462 related articles for article (PubMed ID: 11230124)
1. Recruitment, activation and retention of caspases-9 and -3 by Apaf-1 apoptosome and associated XIAP complexes.
Bratton SB; Walker G; Srinivasula SM; Sun XM; Butterworth M; Alnemri ES; Cohen GM
EMBO J; 2001 Mar; 20(5):998-1009. PubMed ID: 11230124
[TBL] [Abstract][Full Text] [Related]
2. Caspase-3 cleaves Apaf-1 into an approximately 30 kDa fragment that associates with an inappropriately oligomerized and biologically inactive approximately 1.4 MDa apoptosome complex.
Bratton SB; Walker G; Roberts DL; Cain K; Cohen GM
Cell Death Differ; 2001 Apr; 8(4):425-33. PubMed ID: 11550094
[TBL] [Abstract][Full Text] [Related]
3. Pro-apoptotic proteins released from the mitochondria regulate the protein composition and caspase-processing activity of the native Apaf-1/caspase-9 apoptosome complex.
Twiddy D; Brown DG; Adrain C; Jukes R; Martin SJ; Cohen GM; MacFarlane M; Cain K
J Biol Chem; 2004 May; 279(19):19665-82. PubMed ID: 14993223
[TBL] [Abstract][Full Text] [Related]
4. Caspase-7 is directly activated by the approximately 700-kDa apoptosome complex and is released as a stable XIAP-caspase-7 approximately 200-kDa complex.
Twiddy D; Cohen GM; Macfarlane M; Cain K
J Biol Chem; 2006 Feb; 281(7):3876-88. PubMed ID: 16352606
[TBL] [Abstract][Full Text] [Related]
5. Transforming growth factor-beta(1) induces apoptosis in rat FaO hepatoma cells via cytochrome c release and oligomerization of Apaf-1 to form a approximately 700-kd apoptosome caspase-processing complex.
Freathy C; Brown DG; Roberts RA; Cain K
Hepatology; 2000 Oct; 32(4 Pt 1):750-60. PubMed ID: 11003619
[TBL] [Abstract][Full Text] [Related]
6. Negative regulation of the Apaf-1 apoptosome by Hsp70.
Saleh A; Srinivasula SM; Balkir L; Robbins PD; Alnemri ES
Nat Cell Biol; 2000 Aug; 2(8):476-83. PubMed ID: 10934467
[TBL] [Abstract][Full Text] [Related]
7. Heat-shock protein 70 inhibits apoptosis by preventing recruitment of procaspase-9 to the Apaf-1 apoptosome.
Beere HM; Wolf BB; Cain K; Mosser DD; Mahboubi A; Kuwana T; Tailor P; Morimoto RI; Cohen GM; Green DR
Nat Cell Biol; 2000 Aug; 2(8):469-75. PubMed ID: 10934466
[TBL] [Abstract][Full Text] [Related]
8. XIAP inhibition of caspase-3 preserves its association with the Apaf-1 apoptosome and prevents CD95- and Bax-induced apoptosis.
Bratton SB; Lewis J; Butterworth M; Duckett CS; Cohen GM
Cell Death Differ; 2002 Sep; 9(9):881-92. PubMed ID: 12181739
[TBL] [Abstract][Full Text] [Related]
9. Chemical-induced apoptosis: formation of the Apaf-1 apoptosome.
Cain K
Drug Metab Rev; 2003 Nov; 35(4):337-63. PubMed ID: 14705865
[TBL] [Abstract][Full Text] [Related]
10. Regulation of the Apaf-1/caspase-9 apoptosome by caspase-3 and XIAP.
Zou H; Yang R; Hao J; Wang J; Sun C; Fesik SW; Wu JC; Tomaselli KJ; Armstrong RC
J Biol Chem; 2003 Mar; 278(10):8091-8. PubMed ID: 12506111
[TBL] [Abstract][Full Text] [Related]
11. Alpha-fetoprotein antagonizes X-linked inhibitor of apoptosis protein anticaspase activity and disrupts XIAP-caspase interaction.
Dudich E; Semenkova L; Dudich I; Denesyuk A; Tatulov E; Korpela T
FEBS J; 2006 Aug; 273(16):3837-49. PubMed ID: 16869888
[TBL] [Abstract][Full Text] [Related]
12. Differential sensitivity to apoptosome apparatus activation in non-small cell lung carcinoma and the lung.
Moravcikova E; Krepela E; Prochazka J; Benkova K; Pauk N
Int J Oncol; 2014 May; 44(5):1443-54. PubMed ID: 24626292
[TBL] [Abstract][Full Text] [Related]
13. Apaf-1 oligomerizes into biologically active approximately 700-kDa and inactive approximately 1.4-MDa apoptosome complexes.
Cain K; Bratton SB; Langlais C; Walker G; Brown DG; Sun XM; Cohen GM
J Biol Chem; 2000 Mar; 275(9):6067-70. PubMed ID: 10692394
[TBL] [Abstract][Full Text] [Related]
14. A nucleotide binding site in caspase-9 regulates apoptosome activation.
Chereau D; Zou H; Spada AP; Wu JC
Biochemistry; 2005 Apr; 44(13):4971-6. PubMed ID: 15794635
[TBL] [Abstract][Full Text] [Related]
15. Physiological concentrations of K+ inhibit cytochrome c-dependent formation of the apoptosome.
Cain K; Langlais C; Sun XM; Brown DG; Cohen GM
J Biol Chem; 2001 Nov; 276(45):41985-90. PubMed ID: 11553634
[TBL] [Abstract][Full Text] [Related]
16. A novel Apaf-1-independent putative caspase-2 activation complex.
Read SH; Baliga BC; Ekert PG; Vaux DL; Kumar S
J Cell Biol; 2002 Dec; 159(5):739-45. PubMed ID: 12460989
[TBL] [Abstract][Full Text] [Related]
17. Formation of apoptosome is initiated by cytochrome c-induced dATP hydrolysis and subsequent nucleotide exchange on Apaf-1.
Kim HE; Du F; Fang M; Wang X
Proc Natl Acad Sci U S A; 2005 Dec; 102(49):17545-50. PubMed ID: 16251271
[TBL] [Abstract][Full Text] [Related]
18. Role of cytochrome c and dATP/ATP hydrolysis in Apaf-1-mediated caspase-9 activation and apoptosis.
Hu Y; Benedict MA; Ding L; Núñez G
EMBO J; 1999 Jul; 18(13):3586-95. PubMed ID: 10393175
[TBL] [Abstract][Full Text] [Related]
19. Intracellular nucleotides act as critical prosurvival factors by binding to cytochrome C and inhibiting apoptosome.
Chandra D; Bratton SB; Person MD; Tian Y; Martin AG; Ayres M; Fearnhead HO; Gandhi V; Tang DG
Cell; 2006 Jun; 125(7):1333-46. PubMed ID: 16814719
[TBL] [Abstract][Full Text] [Related]
20. Apo cytochrome c inhibits caspases by preventing apoptosome formation.
Martin AG; Nguyen J; Wells JA; Fearnhead HO
Biochem Biophys Res Commun; 2004 Jul; 319(3):944-50. PubMed ID: 15184073
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]