177 related articles for article (PubMed ID: 11179981)
1. Inhibitory sequences in the N-terminus of the double-stranded-RNA-dependent protein kinase, PKR, are important for regulating phosphorylation of eukaryotic initiation factor 2alpha (eIF2alpha).
Vattem KM; Staschke KA; Zhu S; Wek RC
Eur J Biochem; 2001 Feb; 268(4):1143-53. PubMed ID: 11179981
[TBL] [Abstract][Full Text] [Related]
2. The double-stranded RNA-activated protein kinase PKR is dispensable for regulation of translation initiation in response to either calcium mobilization from the endoplasmic reticulum or essential amino acid starvation.
Kimball SR; Clemens MJ; Tilleray VJ; Wek RC; Horetsky RL; Jefferson LS
Biochem Biophys Res Commun; 2001 Jan; 280(1):293-300. PubMed ID: 11162513
[TBL] [Abstract][Full Text] [Related]
3. Ribosome targeting of PKR is mediated by two double-stranded RNA-binding domains and facilitates in vivo phosphorylation of eukaryotic initiation factor-2.
Zhu S; Romano PR; Wek RC
J Biol Chem; 1997 May; 272(22):14434-41. PubMed ID: 9162083
[TBL] [Abstract][Full Text] [Related]
4. Homologous regions of the alpha subunit of eukaryotic translational initiation factor 2 (eIF2alpha) and the vaccinia virus K3L gene product interact with the same domain within the dsRNA-activated protein kinase (PKR).
Sharp TV; Witzel JE; Jagus R
Eur J Biochem; 1997 Nov; 250(1):85-91. PubMed ID: 9431994
[TBL] [Abstract][Full Text] [Related]
5. Mutations in the double-stranded RNA-activated protein kinase insert region that uncouple catalysis from eIF2alpha binding.
Cai R; Williams BR
J Biol Chem; 1998 May; 273(18):11274-80. PubMed ID: 9556619
[TBL] [Abstract][Full Text] [Related]
6. Phosphorylation of eukaryotic translation initiation factor 2 mediates apoptosis in response to activation of the double-stranded RNA-dependent protein kinase.
Srivastava SP; Kumar KU; Kaufman RJ
J Biol Chem; 1998 Jan; 273(4):2416-23. PubMed ID: 9442091
[TBL] [Abstract][Full Text] [Related]
7. Induction of apoptosis by double-stranded-RNA-dependent protein kinase (PKR) involves the alpha subunit of eukaryotic translation initiation factor 2 and NF-kappaB.
Gil J; Alcamí J; Esteban M
Mol Cell Biol; 1999 Jul; 19(7):4653-63. PubMed ID: 10373514
[TBL] [Abstract][Full Text] [Related]
8. Inhibition of the double-stranded RNA-dependent protein kinase PKR by mammalian ribosomes.
Raine DA; Jeffrey IW; Clemens MJ
FEBS Lett; 1998 Oct; 436(3):343-8. PubMed ID: 9801145
[TBL] [Abstract][Full Text] [Related]
9. Double-stranded (ds) RNA binding and not dimerization correlates with the activation of the dsRNA-dependent protein kinase (PKR).
Wu S; Kaufman RJ
J Biol Chem; 1996 Jan; 271(3):1756-63. PubMed ID: 8576179
[TBL] [Abstract][Full Text] [Related]
10. Double-stranded RNA-activated protein kinase (PKR) is negatively regulated by 60S ribosomal subunit protein L18.
Kumar KU; Srivastava SP; Kaufman RJ
Mol Cell Biol; 1999 Feb; 19(2):1116-25. PubMed ID: 9891046
[TBL] [Abstract][Full Text] [Related]
11. The interferon-induced double-stranded RNA-activated protein kinase PKR will phosphorylate serine, threonine, or tyrosine at residue 51 in eukaryotic initiation factor 2alpha.
Lu J; O'Hara EB; Trieselmann BA; Romano PR; Dever TE
J Biol Chem; 1999 Nov; 274(45):32198-203. PubMed ID: 10542257
[TBL] [Abstract][Full Text] [Related]
12. The herpes simplex virus US11 protein effectively compensates for the gamma1(34.5) gene if present before activation of protein kinase R by precluding its phosphorylation and that of the alpha subunit of eukaryotic translation initiation factor 2.
Cassady KA; Gross M; Roizman B
J Virol; 1998 Nov; 72(11):8620-6. PubMed ID: 9765401
[TBL] [Abstract][Full Text] [Related]
13. Protein kinase R is responsible for the phosphorylation of eIF2alpha in rotavirus infection.
Rojas M; Arias CF; López S
J Virol; 2010 Oct; 84(20):10457-66. PubMed ID: 20631127
[TBL] [Abstract][Full Text] [Related]
14. Role of double-stranded RNA-dependent protein kinase in mediating hypersensitivity of Fanconi anemia complementation group C cells to interferon gamma, tumor necrosis factor-alpha, and double-stranded RNA.
Pang Q; Keeble W; Diaz J; Christianson TA; Fagerlie S; Rathbun K; Faulkner GR; O'Dwyer M; Bagby GC
Blood; 2001 Mar; 97(6):1644-52. PubMed ID: 11238103
[TBL] [Abstract][Full Text] [Related]
15. Identification and requirement of three ribosome binding domains in dsRNA-dependent protein kinase (PKR).
Wu S; Kumar KU; Kaufman RJ
Biochemistry; 1998 Sep; 37(39):13816-26. PubMed ID: 9753471
[TBL] [Abstract][Full Text] [Related]
16. Role of the amino-terminal residues of the interferon-induced protein kinase in its activation by double-stranded RNA and heparin.
Patel RC; Stanton P; Sen GC
J Biol Chem; 1994 Jul; 269(28):18593-8. PubMed ID: 7518438
[TBL] [Abstract][Full Text] [Related]
17. Autophosphorylation in the activation loop is required for full kinase activity in vivo of human and yeast eukaryotic initiation factor 2alpha kinases PKR and GCN2.
Romano PR; Garcia-Barrio MT; Zhang X; Wang Q; Taylor DR; Zhang F; Herring C; Mathews MB; Qin J; Hinnebusch AG
Mol Cell Biol; 1998 Apr; 18(4):2282-97. PubMed ID: 9528799
[TBL] [Abstract][Full Text] [Related]
18. A new double-stranded RNA-binding protein that interacts with PKR.
Coolidge CJ; Patton JG
Nucleic Acids Res; 2000 Mar; 28(6):1407-17. PubMed ID: 10684936
[TBL] [Abstract][Full Text] [Related]
19. In vivo regulation of protein synthesis by phosphorylation of the alpha subunit of wheat eukaryotic initiation factor 2.
Gil J; Esteban M; Roth D
Biochemistry; 2000 Jun; 39(25):7521-30. PubMed ID: 10858301
[TBL] [Abstract][Full Text] [Related]
20. Recombinant vaccinia virus K3L gene product prevents activation of double-stranded RNA-dependent, initiation factor 2 alpha-specific protein kinase.
Carroll K; Elroy-Stein O; Moss B; Jagus R
J Biol Chem; 1993 Jun; 268(17):12837-42. PubMed ID: 8099586
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]