BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

202 related articles for article (PubMed ID: 11196171)

  • 1. Transforming growth factor-beta-induced growth inhibition in a Smad4 mutant colon adenoma cell line.
    Fink SP; Swinler SE; Lutterbaugh JD; Massagué J; Thiagalingam S; Kinzler KW; Vogelstein B; Willson JK; Markowitz S
    Cancer Res; 2001 Jan; 61(1):256-60. PubMed ID: 11196171
    [TBL] [Abstract][Full Text] [Related]  

  • 2. TGF-beta-induced nuclear localization of Smad2 and Smad3 in Smad4 null cancer cell lines.
    Fink SP; Mikkola D; Willson JK; Markowitz S
    Oncogene; 2003 Mar; 22(9):1317-23. PubMed ID: 12618756
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Tumor-derived C-terminal mutations of Smad4 with decreased DNA binding activity and enhanced intramolecular interaction.
    Kuang C; Chen Y
    Oncogene; 2004 Feb; 23(5):1021-9. PubMed ID: 14647410
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Expression of Smad4 in the FaDu cell line partially restores TGF-beta growth inhibition but is not sufficient to regulate fibronectin expression or suppress tumorigenicity.
    Hummer BT; Bartlett C; Henry E; Weissman BE
    J Cell Physiol; 2003 Mar; 194(3):289-302. PubMed ID: 12548549
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Smad4-independent regulation of p21/WAF1 by transforming growth factor-beta.
    Ijichi H; Otsuka M; Tateishi K; Ikenoue T; Kawakami T; Kanai F; Arakawa Y; Seki N; Shimizu K; Miyazono K; Kawabe T; Omata M
    Oncogene; 2004 Feb; 23(5):1043-51. PubMed ID: 14762439
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Mutations of the Smad4 gene in acute myelogeneous leukemia and their functional implications in leukemogenesis.
    Imai Y; Kurokawa M; Izutsu K; Hangaishi A; Maki K; Ogawa S; Chiba S; Mitani K; Hirai H
    Oncogene; 2001 Jan; 20(1):88-96. PubMed ID: 11244507
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Smad4 dependency defines two classes of transforming growth factor {beta} (TGF-{beta}) target genes and distinguishes TGF-{beta}-induced epithelial-mesenchymal transition from its antiproliferative and migratory responses.
    Levy L; Hill CS
    Mol Cell Biol; 2005 Sep; 25(18):8108-25. PubMed ID: 16135802
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Suppression of tumorigenesis and induction of p15(ink4b) by Smad4/DPC4 in human pancreatic cancer cells.
    Peng B; Fleming JB; Breslin T; Grau AM; Fojioka S; Abbruzzese JL; Evans DB; Ayers D; Wathen K; Wu T; Robertson KD; Chiao PJ
    Clin Cancer Res; 2002 Nov; 8(11):3628-38. PubMed ID: 12429655
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Smad3 has a critical role in TGF-beta-mediated growth inhibition and apoptosis in colonic epithelial cells.
    Mithani SK; Balch GC; Shiou SR; Whitehead RH; Datta PK; Beauchamp RD
    J Surg Res; 2004 Apr; 117(2):296-305. PubMed ID: 15047135
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Smad7 induces tumorigenicity by blocking TGF-beta-induced growth inhibition and apoptosis.
    Halder SK; Beauchamp RD; Datta PK
    Exp Cell Res; 2005 Jul; 307(1):231-46. PubMed ID: 15922743
    [TBL] [Abstract][Full Text] [Related]  

  • 11. DPC4 (SMAD4) mediates transforming growth factor-beta1 (TGF-beta1) induced growth inhibition and transcriptional response in breast tumour cells.
    de Winter JP; Roelen BA; ten Dijke P; van der Burg B; van den Eijnden-van Raaij AJ
    Oncogene; 1997 Apr; 14(16):1891-9. PubMed ID: 9150356
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Functional consequences of tumorigenic missense mutations in the amino-terminal domain of Smad4.
    Morén A; Itoh S; Moustakas A; Dijke P; Heldin CH
    Oncogene; 2000 Sep; 19(38):4396-404. PubMed ID: 10980615
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Targeting endogenous transforming growth factor beta receptor signaling in SMAD4-deficient human pancreatic carcinoma cells inhibits their invasive phenotype1.
    Subramanian G; Schwarz RE; Higgins L; McEnroe G; Chakravarty S; Dugar S; Reiss M
    Cancer Res; 2004 Aug; 64(15):5200-11. PubMed ID: 15289325
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Distortion of autocrine transforming growth factor beta signal accelerates malignant potential by enhancing cell growth as well as PAI-1 and VEGF production in human hepatocellular carcinoma cells.
    Sugano Y; Matsuzaki K; Tahashi Y; Furukawa F; Mori S; Yamagata H; Yoshida K; Matsushita M; Nishizawa M; Fujisawa J; Inoue K
    Oncogene; 2003 Apr; 22(15):2309-21. PubMed ID: 12700666
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Overexpression of the tumor suppressor gene Smad4/DPC4 induces p21waf1 expression and growth inhibition in human carcinoma cells.
    Hunt KK; Fleming JB; Abramian A; Zhang L; Evans DB; Chiao PJ
    Cancer Res; 1998 Dec; 58(24):5656-61. PubMed ID: 9865717
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A novel dominant negative Smad2 mutation in a TGFbeta resistant human carcinoma cell line.
    Tsang KJ; Tsang D; Brown TN; Crowe DL
    Anticancer Res; 2002; 22(1A):13-9. PubMed ID: 12017275
    [TBL] [Abstract][Full Text] [Related]  

  • 17. IGF-binding proteins mediate TGF-beta 1-induced apoptosis in bovine mammary epithelial BME-UV1 cells.
    Gajewska M; Motyl T
    Comp Biochem Physiol C Toxicol Pharmacol; 2004 Oct; 139(1-3):65-75. PubMed ID: 15556067
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Smad4 silencing in pancreatic cancer cell lines using stable RNA interference and gene expression profiles induced by transforming growth factor-beta.
    Jazag A; Ijichi H; Kanai F; Imamura T; Guleng B; Ohta M; Imamura J; Tanaka Y; Tateishi K; Ikenoue T; Kawakami T; Arakawa Y; Miyagishi M; Taira K; Kawabe T; Omata M
    Oncogene; 2005 Jan; 24(4):662-71. PubMed ID: 15592526
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Kaposi's sarcoma-associated herpesvirus viral IFN regulatory factor 1 inhibits transforming growth factor-beta signaling.
    Seo T; Park J; Choe J
    Cancer Res; 2005 Mar; 65(5):1738-47. PubMed ID: 15753369
    [TBL] [Abstract][Full Text] [Related]  

  • 20. A role for human MUC4 mucin gene, the ErbB2 ligand, as a target of TGF-beta in pancreatic carcinogenesis.
    Jonckheere N; Perrais M; Mariette C; Batra SK; Aubert JP; Pigny P; Van Seuningen I
    Oncogene; 2004 Jul; 23(34):5729-38. PubMed ID: 15184872
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.