BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

139 related articles for article (PubMed ID: 11212114)

  • 1. Synthesis and biological activity of novel potent endothelin-converting enzyme-1 inhibitors.
    Firooznia F; Gude C; Chan K; Fink CA; Qiao Y; Satoh Y; Marcopoulos N; Savage P; Beil ME; Bruseo CW; Trapani AJ; Jeng AY
    Bioorg Med Chem Lett; 2001 Feb; 11(3):375-8. PubMed ID: 11212114
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Synthesis and biological activity of potent heterocyclic thiol-based inhibitors of endothelin-converting enzyme-1.
    Firooznia F; Gude C; Chan K; Tan J; Fink CA; Savage P; Beil ME; Bruseo CW; Trapani AJ; Jeng AY
    Bioorg Med Chem Lett; 2002 Nov; 12(21):3059-62. PubMed ID: 12372501
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Design and synthesis of potent thiol-based inhibitors of endothelin converting enzyme-1.
    Fink CA; Moskal M; Firooznia F; Hoyer D; Symonsbergen D; Wei D; Qiao Y; Savage P; Beil ME; Trapani AJ; Jeng AY
    Bioorg Med Chem Lett; 2000 Sep; 10(17):2037-9. PubMed ID: 10987444
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Potent and selective non-peptidic inhibitors of endothelin-converting enzyme-1 with sustained duration of action.
    De Lombaert S; Blanchard L; Stamford LB; Tan J; Wallace EM; Satoh Y; Fitt J; Hoyer D; Simonsbergen D; Moliterni J; Marcopoulos N; Savage P; Chou M; Trapani AJ; Jeng AY
    J Med Chem; 2000 Feb; 43(3):488-504. PubMed ID: 10669576
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Novel, selective indole-based ECE inhibitors: lead optimization via solid-phase and classical synthesis.
    Brands M; Ergüden JK; Hashimoto K; Heimbach D; Schröder C; Siegel S; Stasch JP; Weigand S
    Bioorg Med Chem Lett; 2005 Oct; 15(19):4201-5. PubMed ID: 16085415
    [TBL] [Abstract][Full Text] [Related]  

  • 6. CGS 34043: a non-peptidic, potent and long-acting dual inhibitor of endothelin converting enzyme-1 and neutral endopeptidase 24.11.
    Trapani AJ; De Lombaert S; Beil ME; Bruseo CW; Savage P; Chou M; Jeng AY
    Life Sci; 2000; 67(9):1025-33. PubMed ID: 10954036
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Design and synthesis of potent, selective inhibitors of endothelin-converting enzyme.
    Wallace EM; Moliterni JA; Moskal MA; Neubert AD; Marcopulos N; Stamford LB; Trapani AJ; Savage P; Chou M; Jeng AY
    J Med Chem; 1998 Apr; 41(9):1513-23. PubMed ID: 9554884
    [TBL] [Abstract][Full Text] [Related]  

  • 8. CGS 35601 and its orally active prodrug CGS 37808 as triple inhibitors of endothelin-converting enzyme-1, neutral endopeptidase 24.11, and angiotensin-converting enzyme.
    Trapani AJ; Beil ME; Bruseo CW; Savage P; Firooznia F; Jeng AY
    J Cardiovasc Pharmacol; 2004 Nov; 44 Suppl 1():S211-5. PubMed ID: 15838282
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Effects of the ECE/NEP inhibitor CGS 34225 on the big ET-1-induced pressor response and plasma atrial natriuretic peptide concentration in conscious rats.
    Trapani AJ; Beil ME; Bruseo CW; Fink CA; Hoyer D; Savage P; Jeng AY
    Clin Sci (Lond); 2002 Aug; 103 Suppl 48():102S-106S. PubMed ID: 12193065
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Design and synthesis of a potent and selective endothelin-converting enzyme inhibitor, CGS 35066.
    Jeng AY; De Lombaert S; Beil ME; Bruseo CW; Savage P; Chou M; Trapani AJ
    J Cardiovasc Pharmacol; 2000 Nov; 36(5 Suppl 1):S36-9. PubMed ID: 11078330
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Benzofused macrocyclic lactams as triple inhibitors of endothelin-converting enzyme, neutral endopeptidase 24.11, and angiotensin-converting enzyme.
    Ksander GM; Savage P; Trapani AJ; Balwierczak JL; Jeng AY
    J Cardiovasc Pharmacol; 1998; 31 Suppl 1():S71-3. PubMed ID: 9595404
    [TBL] [Abstract][Full Text] [Related]  

  • 12. CGS 34226, a thiol-based dual inhibitor of endothelin converting enzyme-1 and neutral endopeptidase 24.11.
    Jeng AY; Savage P; Beil ME; Bruseo CW; Hoyer D; Fink CA; Trapani AJ
    Clin Sci (Lond); 2002 Aug; 103 Suppl 48():98S-101S. PubMed ID: 12193064
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Phosphinic tripeptides as dual angiotensin-converting enzyme C-domain and endothelin-converting enzyme-1 inhibitors.
    Jullien N; Makritis A; Georgiadis D; Beau F; Yiotakis A; Dive V
    J Med Chem; 2010 Jan; 53(1):208-20. PubMed ID: 19899765
    [TBL] [Abstract][Full Text] [Related]  

  • 14. In-silico characterization of ECE-1 inhibitors.
    Ajay Babu P; Colluru VT; Anaparthy N
    Comput Biol Med; 2012 Apr; 42(4):446-57. PubMed ID: 22245098
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Characterization of CGS 31447, a potent and nonpeptidic endothelin-converting enzyme inhibitor.
    Shetty SS; Savage P; DelGrande D; De Lombaert S; Jeng AY
    J Cardiovasc Pharmacol; 1998; 31 Suppl 1():S68-70. PubMed ID: 9595403
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Selective indole-based ECE inhibitors: synthesis and pharmacological evaluation.
    Brands M; Ergüden JK; Hashimoto K; Heimbach D; Krahn T; Schröder C; Siegel S; Stasch JP; Tsujishita H; Weigand S; Yoshida NH
    ChemMedChem; 2006 Jan; 1(1):96-105. PubMed ID: 16892341
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Design and synthesis of diversely substituted azacyclic inhibitors of endothelin converting enzyme.
    Hanessian S; Gauchet C; Charron G; Marin J; Nakache P
    J Org Chem; 2006 Mar; 71(7):2760-78. PubMed ID: 16555831
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Targeting ACE and ECE with dual acting inhibitors.
    Hanessian S; Guesné S; Riber L; Marin J; Benoist A; Mennecier P; Rupin A; Verbeuren TJ; De Nanteuil G
    Bioorg Med Chem Lett; 2008 Feb; 18(3):1058-62. PubMed ID: 18160283
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Synthesis of novel substituted pyridines as inhibitors of endothelin converting enzyme-1 (ECE-1).
    Massa MA; Patt WC; Ahn K; Sisneros AM; Herman SB; Doherty A
    Bioorg Med Chem Lett; 1998 Aug; 8(16):2117-22. PubMed ID: 9873497
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Inhibition of big ET-1-induced pressor response by an orally active dual inhibitor of endothelin-converting enzyme and neutral endopeptidase 24.11.
    Trapani AJ; De Lombaert S; Kuzmich S; Jeng AY
    J Cardiovasc Pharmacol; 1995; 26 Suppl 3():S69-71. PubMed ID: 8587471
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.