov; 8(22):1044-50. PubMed ID: 14690635
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Reactive metabolites and adverse drug reactions: clinical considerations.
    Knowles SR; Shapiro LE; Shear NH
    Clin Rev Allergy Immunol; 2003 Jun; 24(3):229-38. PubMed ID: 12721394
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Mechanisms of drug toxicity and relevance to pharmaceutical development.
    Guengerich FP
    Drug Metab Pharmacokinet; 2011; 26(1):3-14. PubMed ID: 20978361
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Advances in molecular toxicology-towards understanding idiosyncratic drug toxicity.
    Park BK; Kitteringham NR; Powell H; Pirmohamed M
    Toxicology; 2000 Nov; 153(1-3):39-60. PubMed ID: 11090946
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The roles of drug metabolism in the pathogenesis of T-cell-mediated drug hypersensitivity.
    Lavergne SN; Park BK; Naisbitt DJ
    Curr Opin Allergy Clin Immunol; 2008 Aug; 8(4):299-307. PubMed ID: 18596585
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Is it possible to more accurately predict which drug candidates will cause idiosyncratic drug reactions?
    Uetrecht JP
    Curr Drug Metab; 2000 Sep; 1(2):133-41. PubMed ID: 11465079
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Idiosyncratic drug reactions: possible role of reactive metabolites generated by leukocytes.
    Uetrecht JP
    Pharm Res; 1989 Apr; 6(4):265-73. PubMed ID: 2664753
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.