BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

82 related articles for article (PubMed ID: 11193157)

  • 1. Overexpression of presenilin-2 enhances apoptotic death of cultured cortical neurons.
    Araki W; Yuasa K; Takeda S; Shirotani K; Takahashi K; Tabira T
    Ann N Y Acad Sci; 2000; 920():241-4. PubMed ID: 11193157
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Pro-apoptotic effect of presenilin 2 (PS2) overexpression is associated with down-regulation of Bcl-2 in cultured neurons.
    Araki W; Yuasa K; Takeda S; Takeda K; Shirotani K; Takahashi K; Tabira T
    J Neurochem; 2001 Dec; 79(6):1161-8. PubMed ID: 11752057
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Overexpression in neurons of human presenilin-1 or a presenilin-1 familial Alzheimer disease mutant does not enhance apoptosis.
    Bursztajn S; DeSouza R; McPhie DL; Berman SA; Shioi J; Robakis NK; Neve RL
    J Neurosci; 1998 Dec; 18(23):9790-9. PubMed ID: 9822738
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Overexpression of wild-type presenilin 2 or its familial Alzheimer's disease-associated mutant does not induce or increase susceptibility to apoptosis in different cell lines.
    Gamliel A; Teicher C; Hartmann T; Beyreuther K; Stein R
    Neuroscience; 2003; 117(1):19-28. PubMed ID: 12605888
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Inhibition of cyclooxygenase as potential novel therapeutic strategy in N141I presenilin-2 familial Alzheimer's disease.
    Qin W; Peng Y; Ksiezak-Reding H; Ho L; Stetka B; Lovati E; Pasinetti GM
    Mol Psychiatry; 2006 Feb; 11(2):172-81. PubMed ID: 16331303
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Wild-type and mutated presenilins 2 trigger p53-dependent apoptosis and down-regulate presenilin 1 expression in HEK293 human cells and in murine neurons.
    Alves da Costa C; Paitel E; Mattson MP; Amson R; Telerman A; Ancolio K; Checler F
    Proc Natl Acad Sci U S A; 2002 Mar; 99(6):4043-8. PubMed ID: 11904448
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Contrasting role of presenilin-1 and presenilin-2 in neuronal differentiation in vitro.
    Hong CS; Caromile L; Nomata Y; Mori H; Bredesen DE; Koo EH
    J Neurosci; 1999 Jan; 19(2):637-43. PubMed ID: 9880584
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Participation of presenilin 2 in apoptosis: enhanced basal activity conferred by an Alzheimer mutation.
    Wolozin B; Iwasaki K; Vito P; Ganjei JK; LacanĂ  E; Sunderland T; Zhao B; Kusiak JW; Wasco W; D'Adamio L
    Science; 1996 Dec; 274(5293):1710-3. PubMed ID: 8939861
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Ryanodine receptor-mediated interference of neuronal cell differentiation by presenilin 2 mutation.
    Lee SM; Lee JW; Song YS; Hwang DY; Kim YK; Nam SY; Kim DJ; Yun YW; Yoon DY; Hong JT
    J Neurosci Res; 2005 Nov; 82(4):542-50. PubMed ID: 16240390
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Presenilin overexpression arrests cells in the G1 phase of the cell cycle. Arrest potentiated by the Alzheimer's disease PS2(N141I)mutant.
    Janicki SM; Monteiro MJ
    Am J Pathol; 1999 Jul; 155(1):135-44. PubMed ID: 10393846
    [TBL] [Abstract][Full Text] [Related]  

  • 11. C-terminal maturation fragments of presenilin 1 and 2 control secretion of APP alpha and A beta by human cells and are degraded by proteasome.
    da Costa CA; Ancolio K; Checler F
    Mol Med; 1999 Mar; 5(3):160-8. PubMed ID: 10404513
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Increased expression of presenilin 2 inhibits protein synthesis.
    Gamliel A; Teicher C; Michaelson DM; Pradier L; Hartmann T; Beyreuther K; Stein R
    Mol Cell Neurosci; 2002 Jan; 19(1):111-24. PubMed ID: 11817902
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Neurotoxic mechanisms by Alzheimer's disease-linked N141I mutant presenilin 2.
    Hashimoto Y; Niikura T; Ito Y; Kita Y; Terashita K; Nishimoto I
    J Pharmacol Exp Ther; 2002 Mar; 300(3):736-45. PubMed ID: 11861776
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Requirement of the familial Alzheimer's disease gene PS2 for apoptosis. Opposing effect of ALG-3.
    Vito P; Wolozin B; Ganjei JK; Iwasaki K; LacanĂ  E; D'Adamio L
    J Biol Chem; 1996 Dec; 271(49):31025-8. PubMed ID: 8940094
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Presenilin-1 protects against neuronal apoptosis caused by its interacting protein PAG.
    Zhou Y; Zhang W; Easton R; Ray JW; Lampe P; Jiang Z; Brunkan AL; Goate A; Johnson EM; Wu JY
    Neurobiol Dis; 2002 Mar; 9(2):126-38. PubMed ID: 11895366
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Sensitization of differentiated PC12 cells to apoptosis by presenilin-2 is mediated by p38.
    Sun J; Li M; Han J; Gu J
    Biochem Biophys Res Commun; 2001 Sep; 287(2):536-41. PubMed ID: 11554762
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Neurons overexpressing mutant presenilin-1 are more sensitive to apoptosis induced by endoplasmic reticulum-Golgi stress.
    Terro F; Czech C; Esclaire F; Elyaman W; Yardin C; Baclet MC; Touchet N; Tremp G; Pradier L; Hugon J
    J Neurosci Res; 2002 Aug; 69(4):530-9. PubMed ID: 12210846
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Characterization of human presenilin 1 transgenic rats: increased sensitivity to apoptosis in primary neuronal cultures.
    Czech C; Lesort M; Tremp G; Terro F; Blanchard V; Schombert B; Carpentier N; Dreisler S; Bonici B; Takashima A; Moussaoui S; Hugon J; Pradier L
    Neuroscience; 1998 Nov; 87(2):325-36. PubMed ID: 9740395
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Presenilin mutations linked to familial Alzheimer's disease reduce endoplasmic reticulum and Golgi apparatus calcium levels.
    Zatti G; Burgo A; Giacomello M; Barbiero L; Ghidoni R; Sinigaglia G; Florean C; Bagnoli S; Binetti G; Sorbi S; Pizzo P; Fasolato C
    Cell Calcium; 2006 Jun; 39(6):539-50. PubMed ID: 16620965
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Alzheimer's disease-linked mutation of presenilin 2 (N141I-PS2) drastically lowers APPalpha secretion: control by the proteasome.
    Marambaud P; Alves da Costa C; Ancolio K; Checler F
    Biochem Biophys Res Commun; 1998 Nov; 252(1):134-8. PubMed ID: 9813158
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 5.