163 related articles for article (PubMed ID: 11186135)
21. Involvement of multiple UDP-glucuronosyltransferase 1A isoforms in glucuronidation of 5-(4'-hydroxyphenyl)-5-phenylhydantoin in human liver microsomes.
Nakajima M; Sakata N; Ohashi N; Kume T; Yokoi T
Drug Metab Dispos; 2002 Nov; 30(11):1250-6. PubMed ID: 12386132
[TBL] [Abstract][Full Text] [Related]
22. Glucuronidation of the second-generation antipsychotic clozapine and its active metabolite N-desmethylclozapine. Potential importance of the UGT1A1 A(TA)₇TAA and UGT1A4 L48V polymorphisms.
Erickson-Ridout KK; Sun D; Lazarus P
Pharmacogenet Genomics; 2012 Aug; 22(8):561-76. PubMed ID: 22565219
[TBL] [Abstract][Full Text] [Related]
23. The UDP-glucuronosyltransferase (UGT) 1A polymorphism c.2042C>G (rs8330) is associated with increased human liver acetaminophen glucuronidation, increased UGT1A exon 5a/5b splice variant mRNA ratio, and decreased risk of unintentional acetaminophen-induced acute liver failure.
Court MH; Freytsis M; Wang X; Peter I; Guillemette C; Hazarika S; Duan SX; Greenblatt DJ; Lee WM;
J Pharmacol Exp Ther; 2013 May; 345(2):297-307. PubMed ID: 23408116
[TBL] [Abstract][Full Text] [Related]
24. Contribution of UDP-glucuronosyltransferase 1A1 and 1A8 to morphine-6-glucuronidation and its kinetic properties.
Ohno S; Kawana K; Nakajin S
Drug Metab Dispos; 2008 Apr; 36(4):688-94. PubMed ID: 18187562
[TBL] [Abstract][Full Text] [Related]
25. Glucuronidation of edaravone by human liver and kidney microsomes: biphasic kinetics and identification of UGT1A9 as the major UDP-glucuronosyltransferase isoform.
Ma L; Sun J; Peng Y; Zhang R; Shao F; Hu X; Zhu J; Wang X; Cheng X; Zhu Y; Wan P; Feng D; Wu H; Wang G
Drug Metab Dispos; 2012 Apr; 40(4):734-41. PubMed ID: 22238289
[TBL] [Abstract][Full Text] [Related]
26. In vitro inhibitory effects of non-steroidal antiinflammatory drugs on UDP-glucuronosyltransferase 1A1-catalysed estradiol 3beta-glucuronidation in human liver microsomes.
Mano Y; Usui T; Kamimura H
Biopharm Drug Dispos; 2005 Jan; 26(1):35-9. PubMed ID: 15593333
[TBL] [Abstract][Full Text] [Related]
27. UGT2B7 promoter variant -840G>A contributes to the variability in hepatic clearance of morphine in patients with sickle cell disease.
Darbari DS; van Schaik RH; Capparelli EV; Rana S; McCarter R; van den Anker J
Am J Hematol; 2008 Mar; 83(3):200-2. PubMed ID: 17724700
[TBL] [Abstract][Full Text] [Related]
28. Correlation between UDP-glucuronosyltransferase genotypes and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone glucuronidation phenotype in human liver microsomes.
Wiener D; Fang JL; Dossett N; Lazarus P
Cancer Res; 2004 Feb; 64(3):1190-6. PubMed ID: 14871856
[TBL] [Abstract][Full Text] [Related]
29. Optimized assays for human UDP-glucuronosyltransferase (UGT) activities: altered alamethicin concentration and utility to screen for UGT inhibitors.
Walsky RL; Bauman JN; Bourcier K; Giddens G; Lapham K; Negahban A; Ryder TF; Obach RS; Hyland R; Goosen TC
Drug Metab Dispos; 2012 May; 40(5):1051-65. PubMed ID: 22357286
[TBL] [Abstract][Full Text] [Related]
30. Differential modulation of UDP-glucuronosyltransferase 1A1 (UGT1A1)-catalyzed estradiol-3-glucuronidation by the addition of UGT1A1 substrates and other compounds to human liver microsomes.
Williams JA; Ring BJ; Cantrell VE; Campanale K; Jones DR; Hall SD; Wrighton SA
Drug Metab Dispos; 2002 Nov; 30(11):1266-73. PubMed ID: 12386134
[TBL] [Abstract][Full Text] [Related]
31. The glucuronidation of morphine by dog liver microsomes: identification of morphine-6-O-glucuronide.
King C; Finley B; Franklin R
Drug Metab Dispos; 2000 Jun; 28(6):661-3. PubMed ID: 10820138
[TBL] [Abstract][Full Text] [Related]
32. Olanzapine metabolism and the significance of UGT1A448V and UGT2B1067Y variants.
Erickson-Ridout KK; Zhu J; Lazarus P
Pharmacogenet Genomics; 2011 Sep; 21(9):539-51. PubMed ID: 21750471
[TBL] [Abstract][Full Text] [Related]
33. The UDP-glucuronosyltransferase 2B7 isozyme is responsible for gemfibrozil glucuronidation in the human liver.
Mano Y; Usui T; Kamimura H
Drug Metab Dispos; 2007 Nov; 35(11):2040-4. PubMed ID: 17670842
[TBL] [Abstract][Full Text] [Related]
34. Product inhibition of UDP-glucuronosyltransferase (UGT) enzymes by UDP obfuscates the inhibitory effects of UGT substrates.
Fujiwara R; Nakajima M; Yamanaka H; Katoh M; Yokoi T
Drug Metab Dispos; 2008 Feb; 36(2):361-7. PubMed ID: 17998297
[TBL] [Abstract][Full Text] [Related]
35. Hetero-oligomer formation of mouse UDP-glucuronosyltransferase (UGT) 2b1 and 1a1 results in the gain of glucuronidation activity towards morphine, an activity which is absent in homo-oligomers of either UGT.
Miyauchi Y; Kurita A; Yamashita R; Takamatsu T; Ikushiro S; Mackenzie PI; Tanaka Y; Ishii Y
Biochem Biophys Res Commun; 2020 Apr; 525(2):348-353. PubMed ID: 32093886
[TBL] [Abstract][Full Text] [Related]
36. Identification of UDP-glucuronosyltransferase isoforms responsible for leonurine glucuronidation in human liver and intestinal microsomes.
Tan B; Cai W; Zhang J; Zhou N; Ma G; Yang P; Zhu Q; Zhu Y
Xenobiotica; 2014 Sep; 44(9):775-84. PubMed ID: 24635759
[TBL] [Abstract][Full Text] [Related]
37. Regioselective glucuronidation of denopamine: marked species differences and identification of human udp-glucuronosyltransferase isoform.
Kaji H; Kume T
Drug Metab Dispos; 2005 Mar; 33(3):403-12. PubMed ID: 15608137
[TBL] [Abstract][Full Text] [Related]
38. Interindividual variability in hepatic drug glucuronidation: studies into the role of age, sex, enzyme inducers, and genetic polymorphism using the human liver bank as a model system.
Court MH
Drug Metab Rev; 2010 Feb; 42(1):209-24. PubMed ID: 19821798
[TBL] [Abstract][Full Text] [Related]
39. Comprehensive Characterization of Mouse UDP-Glucuronosyltransferase (Ugt) Belonging to the Ugt2b Subfamily: Identification of Ugt2b36 as the Predominant Isoform Involved in Morphine Glucuronidation.
Kurita A; Miyauchi Y; Ikushiro S; Mackenzie PI; Yamada H; Ishii Y
J Pharmacol Exp Ther; 2017 May; 361(2):199-208. PubMed ID: 28228532
[TBL] [Abstract][Full Text] [Related]
40. Evaluation of 3'-azido-3'-deoxythymidine, morphine, and codeine as probe substrates for UDP-glucuronosyltransferase 2B7 (UGT2B7) in human liver microsomes: specificity and influence of the UGT2B7*2 polymorphism.
Court MH; Krishnaswamy S; Hao Q; Duan SX; Patten CJ; Von Moltke LL; Greenblatt DJ
Drug Metab Dispos; 2003 Sep; 31(9):1125-33. PubMed ID: 12920168
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]