BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

257 related articles for article (PubMed ID: 11200500)

  • 1. Role of DNA minor groove alkylation and DNA cross-linking in the cytotoxicity of polybenzamide mustards.
    Turner PR; Denny WA; Ferguson LR
    Anticancer Drug Des; 2000 Aug; 15(4):245-53. PubMed ID: 11200500
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Sequence selectivity, cross-linking efficiency and cytotoxicity of DNA-targeted 4-anilinoquinoline aniline mustards.
    McClean S; Costelloe C; Denny WA; Searcey M; Wakelin LP
    Anticancer Drug Des; 1999 Jun; 14(3):187-204. PubMed ID: 10500495
    [TBL] [Abstract][Full Text] [Related]  

  • 3. DNA minor groove targeted alkylating agents based on bisbenzimidazole carriers: synthesis, cytotoxicity and sequence-specificity of DNA alkylation.
    Smaill JB; Fan JY; Denny WA
    Anticancer Drug Des; 1998 Dec; 13(8):857-80. PubMed ID: 10335264
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Design, synthesis, and biological evaluation of DNA sequence and minor groove selective alkylating agents.
    Lee M; Rhodes AL; Wyatt MD; Forrow S; Hartley JA
    Anticancer Drug Des; 1993 Jun; 8(3):173-92. PubMed ID: 8517912
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Structure of the d(CGCGAATTCGCG)2 complex of the minor groove binding alkylating agent alkamin studied by mass spectrometry.
    Majid AM; Smythe G; Denny WA; Wakelin LP
    Mol Pharmacol; 2007 Apr; 71(4):1165-78. PubMed ID: 17251328
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Mass spectrometry studies of the binding of the minor groove-directed alkylating agent alkamin to AT-tract oligonucleotides.
    Abdul Majid AM; Smythe G; Denny WA; Wakelin LP
    Chem Res Toxicol; 2009 Jan; 22(1):146-57. PubMed ID: 19113942
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Anomalous cross-linking by mechlorethamine of DNA duplexes containing C-C mismatch pairs.
    Romero RM; Mitas M; Haworth IS
    Biochemistry; 1999 Mar; 38(12):3641-8. PubMed ID: 10090751
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Polybenzamide mustards: structure-activity relationships for DNA sequence-specific alkylation.
    Turner PR; Ferguson LR; Denny WA
    Anticancer Drug Des; 1999 Feb; 14(1):61-70. PubMed ID: 10363028
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Chlorambucil-adducts in DNA analyzed at the oligonucleotide level using HPLC-ESI MS.
    Mohamed D; Mowaka S; Thomale J; Linscheid MW
    Chem Res Toxicol; 2009 Aug; 22(8):1435-46. PubMed ID: 19621941
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Reactions of nitrogen mustards with DNA.
    Hemminki K; Kallama S
    IARC Sci Publ; 1986; (78):55-70. PubMed ID: 3583398
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The role of base excision repair in the repair of DNA adducts formed by a series of nitrogen mustard-containing analogues of distamycin of increasing binding site size.
    Brooks N; McHugh PJ; Lee M; Hartley JA
    Anticancer Drug Des; 1999 Feb; 14(1):11-8. PubMed ID: 10363024
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Structure-activity relationship of a series of nitrogen mustard- and pyrrole-containing minor groove-binding agents related to distamycin.
    Wyatt MD; Garbiras BJ; Haskell MK; Lee M; Souhami RL; Hartley JA
    Anticancer Drug Des; 1994 Dec; 9(6):511-25. PubMed ID: 7880376
    [TBL] [Abstract][Full Text] [Related]  

  • 13. DNA-Directed alkylating agents. 7. Synthesis, DNA interaction, and antitumor activity of bis(hydroxymethyl)- and bis(carbamate)-substituted pyrrolizines and imidazoles.
    Atwell GJ; Fan JY; Tan K; Denny WA
    J Med Chem; 1998 Nov; 41(24):4744-54. PubMed ID: 9822545
    [TBL] [Abstract][Full Text] [Related]  

  • 14. RecA-catalyzed, sequence-specific alkylation of DNA by cross-linking oligonucleotides. Effects of length and nonhomologous base substitutions.
    Podyminogin MA; Meyer RB; Gamper HB
    Biochemistry; 1996 Jun; 35(22):7267-74. PubMed ID: 8679556
    [TBL] [Abstract][Full Text] [Related]  

  • 15. SJG-136 (NSC 694501), a novel rationally designed DNA minor groove interstrand cross-linking agent with potent and broad spectrum antitumor activity: part 1: cellular pharmacology, in vitro and initial in vivo antitumor activity.
    Hartley JA; Spanswick VJ; Brooks N; Clingen PH; McHugh PJ; Hochhauser D; Pedley RB; Kelland LR; Alley MC; Schultz R; Hollingshead MG; Schweikart KM; Tomaszewski JE; Sausville EA; Gregson SJ; Howard PW; Thurston DE
    Cancer Res; 2004 Sep; 64(18):6693-9. PubMed ID: 15374986
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Mono- and dysfunctional nitrogen mustard analogues of the DNA minor groove binder pibenzimol. Synthesis, cytotoxicity and interaction with DNA.
    Smaill JB; Fan JY; Papa PV; O'Connor CJ; Denny WA
    Anticancer Drug Des; 1998 Apr; 13(3):221-42. PubMed ID: 9595035
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Adenine-containing DNA-DNA cross-links of antitumor nitrogen mustards.
    Balcome S; Park S; Quirk Dorr DR; Hafner L; Phillips L; Tretyakova N
    Chem Res Toxicol; 2004 Jul; 17(7):950-62. PubMed ID: 15257621
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Reaction of N-(2-chloroethyl)-N-nitrosoureas with DNA: effect of buffers on DNA adduction, cross-linking, and cytotoxicity.
    Chen FX; Bodell WJ; Liang G; Gold B
    Chem Res Toxicol; 1996; 9(1):208-14. PubMed ID: 8924592
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Binding of polybenzamides to DNA: studies by DNase I and chlorambucil interference footprinting and comparison with Hoechst 33258.
    Turner PR; Ferguson LR; Denny WA
    Anticancer Drug Des; 1998 Dec; 13(8):941-54. PubMed ID: 10335268
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Mutations induced by some DNA minor groove binding alkylators in AS52 Chinese hamster cells.
    Wu XC; Marcinkowski K; Turner PM; Ferguson LR
    Mutat Res; 2000 Mar; 448(1):35-45. PubMed ID: 10751621
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.