BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

257 related articles for article (PubMed ID: 11209755)

  • 1. Crystal structure of the caspase activator human granzyme B, a proteinase highly specific for an Asp-P1 residue.
    Estébanez-Perpiña E; Fuentes-Prior P; Belorgey D; Braun M; Kiefersauer R; Maskos K; Huber R; Rubin H; Bode W
    Biol Chem; 2000 Dec; 381(12):1203-14. PubMed ID: 11209755
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The structure of the pro-apoptotic protease granzyme B reveals the molecular determinants of its specificity.
    Waugh SM; Harris JL; Fletterick R; Craik CS
    Nat Struct Biol; 2000 Sep; 7(9):762-5. PubMed ID: 10966646
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The three-dimensional structure of human granzyme B compared to caspase-3, key mediators of cell death with cleavage specificity for aspartic acid in P1.
    Rotonda J; Garcia-Calvo M; Bull HG; Geissler WM; McKeever BM; Willoughby CA; Thornberry NA; Becker JW
    Chem Biol; 2001 Apr; 8(4):357-68. PubMed ID: 11325591
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Crystal structure of the apoptosis-inducing human granzyme A dimer.
    Hink-Schauer C; Estébanez-Perpiñá E; Kurschus FC; Bode W; Jenne DE
    Nat Struct Biol; 2003 Jul; 10(7):535-40. PubMed ID: 12819770
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A novel substrate-binding pocket interaction restricts the specificity of the human NK cell-specific serine protease, Met-ase-1.
    Smyth MJ; O'Connor MD; Trapani JA; Kershaw MH; Brinkworth RI
    J Immunol; 1996 Jun; 156(11):4174-81. PubMed ID: 8666785
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Crystal structure of recombinant human tissue kallikrein at 2.0 A resolution.
    Katz BA; Liu B; Barnes M; Springman EB
    Protein Sci; 1998 Apr; 7(4):875-85. PubMed ID: 9568894
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The 2.2 A crystal structure of human chymase in complex with succinyl-Ala-Ala-Pro-Phe-chloromethylketone: structural explanation for its dipeptidyl carboxypeptidase specificity.
    Pereira PJ; Wang ZM; Rubin H; Huber R; Bode W; Schechter NM; Strobl S
    J Mol Biol; 1999 Feb; 286(1):163-73. PubMed ID: 9931257
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The oligomeric structure of human granzyme A is a determinant of its extended substrate specificity.
    Bell JK; Goetz DH; Mahrus S; Harris JL; Fletterick RJ; Craik CS
    Nat Struct Biol; 2003 Jul; 10(7):527-34. PubMed ID: 12819769
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Binding of amino acid side-chains to S1 cavities of serine proteinases.
    Lu W; Apostol I; Qasim MA; Warne N; Wynn R; Zhang WL; Anderson S; Chiang YW; Ogin E; Rothberg I; Ryan K; Laskowski M
    J Mol Biol; 1997 Feb; 266(2):441-61. PubMed ID: 9047374
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The 2.3 A crystal structure of the catalytic domain of recombinant two-chain human tissue-type plasminogen activator.
    Lamba D; Bauer M; Huber R; Fischer S; Rudolph R; Kohnert U; Bode W
    J Mol Biol; 1996 Apr; 258(1):117-35. PubMed ID: 8613982
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Human granzyme B degrades aggrecan proteoglycan in matrix synthesized by chondrocytes.
    Froelich CJ; Zhang X; Turbov J; Hudig D; Winkler U; Hanna WL
    J Immunol; 1993 Dec; 151(12):7161-71. PubMed ID: 8258716
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Nuclear translocation of granzyme B in target cell apoptosis.
    Pinkoski MJ; Heibein JA; Barry M; Bleackley RC
    Cell Death Differ; 2000 Jan; 7(1):17-24. PubMed ID: 10713717
    [TBL] [Abstract][Full Text] [Related]  

  • 13. P-4 and RNKP-7, new granzyme-like serine proteases expressed in activated rat lymphocytes.
    Ewoldt GR; Smyth MJ; Darcy PK; Harris JL; Craik CS; Horowitz B; Woodard SL; Powers JC; Hudig D
    J Immunol; 1997 May; 158(10):4574-83. PubMed ID: 9144469
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Identification and characterization of murine caspase-14, a new member of the caspase family.
    Ahmad M; Srinivasula SM; Hegde R; Mukattash R; Fernandes-Alnemri T; Alnemri ES
    Cancer Res; 1998 Nov; 58(22):5201-5. PubMed ID: 9823333
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Identification of {alpha}-tubulin as a granzyme B substrate during CTL-mediated apoptosis.
    Goping IS; Sawchuk T; Underhill DA; Bleackley RC
    J Cell Sci; 2006 Mar; 119(Pt 5):858-65. PubMed ID: 16495481
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Importance of the P4' residue in human granzyme B inhibitors and substrates revealed by scanning mutagenesis of the proteinase inhibitor 9 reactive center loop.
    Sun J; Whisstock JC; Harriott P; Walker B; Novak A; Thompson PE; Smith AI; Bird PI
    J Biol Chem; 2001 May; 276(18):15177-84. PubMed ID: 11278311
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Identification of the BCL2/adenovirus E1B-19K protein-interacting protein 2 (BNIP-2) as a granzyme B target during human natural killer cell-mediated killing.
    Scott GB; Bowles PA; Wilson EB; Meade JL; Low BC; Davison A; Blair GE; Cook GP
    Biochem J; 2010 Nov; 431(3):423-31. PubMed ID: 20704564
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The crystal structure of PR3, a neutrophil serine proteinase antigen of Wegener's granulomatosis antibodies.
    Fujinaga M; Chernaia MM; Halenbeck R; Koths K; James MN
    J Mol Biol; 1996 Aug; 261(2):267-78. PubMed ID: 8757293
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Characterization of three serine esterases isolated from human IL-2 activated killer cells.
    Hameed A; Lowrey DM; Lichtenheld M; Podack ER
    J Immunol; 1988 Nov; 141(9):3142-7. PubMed ID: 3262682
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Cleavage of caspase family members by granzyme B: a comparative study in vitro.
    Van de Craen M; Van den Brande I; Declercq W; Irmler M; Beyaert R; Tschopp J; Fiers W; Vandenabeele P
    Eur J Immunol; 1997 May; 27(5):1296-9. PubMed ID: 9174624
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.