283 related articles for article (PubMed ID: 11230698)
1. Role of the sphingosine-1-phosphate receptor EDG-1 in PDGF-induced cell motility.
Hobson JP; Rosenfeldt HM; Barak LS; Olivera A; Poulton S; Caron MG; Milstien S; Spiegel S
Science; 2001 Mar; 291(5509):1800-3. PubMed ID: 11230698
[TBL] [Abstract][Full Text] [Related]
2. EDG-1 links the PDGF receptor to Src and focal adhesion kinase activation leading to lamellipodia formation and cell migration.
Rosenfeldt HM; Hobson JP; Maceyka M; Olivera A; Nava VE; Milstien S; Spiegel S
FASEB J; 2001 Dec; 15(14):2649-59. PubMed ID: 11726541
[TBL] [Abstract][Full Text] [Related]
3. The sphingosine-1-phosphate receptor EDG-1 is essential for platelet-derived growth factor-induced cell motility.
Rosenfeldt HM; Hobson JP; Milstien S; Spiegel S
Biochem Soc Trans; 2001 Nov; 29(Pt 6):836-9. PubMed ID: 11709084
[TBL] [Abstract][Full Text] [Related]
4. Sphingosine-1-phosphate, a platelet-derived lysophospholipid mediator, negatively regulates cellular Rac activity and cell migration in vascular smooth muscle cells.
Ryu Y; Takuwa N; Sugimoto N; Sakurada S; Usui S; Okamoto H; Matsui O; Takuwa Y
Circ Res; 2002 Feb; 90(3):325-32. PubMed ID: 11861422
[TBL] [Abstract][Full Text] [Related]
5. Inhibitory regulation of Rac activation, membrane ruffling, and cell migration by the G protein-coupled sphingosine-1-phosphate receptor EDG5 but not EDG1 or EDG3.
Okamoto H; Takuwa N; Yokomizo T; Sugimoto N; Sakurada S; Shigematsu H; Takuwa Y
Mol Cell Biol; 2000 Dec; 20(24):9247-61. PubMed ID: 11094076
[TBL] [Abstract][Full Text] [Related]
6. c-Src is involved in regulating signal transmission from PDGFbeta receptor-GPCR(s) complexes in mammalian cells.
Waters CM; Connell MC; Pyne S; Pyne NJ
Cell Signal; 2005 Feb; 17(2):263-77. PubMed ID: 15494217
[TBL] [Abstract][Full Text] [Related]
7. Pericyte-specific expression of Rgs5: implications for PDGF and EDG receptor signaling during vascular maturation.
Cho H; Kozasa T; Bondjers C; Betsholtz C; Kehrl JH
FASEB J; 2003 Mar; 17(3):440-2. PubMed ID: 12514120
[TBL] [Abstract][Full Text] [Related]
8. G12/13 and Gq mediate S1P2-induced inhibition of Rac and migration in vascular smooth muscle in a manner dependent on Rho but not Rho kinase.
Takashima S; Sugimoto N; Takuwa N; Okamoto Y; Yoshioka K; Takamura M; Takata S; Kaneko S; Takuwa Y
Cardiovasc Res; 2008 Sep; 79(4):689-97. PubMed ID: 18480127
[TBL] [Abstract][Full Text] [Related]
9. Sphingosine kinase expression increases intracellular sphingosine-1-phosphate and promotes cell growth and survival.
Olivera A; Kohama T; Edsall L; Nava V; Cuvillier O; Poulton S; Spiegel S
J Cell Biol; 1999 Nov; 147(3):545-58. PubMed ID: 10545499
[TBL] [Abstract][Full Text] [Related]
10. Role of the sphingosine 1-phosphate receptor EDG-1 in vascular smooth muscle cell proliferation and migration.
Kluk MJ; Hla T
Circ Res; 2001 Sep; 89(6):496-502. PubMed ID: 11557736
[TBL] [Abstract][Full Text] [Related]
11. Edg-1, the G protein-coupled receptor for sphingosine-1-phosphate, is essential for vascular maturation.
Liu Y; Wada R; Yamashita T; Mi Y; Deng CX; Hobson JP; Rosenfeldt HM; Nava VE; Chae SS; Lee MJ; Liu CH; Hla T; Spiegel S; Proia RL
J Clin Invest; 2000 Oct; 106(8):951-61. PubMed ID: 11032855
[TBL] [Abstract][Full Text] [Related]
12. Sphingosine-1-phosphate inhibits motility of human breast cancer cells independently of cell surface receptors.
Wang F; Van Brocklyn JR; Edsall L; Nava VE; Spiegel S
Cancer Res; 1999 Dec; 59(24):6185-91. PubMed ID: 10626811
[TBL] [Abstract][Full Text] [Related]
13. Sphingosine 1-phosphate stimulates cell migration through a G(i)-coupled cell surface receptor. Potential involvement in angiogenesis.
Wang F; Van Brocklyn JR; Hobson JP; Movafagh S; Zukowska-Grojec Z; Milstien S; Spiegel S
J Biol Chem; 1999 Dec; 274(50):35343-50. PubMed ID: 10585401
[TBL] [Abstract][Full Text] [Related]
14. Akt-mediated phosphorylation of the G protein-coupled receptor EDG-1 is required for endothelial cell chemotaxis.
Lee MJ; Thangada S; Paik JH; Sapkota GP; Ancellin N; Chae SS; Wu M; Morales-Ruiz M; Sessa WC; Alessi DR; Hla T
Mol Cell; 2001 Sep; 8(3):693-704. PubMed ID: 11583630
[TBL] [Abstract][Full Text] [Related]
15. Divergence in signal transduction pathways of platelet-derived growth factor (PDGF) and epidermal growth factor (EGF) receptors. Involvement of sphingosine 1-phosphate in PDGF but not EGF signaling.
Rani CS; Wang F; Fuior E; Berger A; Wu J; Sturgill TW; Beitner-Johnson D; LeRoith D; Varticovski L; Spiegel S
J Biol Chem; 1997 Apr; 272(16):10777-83. PubMed ID: 9099730
[TBL] [Abstract][Full Text] [Related]
16. Sphingosine 1-phosphate stimulates proliferation and migration of human endothelial cells possibly through the lipid receptors, Edg-1 and Edg-3.
Kimura T; Watanabe T; Sato K; Kon J; Tomura H; Tamama K; Kuwabara A; Kanda T; Kobayashi I; Ohta H; Ui M; Okajima F
Biochem J; 2000 May; 348 Pt 1(Pt 1):71-6. PubMed ID: 10794715
[TBL] [Abstract][Full Text] [Related]
17. Extracellular mechanism through the Edg family of receptors might be responsible for sphingosine-1-phosphate-induced regulation of DNA synthesis and migration of rat aortic smooth-muscle cells.
Tamama K; Kon J; Sato K; Tomura H; Kuwabara A; Kimura T; Kanda T; Ohta H; Ui M; Kobayashi I; Okajima F
Biochem J; 2001 Jan; 353(Pt 1):139-146. PubMed ID: 11115407
[TBL] [Abstract][Full Text] [Related]
18. Platelet-derived growth factor (PDGF)-induced chemotaxis does not require the G protein-coupled receptor S1P1 in murine embryonic fibroblasts and vascular smooth muscle cells.
Kluk MJ; Colmont C; Wu MT; Hla T
FEBS Lett; 2003 Jan; 533(1-3):25-8. PubMed ID: 12505153
[TBL] [Abstract][Full Text] [Related]
19. Sphingosine-1-phosphate as a ligand for the G protein-coupled receptor EDG-1.
Lee MJ; Van Brocklyn JR; Thangada S; Liu CH; Hand AR; Menzeleev R; Spiegel S; Hla T
Science; 1998 Mar; 279(5356):1552-5. PubMed ID: 9488656
[TBL] [Abstract][Full Text] [Related]
20. Sphingosine 1-phosphate stimulation of the p42/p44 mitogen-activated protein kinase pathway in airway smooth muscle. Role of endothelial differentiation gene 1, c-Src tyrosine kinase and phosphoinositide 3-kinase.
Rakhit S; Conway AM; Tate R; Bower T; Pyne NJ; Pyne S
Biochem J; 1999 Mar; 338 ( Pt 3)(Pt 3):643-9. PubMed ID: 10051434
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
