124 related articles for article (PubMed ID: 11179442)
1. Amino acid residues critical for differential inhibition of CYP2B4, CYP2B5, and CYP2B1 by phenylimidazoles.
Spatzenegger M; Wang Q; He YQ; Wester MR; Johnson EF; Halpert JR
Mol Pharmacol; 2001 Mar; 59(3):475-84. PubMed ID: 11179442
[TBL] [Abstract][Full Text] [Related]
2. Use of Phenoxyaniline Analogues To Generate Biochemical Insights into the Interactio n of Polybrominated Diphenyl Ether with CYP2B Enzymes.
Chen C; Liu J; Halpert JR; Wilderman PR
Biochemistry; 2018 Feb; 57(5):817-826. PubMed ID: 29215266
[TBL] [Abstract][Full Text] [Related]
3. Molecular modelling of CYP2B6, the human CYP2B isoform, by homology with the substrate-bound CYP102 crystal structure: evaluation of CYP2B6 substrate characteristics, the cytochrome b5 binding site and comparisons with CYP2B1 and CYP2B4.
Lewis DF; Lake BG; Dickins M; Eddershaw PJ; Tarbit MH; Goldfarb PS
Xenobiotica; 1999 Apr; 29(4):361-93. PubMed ID: 10375007
[TBL] [Abstract][Full Text] [Related]
4. Identification of key residues in rabbit liver microsomal cytochrome P450 2B4: importance in interactions with NADPH-cytochrome P450 reductase.
Lehnerer M; Schulze J; Achterhold K; Lewis DF; Hlavica P
J Biochem; 2000 Jan; 127(1):163-9. PubMed ID: 10731679
[TBL] [Abstract][Full Text] [Related]
5. Structural requirements for inhibitors of cytochromes P450 2B: assessment of the enzyme interaction with diamondoids.
Hodek P; Bortek-Dohalská L; Sopko B; Sulc M; Smrcek S; Hudecek J; Janků J; Stiborová M
J Enzyme Inhib Med Chem; 2005 Feb; 20(1):25-33. PubMed ID: 15895681
[TBL] [Abstract][Full Text] [Related]
6. Molecular basis for the differences in lidocaine binding and regioselectivity of oxidation by cytochromes P450 2B1 and 2B2.
Hanna IH; Roberts ES; Hollenberg PF
Biochemistry; 1998 Jan; 37(1):311-8. PubMed ID: 9425052
[TBL] [Abstract][Full Text] [Related]
7. Escherichia coli expression and characterization of cytochromes P450 2B11, 2B1, and 2B5.
John GH; Hasler JA; He YA; Halpert JR
Arch Biochem Biophys; 1994 Nov; 314(2):367-75. PubMed ID: 7979377
[TBL] [Abstract][Full Text] [Related]
8. Elucidation of amino acid residues critical for unique activities of rabbit cytochrome P450 2B5 using hybrid enzymes and reciprocal site-directed mutagenesis with rabbit cytochrome P450 2B4.
Szklarz GD; He YQ; Kedzie KM; Halpert JR; Burnett VL
Arch Biochem Biophys; 1996 Mar; 327(2):308-18. PubMed ID: 8619620
[TBL] [Abstract][Full Text] [Related]
9. Quantitative structure-activity relationships (QSARs) for inhibitors and substrates of CYP2B enzymes: importance of compound lipophilicity in explanation of potency differences.
Lewis DF; Ito Y; Lake BG
J Enzyme Inhib Med Chem; 2010 Oct; 25(5):679-84. PubMed ID: 20100069
[TBL] [Abstract][Full Text] [Related]
10. Influence of mutation of the amino-terminal signal anchor sequence of cytochrome P450 2B4 on the enzyme structure and electron transfer processes.
Lehnerer M; Schulze J; Pernecky SJ; Lewis DF; Eulitz M; Hlavica P
J Biochem; 1998 Aug; 124(2):396-403. PubMed ID: 9685732
[TBL] [Abstract][Full Text] [Related]
11. Engineering of cytochrome P450 2B1 specificity. Conversion of an androgen 16 beta-hydroxylase to a 15 alpha-hydroxylase.
Halpert JR; He YA
J Biol Chem; 1993 Feb; 268(6):4453-7. PubMed ID: 8440727
[TBL] [Abstract][Full Text] [Related]
12. Competitive CYP2C9 inhibitors: enzyme inhibition studies, protein homology modeling, and three-dimensional quantitative structure-activity relationship analysis.
Afzelius L; Zamora I; Ridderström M; Andersson TB; Karlén A; Masimirembwa CM
Mol Pharmacol; 2001 Apr; 59(4):909-19. PubMed ID: 11259637
[TBL] [Abstract][Full Text] [Related]
13. 2,2',3,3',6,6'-hexachlorobiphenyl hydroxylation by active site mutants of cytochrome P450 2B1 and 2B11.
Waller SC; He YA; Harlow GR; He YQ; Mash EA; Halpert JR
Chem Res Toxicol; 1999 Aug; 12(8):690-9. PubMed ID: 10458702
[TBL] [Abstract][Full Text] [Related]
14. Comparison of in vitro metabolism of ticlopidine by human cytochrome P450 2B6 and rabbit cytochrome P450 2B4.
Talakad JC; Shah MB; Walker GS; Xiang C; Halpert JR; Dalvie D
Drug Metab Dispos; 2011 Mar; 39(3):539-50. PubMed ID: 21156812
[TBL] [Abstract][Full Text] [Related]
15. Role of residue 480 in substrate specificity of cytochrome P450 2B5 and 2B11.
Liu J; He YA; Halpert JR
Arch Biochem Biophys; 1996 Mar; 327(1):167-73. PubMed ID: 8615687
[TBL] [Abstract][Full Text] [Related]
16. Molecular modelling of mammalian CYP2B isoforms and their interaction with substrates, inhibitors and redox partners.
Lewis DF; Lake BG
Xenobiotica; 1997 May; 27(5):443-78. PubMed ID: 9179987
[TBL] [Abstract][Full Text] [Related]
17. Site-directed mutagenesis of mouse steroid 7 alpha-hydroxylase (cytochrome P-450(7) alpha): role of residue-209 in determining steroid-cytochrome P-450 interaction.
Iwasaki M; Lindberg RL; Juvonen RO; Negishi M
Biochem J; 1993 Apr; 291 ( Pt 2)(Pt 2):569-73. PubMed ID: 8484736
[TBL] [Abstract][Full Text] [Related]
18. Theoretical study of the ligand-CYP2B4 complexes: effect of structure on binding free energies and heme spin state.
Harris DL; Park JY; Gruenke L; Waskell L
Proteins; 2004 Jun; 55(4):895-914. PubMed ID: 15146488
[TBL] [Abstract][Full Text] [Related]
19. Targeting of the highly conserved threonine 302 residue of cytochromes P450 2B family during mechanism-based inactivation by aryl acetylenes.
Zhang H; Lin HL; Kenaan C; Hollenberg PF
Arch Biochem Biophys; 2011 Mar; 507(1):135-43. PubMed ID: 20836985
[TBL] [Abstract][Full Text] [Related]
20. Structural determinants of progesterone hydroxylation by cytochrome P450 2B5: the role of nonsubstrate recognition site residues.
He YQ; Harlow GR; Szklarz GD; Halpert JR
Arch Biochem Biophys; 1998 Feb; 350(2):333-9. PubMed ID: 9473309
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]