172 related articles for article (PubMed ID: 11187907)
1. mRNA expression levels of methotrexate resistance-related proteins in childhood leukemia as determined by a standardized competitive template-based RT-PCR method.
Rots MG; Willey JC; Jansen G; Van Zantwijk CH; Noordhuis P; DeMuth JP; Kuiper E; Veerman AJ; Pieters R; Peters GJ
Leukemia; 2000 Dec; 14(12):2166-75. PubMed ID: 11187907
[TBL] [Abstract][Full Text] [Related]
2. Role of folylpolyglutamate synthetase and folylpolyglutamate hydrolase in methotrexate accumulation and polyglutamylation in childhood leukemia.
Rots MG; Pieters R; Peters GJ; Noordhuis P; van Zantwijk CH; Kaspers GJ; Hählen K; Creutzig U; Veerman AJ; Jansen G
Blood; 1999 Mar; 93(5):1677-83. PubMed ID: 10029597
[TBL] [Abstract][Full Text] [Related]
3. Differences in folylpolyglutamate synthetase and dihydrofolate reductase expression in human B-lineage versus T-lineage leukemic lymphoblasts: mechanisms for lineage differences in methotrexate polyglutamylation and cytotoxicity.
Galpin AJ; Schuetz JD; Masson E; Yanishevski Y; Synold TW; Barredo JC; Pui CH; Relling MV; Evans WE
Mol Pharmacol; 1997 Jul; 52(1):155-63. PubMed ID: 9224825
[TBL] [Abstract][Full Text] [Related]
4. Circumvention of methotrexate resistance in childhood leukemia subtypes by rationally designed antifolates.
Rots MG; Pieters R; Peters GJ; van Zantwijk CH; Mauritz R; Noordhuis P; Willey JC; Hählen K; Creutzig U; Janka-Schaub G; Kaspers GJ; Veerman AJ; Jansen G
Blood; 1999 Nov; 94(9):3121-8. PubMed ID: 10556198
[TBL] [Abstract][Full Text] [Related]
5. Differential methotrexate resistance in childhood T- versus common/preB-acute lymphoblastic leukemia can be measured by an in situ thymidylate synthase inhibition assay, but not by the MTT assay.
Rots MG; Pieters R; Kaspers GJ; van Zantwijk CH; Noordhuis P; Mauritz R; Veerman AJ; Jansen G; Peters GJ
Blood; 1999 Feb; 93(3):1067-74. PubMed ID: 9920857
[TBL] [Abstract][Full Text] [Related]
6. Mechanisms of methotrexate resistance in acute leukemia. Decreased transport and polyglutamylation.
Gorlick R; Cole P; Banerjee D; Longo G; Li WW; Hochhauser D; Bertino JR
Adv Exp Med Biol; 1999; 457():543-50. PubMed ID: 10500832
[TBL] [Abstract][Full Text] [Related]
7. A mathematical model of in vivo methotrexate accumulation in acute lymphoblastic leukemia.
Panetta JC; Yanishevski Y; Pui CH; Sandlund JT; Rubnitz J; Rivera GK; Ribeiro R; Evans WE; Relling MV
Cancer Chemother Pharmacol; 2002 Nov; 50(5):419-28. PubMed ID: 12439601
[TBL] [Abstract][Full Text] [Related]
8. A possible role for methotrexate in the treatment of childhood acute myeloid leukaemia, in particular for acute monocytic leukaemia.
Rots MG; Pieters R; Jansen G; Kaspers GJ; Van Zantwijk CH; Noordhuis P; Voorn DA; Van Wering ER; Creutzig U; Veerman AJ; Peters GJ
Eur J Cancer; 2001 Mar; 37(4):492-8. PubMed ID: 11267859
[TBL] [Abstract][Full Text] [Related]
9. Loss of folylpoly-gamma-glutamate synthetase activity is a dominant mechanism of resistance to polyglutamylation-dependent novel antifolates in multiple human leukemia sublines.
Liani E; Rothem L; Bunni MA; Smith CA; Jansen G; Assaraf YG
Int J Cancer; 2003 Feb; 103(5):587-99. PubMed ID: 12494465
[TBL] [Abstract][Full Text] [Related]
10. The influence of drug-exposure conditions on the development of resistance to methotrexate or ZD1694 in cultured human leukaemia cells.
Takemura Y; Kobayashi H; Gibson W; Kimbell R; Miyachi H; Jackman AL
Int J Cancer; 1996 Mar; 66(1):29-36. PubMed ID: 8608962
[TBL] [Abstract][Full Text] [Related]
11. Methotrexate resistance in relation to treatment outcome in childhood acute lymphoblastic leukemia.
Wojtuszkiewicz A; Peters GJ; van Woerden NL; Dubbelman B; Escherich G; Schmiegelow K; Sonneveld E; Pieters R; van de Ven PM; Jansen G; Assaraf YG; Kaspers GJ; Cloos J
J Hematol Oncol; 2015 May; 8():61. PubMed ID: 26022503
[TBL] [Abstract][Full Text] [Related]
12. Differences in constitutive and post-methotrexate folylpolyglutamate synthetase activity in B-lineage and T-lineage leukemia.
Barredo JC; Synold TW; Laver J; Relling MV; Pui CH; Priest DG; Evans WE
Blood; 1994 Jul; 84(2):564-9. PubMed ID: 7517720
[TBL] [Abstract][Full Text] [Related]
13. [Primary study on establishment of namalwa 12/MTX resistant cell strain and its mechanism].
Chen J; Gu LJ; Ying DM; Shen M; Wu HJ
Ai Zheng; 2002 Dec; 21(12):1335-40. PubMed ID: 12520743
[TBL] [Abstract][Full Text] [Related]
14. mRNA expression levels of E2F transcription factors correlate with dihydrofolate reductase, reduced folate carrier, and thymidylate synthase mRNA expression in osteosarcoma.
Sowers R; Toguchida J; Qin J; Meyers PA; Healey JH; Huvos A; Banerjee D; Bertino JR; Gorlick R
Mol Cancer Ther; 2003 Jun; 2(6):535-41. PubMed ID: 12813132
[TBL] [Abstract][Full Text] [Related]
15. Cellular and molecular mechanisms of resistance to antifolate drugs: new analogues and approaches to overcome the resistance.
Takemura Y; Kobayashi H; Miyachi H
Int J Hematol; 1997 Dec; 66(4):459-77. PubMed ID: 9479873
[TBL] [Abstract][Full Text] [Related]
16. Ex vivo activity of methotrexate versus novel antifolate inhibitors of dihydrofolate reductase and thymidylate synthase against childhood leukemia cells.
Mauritz R; Bekkenk MW; Rots MG; Pieters R; Mini E; van Zantwijk CH; Veerman AJ; Peters GJ; Jansen G
Clin Cancer Res; 1998 Oct; 4(10):2399-410. PubMed ID: 9796971
[TBL] [Abstract][Full Text] [Related]
17. Histone deacetylase inhibitors induce FPGS mRNA expression and intracellular accumulation of long-chain methotrexate polyglutamates in childhood acute lymphoblastic leukemia: implications for combination therapy.
Leclerc GJ; Mou C; Leclerc GM; Mian AM; Barredo JC
Leukemia; 2010 Mar; 24(3):552-62. PubMed ID: 20072153
[TBL] [Abstract][Full Text] [Related]
18. Reduced folate carrier and dihydrofolate reductase expression in acute lymphocytic leukemia may predict outcome: a Children's Cancer Group Study.
Levy AS; Sather HN; Steinherz PG; Sowers R; La M; Moscow JA; Gaynon PS; Uckun FM; Bertino JR; Gorlick R;
J Pediatr Hematol Oncol; 2003 Sep; 25(9):688-95. PubMed ID: 12972803
[TBL] [Abstract][Full Text] [Related]
19. Multiple mechanisms of resistance to methotrexate and novel antifolates in human CCRF-CEM leukemia cells and their implications for folate homeostasis.
Mauritz R; Peters GJ; Priest DG; Assaraf YG; Drori S; Kathmann I; Noordhuis P; Bunni MA; Rosowsky A; Schornagel JH; Pinedo HM; Jansen G
Biochem Pharmacol; 2002 Jan; 63(2):105-15. PubMed ID: 11841783
[TBL] [Abstract][Full Text] [Related]
20. Gene expression profiling of leukemia T-cells resistant to methotrexate and 7-hydroxymethotrexate reveals alterations that preserve intracellular levels of folate and nucleotide biosynthesis.
Fotoohi AK; Assaraf YG; Moshfegh A; Hashemi J; Jansen G; Peters GJ; Larsson C; Albertioni F
Biochem Pharmacol; 2009 Apr; 77(8):1410-7. PubMed ID: 19426680
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
